Results 61 to 70 of about 3,027,557 (384)
Phage inducible islands in the gram-positive cocci [PDF]
, 2016 The SaPIs are a cohesive subfamily of extremely common phage-inducible chromosomal islands (PICIs) that reside quiescently at specific att sites in the staphylococcal chromosome and are induced by helper phages to excise and replicate.
A Bolotin +47 more
core +1 more source
Automatic Evaluation of Summaries Using N-gram Co-occurrence Statistics
North American Chapter of the Association for Computational Linguistics, 2003 Following the recent adoption by the machine translation community of automatic evaluation using the BLEU/NIST scoring process, we conduct an in-depth study of a similar idea for evaluating summaries.
Chin-Yew Lin, E. Hovy
semanticscholar +1 more source
Mobile Oxazolidinone Resistance Genes in Gram-Positive and Gram-Negative Bacteria
Clinical Microbiology Reviews, 2021 Seven mobile oxazolidinone resistance genes, including cfr, cfr(B), cfr(C), cfr(D), cfr(E), optrA, and poxtA, have been identified to date. The cfr genes code for 23S rRNA methylases, which confer a multiresistance phenotype that includes resistance to ...
S. Schwarz +9 more
semanticscholar +1 more source
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Resurrection of Nalidixic Acid: Evaluation of Water-Based Nanoformulations as Potential Nanomedicine
Nanoscale Research Letters, 2018 Resistance to quinolone antibiotics has been a serious problem ever since nalidixic acid was introduced into clinical medicine. Over time, resistance of pathogenic microbes to nalidixic acid led to the design of novel variants to revive its potential ...
Alka Pandey +3 more
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Dimension of gram spectrahedra of univariate polynomials [PDF]
, 2015 The Gram Spectrahedron of a polynomial parametrizes its sums-of-squares representations.
Tsukerman, Emmanuel
core
Outer Membrane Vesicles (OMVs) of Gram-negative Bacteria: A Perspective Update
Frontiers in Microbiology, 2017 Outer Membrane Vesicles (OMVs) of Gram-negative bacteria are spherical membrane-enclosed entities of endocytic origin. Reported in the consortia of different bacterial species, production of OMVs into extracellular milieu seems essential for their ...
A. Jan
semanticscholar +1 more source
Extracellular Vesicle Biogenesis and Functions in Gram-Positive Bacteria
Infection and Immunity, 2020 Extracellular vesicles (EVs) are membrane-derived lipid bilayers secreted by bacteria and eukaryotic cells. Bacterial membrane vesicles were discovered over 60 years ago and have been extensively studied in Gram-negative bacteria. During their production,
Paul Briaud, Ronan K. Carroll
semanticscholar +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source