Results 31 to 40 of about 2,485,409 (195)

Tolerance and Persistence of Pseudomonas aeruginosa in Biofilms Exposed to Antibiotics: Molecular Mechanisms, Antibiotic Strategies and Therapeutic Perspectives

open access: yesFrontiers in Microbiology, 2020
Pseudomonas aeruginosa biofilm-related infections are difficult to treat with antibiotics. Along the different layers of the biofilm, the P. aeruginosa population is heterogeneous, exhibiting an extreme ability to adapt his metabolic activity to the ...
Anaïs Soares   +4 more
doaj   +1 more source

Destabilization of α-helical structure in solution improves bactericidal activity of antimicrobial peptides: Opposing effects on bacterial and viral targets [PDF]

open access: yes, 2016
We have previously examined the mechanism of antimicrobial peptides on the outer membrane of vaccinia virus. Here we show that the formulation of peptides LL37 and magainin-2B amide in polysorbate 20 (Tween-20™) results in greater reductions in virus ...
Beck, Konrad   +4 more
core   +2 more sources

Characterization of an Endophytic Strain Talaromyces assiutensis, CPEF04 With Evaluation of Production Medium for Extracellular Red Pigments Having Antimicrobial and Anticancer Properties

open access: yesFrontiers in Microbiology, 2021
Considering the worldwide demand for colorants of natural origin, the utilization of ascomycete fungi as a prolific pigment producer unfolds a novel way to obtain these pigments for various applications, including food, cosmetic, and medical use.
Rahul Chandra Mishra   +5 more
doaj   +1 more source

Planning for town centre revitalisation in a declining context : a thesis presented in partial fulfilment of the requirements for the degree of Master of Resource and Environmental Planning at Massey University, Palmerston North, New Zealand [PDF]

open access: yes, 2017
"This research explored how the Ruapehu District views its declining population and economy, how town centre revitalisation has attempted to address decline in Ohakune, and the outcomes of this revitalisation, with the aim of developing guidelines for ...
Gram, Lauren
core  

Structure Based docking studies towards exploring potential anti-androgen activity of selected phytochemicals against Prostate Cancer

open access: yesScientific Reports, 2017
Prostate cancer (PCa) is the second most common malignancy amongst men worldwide. Under PCa maintenance therapy drugs acting as antagonists/partial agonists of hormone receptors against the prostate tissue are used in clinical practices.
Anshika N. Singh   +2 more
doaj   +1 more source

Investigation of antimicrobial susceptibility and genetic diversity among Staphylococcus pseudintermedius isolated from dogs in Rio de Janeiro

open access: yesScientific Reports, 2023
Staphylococcus pseudintermedius is an opportunistic pathogen causing a variety of infections that are difficult to treat, especially because of the development of antimicrobial resistance. It has a clonal distribution around the world.
Izabel Mello Teixeira   +11 more
doaj   +1 more source

Dapagliflozin stimulates glucagon secretion at high glucose: experiments and mathematical simulations of human A-cells. [PDF]

open access: yes, 2016
Glucagon is one of the main regulators of blood glucose levels and dysfunctional stimulus secretion coupling in pancreatic A-cells is believed to be an important factor during development of diabetes.
Ahlstedt, I.   +3 more
core   +1 more source

SOFIA®RSV: prospective laboratory evaluation and implementation of a rapid diagnostic test in a pediatric emergency ward

open access: yesBMC Infectious Diseases, 2017
Background Respiratory syncytial virus (RSV) is responsible for severe respiratory infections and higher costs in medical care. The two aims of this work were to assess the performances of SOFIA®RSV tests in “real-life-laboratory” conditions (study 1 ...
Léa C. Tran   +5 more
doaj   +1 more source

Combination of quercetin and 2-methoxyestradiol inhibits epithelial–mesenchymal transition in PC-3 cell line via Wnt signaling pathway

open access: yesFuture Science OA, 2021
Aim: We have previously reported that quercetin (Qu) regulates epithelial–mesenchymal transition (EMT) by modulating Wnt signaling components. In this study, we investigated the synergistic effect of Qu and 2-methoxyestradiol (2-ME) and the role of Wnt ...
Neeti Sharma   +3 more
doaj   +1 more source

Generalized Gram–Hadamard inequality [PDF]

open access: yes, 2010
We generalize the classical Gram determinant inequality. Our generalization follows from the boundedness of the antisymmetric tensor product operator.
Constantinescu, Florin (Prof. Dr.)   +1 more
core  

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