Results 41 to 50 of about 2,695,498 (243)
Constructing Features for Screening Neurodevelopmental Disorders Using Grammatical Evolution
Applied Sciences, 2023 Developmental domains refer to different areas of a child’s growth and maturation, including physical, language, cognitive, and social–emotional skills. Understanding these domains helps parents, caregivers, and professionals track a child’s progress and
Eugenia I. Toki +3 more
doaj +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Predicting the Damage of Urban Fires with Grammatical Evolution
Big Data and Cognitive ComputingFire, whether wild or urban, depends on the triad of oxygen, fuel, and heat. Urban fires, although smaller in scale, have devastating impacts, as evidenced by the 2018 wildfire in Mati, Attica (Greece), which claimed 104 lives.
Constantina Kopitsa +3 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Restrictions on biological adaptation in language evolution [PDF]
, 2009 Language acquisition and processing are governed by genetic constraints. A crucial unresolved question is how far these genetic constraints have co-evolved with language, perhaps resulting in a highly specialized, and species-specific language “module”;
Reali, F. +5 more
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
IEEE Access, 2020 We present a new approach based on grammatical evolution (GE) aimed at addressing the analog electronic circuit design problem. In the new approach, called multi-grammatical evolution (MGE), a chromosome is a variable-length codon string that is divided ...
Federico Castejon, Enrique J. Carmona
doaj +1 more source
GELAB – The Cutting Edge of Grammatical Evolution
IEEE Access, 2022 The advent of cloud-based super-computing platforms has given rise to a Data Science (DS) boom. Many types of technological problems that were once considered prohibitively expensive to tackle are now candidates for exploration.
Krishn Kumar Gupt +4 more
doaj +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source