Results 101 to 110 of about 431,159 (301)

Use of Quinolones for the Treatment of Osteomyelitis and Septic Arthritis [PDF]

, 2017
The low minimal inhibitory concentrations and minimal bactericidal concentrations of the quinolones for most pathogenic gram-negative and many gram-positive organisms, the ease of their administration, and their good oral absorption make them good ...
Waldvogel, Francis A.
core  

An update on environmental mastitis: challenging perceptions [PDF]

, 2017
Environmental mastitis is the most common and costly form of mastitis in modern dairy herds where contagious transmission of intramammary pathogens is controlled through implementation of standard mastitis prevention programmes.
Klaas, I.C., Zadoks, R.N.
core   +1 more source

Enhanced Infection Resistance and Regenerative Healing of Titanium Implants via Peptide‐Loaded Biodegradable Coatings

Advanced Materials Technologies, EarlyView.
This study presents a new biodegradable coating for titanium implants using a natural antimicrobial peptide, caerin 1.9. Applied via solvent casting, the coating offers sustained antibacterial protection and promotes healing. Tested on 3D‐printed porous titanium scaffolds, it effectively prevented infection—including against resistant bacteria—while ...
Hejie Li, Tianfang Wang, Nicolas Soro, Guoying Ni, Meg Allom, D. İpek Kurtböke, Xiaosong Liu, Damon Kent   +7 more
wiley   +1 more source

Phage Therapy in Treatment of Gram-negative Bacterial Infections: A Systematic Review

Journal of Mazandaran University of Medical Sciences, 2018
Background and purpose: Infections caused by multidrug-resistant gram-negative bacteria are rising. Phage therapy is an effective treatment in infections resistant to treatment and progress has been made with its use and development in recent years ...
Golnar Rahimzadeh, Majid Saeedi, Fereshteh Farshidi, Mohammad Sadegh Rezai   +3 more
doaj  

Controversies in the Use of Passive Immunotherapy for Bacterial Infections in the Critically Ill Patient [PDF]

, 2017
Several preparations of standard immunoglobulins for intravenous use have been tested as adjunctive therapy for bacterial infections in premature neonates and in critically ill adults after major surgery, trauma, and burn.
Baumgartner, J. D., Glauser, M. P.
core  

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
wiley   +1 more source

Prevalence of multidrug-resistant bacterial isolates in sputum samples with respiratory infections from Indonesian patients

Frontiers in Tropical Diseases
ObjectiveMulti-drug resistant (MDR) bacterial infections have become a pressing global health issue due to increasing antibiotic resistance in clinical settings.
Abdul Rahman Siregar, Deivan Pradana Putra, Anggun Diyan Nurhasanah, Ayu Rahmawati Sulistyaningtyas, Aditya Rahman Ernanto, Afifah Khairunnisa, Wahyu Aristyaning Putri, Bayissa Chala, Rizal Maarif Rukmana, Sugiyono Saputra, Prakash Gosh, Ahmed Abd El-Wahed, Arif Mulyanto, Sri Darmawati   +13 more
doaj   +1 more source

Bacterial pathogens and resistance causing community acquired paediatric bloodstream infections in low- and middle-income countries: a systematic review and meta-analysis [PDF]

, 2019
Background Despite a high mortality rate in childhood, there is limited evidence on the causes and outcomes of paediatric bloodstream infections from low- and middle-income countries (LMICs).
Basmaci, R, Dramowski, A, Droz, N, Ellis, S, Hsia, Y, Sharland, M   +5 more
core   +2 more sources

A Bifunctional T3SS‐Effector Simultaneously Cleaves Host MAP Kinase and Inhibits PPM1A Phosphatase

Advanced Science, EarlyView.
Pathogenic bacteria exploit the metalloprotease effector NleD to subvert host defenses. Structural, biochemical, and infection analyses reveal a bifunctional mechanism by which NleD binds and inhibits the host phosphatase PPM1A while preserving its proteolytic activity against MAPKs.
Yaakov Socol, Lihi Gur‐Arie, Netanel Tzarum, Tamara Wellins, Naama Katsowich, Miriam Ravins, Michal Bejerano‐Sagie, Klil Cohen, Oded Livnah, Joshua N. Adkins, Ernesto Nakayasu, Alexei Savchenko, Yeu Khai Choong, Nikhil Kumar Tulsian, Saturo Machida, Sigal Ben‐Yehuda, Yael Litvak, J. Sivaraman, Ilan Rosenshine   +18 more
wiley   +1 more source

Prevalence and Antimicrobial Susceptibility Patterns of Bacterial Pathogens in Urinary Tract Infections in University Hospital of Campania “Luigi Vanvitelli” between 2017 and 2018

Antibiotics, 2020
Urinary tract infections (UTIs) are the most common and expensive health problem globally. The treatment of UTIs is difficult owing to the onset of antibiotic-resistant bacterial strains.
Veronica Folliero, Pina Caputo, Maria Teresa Della Rocca, Annalisa Chianese, Marilena Galdiero, Maria R. Iovene, Cameron Hay, Gianluigi Franci, Massimiliano Galdiero   +8 more
doaj   +1 more source