Results 41 to 50 of about 950,611 (302)

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

Whose Tchaikovsky? Consumerism, nationality, sex and the curious case of the disappearing composer in Tchaikovsky and The Music Lovers

open access: yesCogent Arts & Humanities, 2014
This article offers the first sustained analysis of two films about the life of the composer Pyotr Ilyich Tchaikovsky made in 1969 and 1970 respectively. One of these, Ken Russell’s The Music Lovers (1970), is well known in the West.
John Gardiner
doaj   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Emergent grammar

open access: yesAnnual Meeting of the Berkeley Linguistics Society, 1987
Proceedings of the Thirteenth Annual Meeting of the Berkeley Linguistics Society (1987), pp.
openaire   +2 more sources

Added Prognostic Value of EEG Reactivity in Comatose Patients Following Cardiac Arrest

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the added prognostic value of EEG reactivity for favorable outcome compared with background analysis during and after targeted temperature management (TTM). Methods Prospective observational cohort study of comatose post–cardiac arrest patients admitted to a single academic center between 2017 and 2022, all undergoing ...
Sarah Caroyer   +11 more
wiley   +1 more source

Reflections on the new International Baccalaureate Diploma Classical Languages Syllabus

open access: yesThe Journal of Classics Teaching, 2023
At the end of January 2022 the International Baccalaureate Organisation (IBO) published the new Diploma syllabus for Classical Languages (for first assessment in 2024).
Simon Trafford
doaj   +1 more source

TuLiPA : a syntax-semantics parsing environment for mildly context-sensitive formalisms [PDF]

open access: yes, 2008
In this paper we present a parsing architecture that allows processing of different mildly context-sensitive formalisms, in particular Tree-Adjoining Grammar (TAG), Multi-Component Tree-Adjoining Grammar with Tree Tuples (TT-MCTAG) and simple Range ...
Dellert, Johannes   +4 more
core   +5 more sources

A Qualitative Analysis of Patient Perspectives and Preferences in Lupus Management to Guide Lupus Guidelines Development

open access: yesArthritis Care &Research, EarlyView.
Objective A patient‐centered approach for chronic disease management, including systemic lupus erythematosus (SLE), aligns treatment with patients’ values and preferences, leading to improved outcomes. This paper summarizes how patient experiences, perspectives, and priorities informed the American College of Rheumatology (ACR) 2024 Lupus Nephritis (LN)
Shivani Garg   +20 more
wiley   +1 more source

Dydaktyki filozofii kłopoty z prawdą [The teaching of philosophy and its troubles with truth] [PDF]

open access: yesAnaliza i Egzystencja, 2014
I. We can talk about the crisis of the truth (in the meaning of the classical cor- respondence theory) in the contemporary philosophy (of the 20th century). II.
Zbigniew Zdunowski
doaj  

Parallel Distributed Grammar Engineering for Practical Applications [PDF]

open access: yes, 2011
Based on a detailed case study of parallel grammar development distributed across two sites, we review some of the requirements for regression testing in grammar engineering, summarize our approach to systematic competence and performance profiling, and ...
Bender, Emily M.   +4 more
core  

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