Results 31 to 40 of about 431,159 (301)

Can we prevent antimicrobial resistance by using antimicrobials better? [PDF]

open access: yes, 2013
Since their development over 60 years ago, antimicrobials have become an integral part of healthcare practice worldwide. Recently, this has been put in jeopardy by the emergence of widespread antimicrobial resistance, which is one of the major problems ...
Brown   +27 more
core   +2 more sources

Ampicillin in Treatment of Certain Gram-negative Bacterial Infections [PDF]

open access: yesBMJ, 1963
Ampicillin, the first semisynthetic penicillin active against Gram-negative pathogens, is bactericidal in vitro to Escherichia coli, certain Proteus spp., some Klebsiella strains, salmonellae, and shigellae. The susceptible range of Gram-positive organisms is the same for ampicillin as for benzylpenicillin, although ampicillin is much less potent ...
W P, KENNEDY, A T, WALLACE, J M, MURDOCH
openaire   +2 more sources

Resistance trends in gram-negative bacteria: surveillance results from two Mexican hospitals, 2005–2010

open access: yesBMC Research Notes, 2012
Background Hospital-acquired infections caused by multiresistant gram-negative bacteria are difficult to treat and cause high rates of morbidity and mortality.
Morfin-Otero Rayo   +7 more
doaj   +1 more source

Epidemiology of patients with central nervous system infections, mainly neurosurgical patients: a retrospective study from 2012 to 2019 in a teaching hospital in China

open access: yesBMC Infectious Diseases, 2021
Background Central nervous system (CNS) infections are relatively rare but are associated with high mortality worldwide. Empirical antimicrobial therapy is crucial for the survival of patients with CNS infections, and should be based on the knowledge of ...
Zheng Zhang   +6 more
doaj   +1 more source

Difference of Procalcitonin Levels in Gram-Positive and Gram-Negative Bacterial Sepsis Patients of Indonesia Army Central Hospital Gatot Soebroto in 2016

open access: yesJuxta: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga, 2022
Introduction: Procalcitonin is known as a marker of infection and indicator for severity of infections. In sepsis, elevated procalcitonin levels in blood have a significant value that can be used as a sepsis biomarker.
Nindy Handayani   +2 more
doaj   +1 more source

Pleural effusion adenosine deaminase: a candidate biomarker to discriminate between Gram-negative and Gram-positive bacterial infections of the pleural space

open access: yesClinics, 2016
OBJECTIVES: Delay in the treatment of pleural infection may contribute to its high mortality. In this retrospective study, we aimed to evaluate the diagnostic accuracy of pleural adenosine deaminase in discrimination between Gram-negative and Gram ...
Ruolin Li   +3 more
doaj   +1 more source

TFPI-2 Protects Against Gram-Negative Bacterial Infection [PDF]

open access: yesFrontiers in Immunology, 2018
Tissue factor pathway inhibitor-2 (TFPI-2) has previously been characterized as an endogenous anticoagulant. TFPI-2 is expressed in the vast majority of cells, mainly secreted into the extracellular matrix. Recently we reported that EDC34, a C-terminal peptide derived from TFPI-2, exerts a broad antimicrobial activity. In the present study, we describe
Mohamad N. Ali   +12 more
openaire   +6 more sources

Role of lactobacilli and lactoferrin in the mucosal cervicovaginal defense [PDF]

open access: yes, 2018
Human lactoferrin is an iron-binding glycoprotein present at high concentrations in breast milk and colostrum. It is produced by many exocrine glands and widely distributed in a variety of body fluids.
Aagaard   +156 more
core   +2 more sources

Construction of a Bacterial Lipidomics Analytical Platform: Pilot Validation with Bovine Paratuberculosis Serum

open access: yesMetabolites, 2023
Lipidomics analyses of bacteria offer the potential to detect and monitor infections in a host since many bacterial lipids are not present in mammals. To evaluate this omics approach, we first built a database of bacterial lipids for representative Gram ...
Paul L. Wood, Erdal Erol
doaj   +1 more source

Selective detection of bacterial layers with terahertz plasmonic antennas [PDF]

open access: yes, 2012
Current detection and identification of micro-organisms is based on either rather unspecific rapid microscopy or on more accurate complex, time-consuming procedures.
Abbas   +16 more
core   +2 more sources

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