Results 91 to 100 of about 3,027,557 (384)

Treatment of Infections Due to MDR Gram-Negative Bacteria

Frontiers in Medicine, 2019
The treatment of multidrug-resistant Gram-negative bacteria (MDR-GNB) infections in critically ill patients presents many challenges. Since an effective treatment should be administered as soon as possible, resistance to many antimicrobial classes almost
M. Bassetti, M. Peghin, A. Vena, D. Giacobbe   +3 more
semanticscholar   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Terrestrial gamma radiation dose measurement and health hazard along river Alaknanda and Ganges in India

Journal of Radiation Research and Applied Sciences, 2014
Direct measurement of absorbed dose rate in air due to exposure from outdoor terrestrial γ radiation and assessment of consequent public health hazard continues to be of environmental and public concern.
Prerna Sharma, Prabodha Kumar Meher, Kaushala Prasad Mishra   +2 more
doaj   +1 more source

Assessment of the pesticidal behaviour of diacyl hydrazine-based ready-to-use nanoformulations

Chemical and Biological Technologies in Agriculture, 2020
Background Application of nanotechnology for crop protection in the form of nanopesticide has attracted significant interest in modern agriculture for the management of devastating polyphagous pests. In the present work, highly stable, ready-to-use water-
Alka Pandey, Shivani Srivastava, Nisha Aggarwal, Chitra Srivastava, Alok Adholeya, Mandira Kochar   +5 more
doaj   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Significance of Streptococcus gallolyticus subsp. gallolyticus Association With Colorectal Cancer

Frontiers in Microbiology, 2018
Streptococcus gallolyticus subsp. gallolyticus Sgg (formerly known as S. bovis type I) is the main causative agent of septicemia and infective endocarditis (IE) in elderly and immunocompromised persons. It belongs to the few opportunistic bacteria, which
Ewa Pasquereau-Kotula, Mariana Martins, Laetitia Aymeric, Shaynoor Dramsi   +3 more
doaj   +1 more source

Differential Pd-nanocrystal facets demonstrate distinct antibacterial activity against Gram-positive and Gram-negative bacteria

Nature Communications, 2018
Noble metal-based nanomaterials have shown promise as potential enzyme mimetics, but the facet effect and underlying molecular mechanisms are largely unknown.
Ge Fang, Weifeng Li, Xiaomei Shen, J. M. Perez-Aguilar, Yu Chong, Xingfa Gao, Z. Chai, Chunying Chen, Cuicui Ge, R. Zhou   +9 more
semanticscholar   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source

Permeability barriers of Gram‐negative pathogens

Annals of the New York Academy of Sciences, 2020
Most clinical antibiotics do not have efficacy against Gram‐negative pathogens, mainly because these cells are protected by the permeability barrier comprising the two membranes with active efflux.
H. Zgurskaya, V. Rybenkov
semanticscholar   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source