Meclizine and Cephalosporin Combination as Promising Antibiotic Drugs: Formulation, Antimicrobial, and <i>In Silico</i> Studies. [PDF]
Al-Madhagi WM +5 more
europepmc +1 more source
Dissolvable microneedle (MN) device containing Bacillus paralicheniformis. The polymeric matrix encapsulates and protects the bacteria, preserving their viability while enabling in situ production and release of γ‐polyglutamic acid. The bacteria are delivered into the skin via 500 µm‐long microneedles, and remain detectable on the skin 24 h post ...
Caroline Hali Alperovitz +3 more
wiley +1 more source
Bacterial etiology and antimicrobial resistance patterns of pediatric UTIs in the West bank, Palestine: a cross-sectional study. [PDF]
Amleh T +6 more
europepmc +1 more source
Plug‐and‐Play Centrifuge‐Only Device for Rapid Sepsis Diagnosis
A fully automated, centrifuge‐only device can isolate and concentrate bacteria from blood for rapid sepsis diagnosis. The device enables >3×$>3\times$ bacterial enrichment and removes >$>$99.9% of blood cells. The device supports direct downstream analysis via subculturing, MALDI‐TOF, and microfluidic detection of bacteria.
Mohammad Osaid +5 more
wiley +1 more source
In Vitro and In Silico Analysis of Differential Antibacterial Activity of Pomegranate Polyphenols Against Gram-Positive and Gram-Negative Bacteria. [PDF]
Suručić R +7 more
europepmc +1 more source
A transparent dual‐network strain sensor integrates robust mechanical properties, room‐temperature self‐healing, and stable performance under sub‐zero conditions and prolonged storage. Its excellent biocompatibility and antimicrobial properties enable safe skin contact.
Wenqing Chen +8 more
wiley +1 more source
In Vitro synergy of Farnesyltransferase inhibitors in combination with colistin against ESKAPE bacteria. [PDF]
Klose M, Weber L, Bachmann HS.
europepmc +1 more source
Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner +8 more
wiley +1 more source
Effect of biofire blood culture identification 2 (BCID2) panel versus a matrix-assisted laser desorption/ionization-time of flight mass spectrometry (MALDI-TOF MS) rapid incubation protocol on time to optimal therapy in patients with positive blood cultures. [PDF]
Baum A +4 more
europepmc +1 more source
A bone substitute with gentamicin physically precipitated onto the surface of carbonate apatite exhibits prompt drug release, high bactericidal activity, and osteogenic capacity. Efficient antibacterial activity mitigates early postoperative neutrophil accumulation, the status of which may serve as a potential parameter for evaluating the antibacterial
Linghao Xiao +6 more
wiley +1 more source

