Results 81 to 90 of about 430,389 (345)

Unravelling the Differential Host Immuno-Inflammatory Responses to Staphylococcus aureus and Escherichia coli Infections in Sepsis

Vaccines, 2022
Previous reports from our lab have documented dysregulated host inflammatory reactions in response to bacterial infections in sepsis. Both Gram-negative bacteria (GNB) and Gram-positive bacteria (GPB) play a significant role in the development and ...
Ena Gupta, Sanni Kumar, Vijay Kumar Srivastava, Juhi Saxena, Arif Jamal Siddiqui, Sudhir Mehta, Sanket Kaushik, Anupam Jyoti   +7 more
doaj   +1 more source

A Randomized, Open-Label, Non-inferiority Clinical Trial Assessing 7 Versus 14 Days of Antimicrobial Therapy for Severe Multidrug-Resistant Gram-Negative Bacterial Infections: The OPTIMISE Trial Protocol [PDF]

, 2023
Beatriz Arns, Jaqueline Driemeyer Correia Horvath, Gabriela Soares Rech, Guilhermo Prates Sesin, Crepin Aziz Jose Oluwafoumi Agani, B Rosa, Tiago Marcon dos Santos, Liliane Spencer Bittencourt Brochier, Alexandre Biasi Cavalcanti, Bruno Martins Tomazini, Adriano José Pereira, Viviane Cordeiro Veiga, Giovana Marssola Nascimento, André C. Kalil, Alexandre Prehn Zavascki   +14 more
openalex   +1 more source

Self‐Powered Permeable Electronic Dressing for Exudate Management, Electrostimulation and Drug Delivery in Chronic Wound Healing

Advanced Functional Materials, EarlyView.
This study develops a self‐powered permeable electronic dressing (SPED) that synergistically integrates exudate management, electrical stimulation, and on‐demand drug delivery. The dressing effectively absorbs exudate while demonstrating potent antibacterial activity and accelerated tissue regeneration in diabetic mouse models, thereby promoting ...
Jiaheng Liang, Jingjing Fu, Jin Chai, Hongyu Jiang, Fan Chen, Yufei Zhang, Weihao Zhao, Xian Song, Zhihao Zhou, Lingtao Fang, Qiyao Huang, Peng Li, Zijian Zheng   +12 more
wiley   +1 more source

Dynamic Profiling of Lipoteichoic Acid (LTA) and/or Lipopolysaccharide (LPS) Positive Extracellular Vesicles in Plasma as Diagnostic and Prognostic Biomarkers for Bacterial Infection

Advanced Science
Bacterial extracellular vesicles (EVs) are emerging as promising biomarkers for diagnosing bacterial infections. This study explores the diagnostic potential of plasma EVs carrying bacterial lipopolysaccharide (LPS) or lipoteichoic acid (LTA).
Qianqian Gao, Wenwu Zhou, Nadira Nurxat, Ke Xu, Yunyun Xu, Wei Li, Tianchi Chen, Cong Hu, Liang Dong, Qian Liu, Min Li   +10 more
doaj   +1 more source

Test the effectiveness of some medications and vitamin D3 used against COVID-19 on Gram-positive and Gram-negative bacteria isolated from people infected with the Coronavirus

مجلة علوم ذي قار
The COVID-19 pandemic has led to a search for effective pharmaceuticals and vitamins to combat the virus. These therapies have antiviral capabilities and can affect both gram-negative and gram-positive bacteria.
Amal F. AL-Gorani, Hanan Saadon, Ahmed. K. Ajeel, Noor abd alkhudhur salman, Aya Talib jawad, Hussein Adnan Obaid, Hasan Mohsen Koti   +6 more
doaj   +1 more source

Double-carbapenem therapy in the treatment of multidrug resistant Gram-negative bacterial infections: a systematic review and meta-analysis

BMC Infectious Diseases, 2020
Background To compare the efficacy and safety of double-carbapenem therapy (DCT) with other antibiotics for the treatment of multidrug resistant (MDR) Gram-negative bacterial infections. Methods Cochrane Library, PubMed, Embase and Web of Science as well
Yuan-yuan Li, Jin Wang, Rui Wang, Yun Cai   +3 more
doaj   +1 more source

Selective detection of bacterial layers with terahertz plasmonic antennas [PDF]

, 2012
Current detection and identification of micro-organisms is based on either rather unspecific rapid microscopy or on more accurate complex, time-consuming procedures.
Abbas, Berrier, Berrier, Debuisson, Demchick, Efrima, Giannini, Gómez Rivas, Hu, Ivnitski, Lazcka, Markelz, Mazhorova, Smye, Su, Taylor, Walther   +16 more
core   +2 more sources

Antibiotic-Resistant Gram-Negative Bacterial Infections in Patients With Cancer [PDF]

Clinical Infectious Diseases, 2014
Patients with cancer are at high risk for infections caused by antibiotic resistant gram-negative bacteria. In this review, we summarize trends among the major pathogens and clinical syndromes associated with antibiotic resistant gram-negative bacterial infection in patients with malignancy, with special attention to carbapenem and expanded-spectrum β ...
Federico, Perez, Javier, Adachi, Robert A, Bonomo   +2 more
openaire   +2 more sources

Membrane Vesicles from Lacticaseibacillus Casei BL23 Exhibit Antimicrobial Activity Against Escherichia coli and Immunostimulatory Effects on Human Peripheral Blood Mononuclear Cells

Advanced Healthcare Materials, EarlyView.
Membrane vesicles derived from the probiotic Lacticaseibacillus casei BL23 demonstrate antimicrobial properties against Escherichia coli and a potential biological effect in improving the overall survival of C. elegans infected with Pseudomonas aeruginosa. These vesicles stimulated immune responses in primary cells without causing toxicity. Our results
Cecilia L. D'Antoni, Leila Pourtalebi Jahromi, Lorenzo Sana, Ana Paula Domínguez Rubio, Maja Dorfner, Jennifer Munkert, Heike Danzer, Philipp Arnold, Mikhail Lebedev, Esther Zanin, Oscar E. Pérez, Gregor Fuhrmann   +11 more
wiley   +1 more source

Identification of protein biomarkers to differentiate between gram-negative and gram-positive infections in adults suspected of sepsis

BMC Infectious Diseases
Background Sepsis is mostly caused by bacterial infections and requires a prompt diagnosis. There is a need for improved diagnostics by differentiating between gram-negative and gram-positive bacterial infections.
Mahnaz Irani Shemirani, Anna-Karin Pernestig, Jens Björkman, Diana Tilevik, Astrid von Mentzer, Mikael Ejdebäck, Anders Ståhlberg   +6 more
doaj   +1 more source