Results 1 to 10 of about 493,599 (258)

Repurposing Birabresib to target Gram‑positive bacteria [PDF]

npj Antimicrobials and Resistance
The threat of antibiotic-resistant bacteria is rapidly escalating, creating an urgent need for new types of antimicrobials. Although most antibiotics act by disrupting essential cellular processes, such as cell division, replication, transcription, and ...
Hazera Khatun Koly, Roha Razzaq, Tahmina Hossain, Nicholas C. Butzin   +3 more
doaj   +2 more sources

Quorum-Sensing Inhibition by Gram-Positive Bacteria

Microorganisms, 2022
The modern paradigm assumes that interspecies communication of microorganisms occurs through precise regulatory mechanisms. In particular, antagonism between bacteria or bacteria and fungi can be achieved by direct destruction of the targeted cells ...
Evgeniya V. Prazdnova, Andrey V. Gorovtsov, Nikita G. Vasilchenko, Maxim P. Kulikov, Varvara N. Statsenko, Anna A. Bogdanova, Alexandr G. Refeld, Yaroslav A. Brislavskiy, Vladimir A. Chistyakov, Michael L. Chikindas   +9 more
doaj   +3 more sources

Environmental microbial communications in gram-positive and gram-negative bacteria [PDF]

Global Journal of Environmental Science and Management, 2023
Microorganisms are present in nature and shape an enormous a half of our micro- and macro-environment. Quorum sensing is the process of intercellular conversation that enables microbes to perceive their surroundings and change their behaviour, allowing ...
P. Srikanth, D. Sivakumar, J. Nouri
doaj   +1 more source

In vitro efficacy of fosfomycin against clinical strains [PDF]

Journal of Microbiology and Infectious Diseases, 2014
Objective: Fosfomycin is an alternative drug for treatment of uncomplicated urinary tract infections. This study aimed to investigate in vitro activity of fosfomycin against ethicillinresistant Staphylococcus aureus (MRSA), methicillinresistant ...
Adil Karadağ , Yeliz Tanrıverdi Çaycı , Kemal Bilgin , Murat Günaydın, Cafer Eroğlu   +4 more
doaj   +3 more sources

SYNTHESIS, CHARACTERIZATION AND STUDY THE EFFECT OF (3,5-DIMETHYL-1H-PYRAZOL-4- YL) MERCURY (II) CHLORIDE ON GROWTH INHIBITION OF SOME BACTERIA ,YEAST AND SOME FUNGI (IN VITRO). [PDF]

Basrah Journal of Veterinary Research, 2008
The reaction of 3,5-dimethyl-1H-pyrazole with mercury (II)acetate in absolute methanol gave (3,5-dimethyl-1H-pyrazol-4-yl) mercury(II) chloride (DMPMC), which characterized by microanalysis, 1H, and 13C-NMR and IR.
Eman.T.Ali
doaj   +1 more source

Extracellular vesicle production in Gram‐positive bacteria

Microbial Biotechnology, 2022
Summary This is a highlight on the article ‘Extracellular vesicle formation in Lactococcus lactis is stimulated by prophage‐encoded holin‐lysin system’ by Yue Liu, Eddy Smid and Tjakko Abee.
Scott N. Dean, Meghna Thakur, Joseph R. Spangler   +2 more
doaj   +1 more source

Characterization of a triad of genes in cyanophage S-2L sufficient to replace adenine by 2-aminoadenine in bacterial DNA

Nature Communications, 2021
The cyanophage S-2L incorporates 2-aminoadenine (Z) instead of adenine into its DNA, which still pairs with thymine forming a triple hydrogen bond.
Dariusz Czernecki, Frédéric Bonhomme, Pierre-Alexandre Kaminski, Marc Delarue   +3 more
doaj   +1 more source

Phage Adsorption to Gram-Positive Bacteria

Viruses, 2023
The phage life cycle is a multi-stage process initiated by the recognition and attachment of the virus to its bacterial host. This adsorption step depends on the specific interaction between bacterial structures acting as receptors and viral proteins ...
Audrey Leprince, Jacques Mahillon
doaj   +1 more source

Organism type of infection is associated with prognosis in sepsis: an analysis from the MIMIC-IV database

BMC Infectious Diseases, 2023
Background Sepsis has a high mortality rate, which is expensive to treat, and is a major drain on healthcare resources; it seriously impacts the quality of human life.
Qiuping Guo, Peng Qu, Wanfu Cui, Mingrong Liu, Huiling Zhu, Weixin Chen, Nan Sun, Shiyu Geng, Weihua Song, Xu Li, Anni Lou   +10 more
doaj   +1 more source

Five-year period evaluation of isolated agents and their resistance profiles in intensive care unit patients with malignancy

Journal of Infection in Developing Countries, 2020
Introduction: Patients treated in the intensive care unit (ICU) are usually patients who deteriorated health condition and could have longer hospital stay compared to other patients. Hospital infections are more common in ICU patients.
Duygu Mert, Selda Muslu, Alparslan Merdin, Arif Timuroğlu, Ece Dirim, Süheyla Ünver, Mustafa Ertek   +6 more
doaj   +1 more source