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Bcr4 Is a Chaperone for the Inner Rod Protein in the Bordetella Type III Secretion System

open access: yesMicrobiology Spectrum, 2022
Bordetella bronchiseptica injects virulence proteins called effectors into host cells via a type III secretion system (T3SS) conserved among many Gram-negative bacteria.
Masataka Goto   +4 more
doaj   +1 more source

Analysis of Microbial Communities: An Emerging Tool in Forensic Sciences

open access: yesDiagnostics, 2021
The objective of forensic sciences is to find clues in a crime scene in order to reconstruct the scenario. Classical samples include DNA or fingerprints, but both have inherent limitations and can be uninformative.
Audrey Gouello   +3 more
doaj   +1 more source

WGS based analysis of acquired antimicrobial resistance in human and non-human Acinetobacter baumannii isolates from a German perspective

open access: yesBMC Microbiology, 2021
Background Acinetobacter baumannii ability to develop and acquire resistance makes it one of the most critical nosocomial pathogens globally. Whole-genome sequencing (WGS) was applied to identify the acquired or mutational variants of antimicrobial ...
Gamal Wareth   +4 more
doaj   +1 more source

Evidence for Multi-Organ Infection During Experimental Meningococcal Sepsis due to ST-11 Isolates in Human Transferrin-Transgenic Mice

open access: yesMicroorganisms, 2020
The description of invasive meningococcal disease that is provoked by Neisseria meningitidis (Nm) is frequently restricted to meningitis. However, a wide panel of clinical presentations can be encountered including severe forms with intense inflammatory ...
Michael Levy   +2 more
doaj   +1 more source

Methicillin-resistant Staphylococcus pseudintermedius synthesizes deoxyadenosine to cause persistent infection

open access: yesVirulence, 2021
Methicillin-resistant Staphylococcus pseudintermedius (MRSP) is an emerging zoonotic pathogen of canine origin that causes an array of fatal diseases, including bacteremia and endocarditis.
Dorothea Bünsow   +6 more
doaj   +1 more source

Direct RNA Sequencing Unfolds the Complex Transcriptome of Vibrio parahaemolyticus

open access: yesmSystems, 2021
Conventional bacterial genome annotation provides information about coding sequences but ignores untranslated regions and operons. However, untranslated regions contain important regulatory elements as well as targets for many regulatory factors, such as
Mohamad Al kadi   +7 more
doaj   +1 more source

Inflammasome Activation Induced by Perfringolysin O of Clostridium perfringens and Its Involvement in the Progression of Gas Gangrene

open access: yesFrontiers in Microbiology, 2019
Clostridium perfringens (C. perfringens) is Gram-positive anaerobic, spore-forming rod-shaped bacterial pathogen that is widely distributed in nature. This bacterium is known as the causative agent of a foodborne illness and of gas gangrene.
Kiyonobu Yamamura   +8 more
doaj   +1 more source

Phages against Noncapsulated Klebsiella pneumoniae: Broader Host range, Slower Resistance

open access: yesMicrobiology Spectrum, 2023
Klebsiella pneumoniae (Kp), a human gut colonizer and opportunistic pathogen, is a major contributor to the global burden of antimicrobial resistance. Virulent bacteriophages represent promising agents for decolonization and therapy.
Marta Lourenço   +7 more
doaj   +1 more source

Functional diversity of staphylococcal surface proteins at the host-microbe interface

open access: yesFrontiers in Microbiology, 2023
Surface proteins of Gram-positive pathogens are key determinants of virulence that substantially shape host-microbe interactions. Specifically, these proteins mediate host invasion and pathogen transmission, drive the acquisition of heme-iron from ...
Nicoletta Schwermann   +3 more
doaj   +1 more source

Exploiting Real-Time Genomic Surveillance Data To Assess 4CMenB Meningococcal Vaccine Performance in Scotland, 2015 to 2022

open access: yesmBio, 2023
The United Kingdom implemented the first national infant immunization schedule for the meningococcal vaccine 4CMenB (Bexsero) in September 2015, targeting serogroup B invasive meningococcal disease (IMD).
C. M. C. Rodrigues   +5 more
doaj   +1 more source

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