Results 81 to 90 of about 3,048,704 (321)

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Classification of Earthquakes Using Grammatical Evolution

Algorithms
Earthquake predictability remains a central challenge in seismology. Are earthquakes inherently unpredictable phenomena, or can they be forecasted through advances in technology?
Constantina Kopitsa, Ioannis G. Tsoulos, Vasileios Charilogis, Chrysostomos Stylios   +3 more
doaj   +1 more source

Constituent grammatical evolution [PDF]

, 2012
Evolutionary algorithms are a competent nature-inspired approach for complex computational problem solving. One recent development is Grammatical Evolution, a grammar-based evolutionary algorithm which uses genotypes of variable length binary strings and
Georgiou, Loukas
core  

GEVA : grammatical evolution in Java

, 2008
We are delighted to announce the release of GEVA an open source software implementation of Grammatical Evolution (GE) in Java. Grammatical Evolution in Java (GEVA) was developed at UCD’s Natural Computing Research & Applications group (http://ncra.ucd.ie)
Gilligan, Conor, McDermott, James, Hemberg, Erik, O'Neill, Michael, Brabazon, Anthony, Bartley, Eliott   +5 more
core   +1 more source

The evolution of grammatical structures and ‘functional need’ explanations

, 2023
When speaking about the way language evolved in human prehistory, it is highly implausible to assume that humans developed language because they needed it in order to adapt better, and faster, to their environment.
Comrie, B. ; https://orcid.org/, Kuteva, T.   +1 more
core   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Enhancing grammatical evolution

, 2010
Grammatical Evolution (GE) is a method of utilising a general purpose evolutionary algorithm to evolve programs written in an arbitrary BNF grammar. This thesis extends GE as follows: GE as an extension of Genetic Programming (GP) A novel method of automatically extracting information from the grammar is introduced.
openaire   +2 more sources

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source