Results 211 to 220 of about 9,057 (292)

Spatial Distribution of Prostate Cancer Missed by MRI‐Targeted Biopsy, Effect of a Perilesional Template, and Restaging in a Radical Prostatectomy Cohort

The Prostate, EarlyView.
ABSTRACT Purpose Systematic biopsy (SB) remains recommended in addition to MRI‐targeted biopsy (TB) because TB alone may miss clinically significant prostate cancer (sPC). We evaluated the spatial distribution of sPC and clinically insignificant prostate cancer (iPC) detected by SB in relation to MRI lesions and assessed the effect of perilesional ...
Ruth Himmelsbach, Julia Franz, Cordula Jilg, Christian Gratzke, August Sigle   +4 more
wiley   +1 more source

An intelligent framework combining deep learning and fuzzy logic for accurate remote language translation. [PDF]

Sci Rep
Geng C.
europepmc   +1 more source

Universal and Lineage‐Specific Patterns in the Distribution of ECOD Domain Homology Groups Across Superkingdoms

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Proteins are built from modular domains that serve as fundamental units of structure and evolution. While individual domains have been extensively cataloged, their collective distribution across the lineages of life has remained poorly resolved.
Rui Guo, Jimin Pei, Jing Zhang, Qian Cong, Nick V. Grishin, R. Dustin Schaeffer   +5 more
wiley   +1 more source

Modeling a Shared Reality of Tractography through Varied Structural Imaging. [PDF]

Proc SPIE Int Soc Opt Eng
Schwartz TM, McMaster EM, Rudravaram G, Cho C, Krishnan A, Kim ME, Samir J, Bilgel M, Resnick S, Beason-Held L, Landman BA, Li Z.   +11 more
europepmc   +1 more source

Generalizing the Gaussian Network Model: Spanning‐Tree Thermodynamics Shows Entropy‐Driven KRAS Activation

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The GTPase KRAS executes a conformational switch between a GTP‐bound active state and a GDP‐bound inactive state, a process central to oncogenic signaling. However, the structural basis of this switching at the level of residue‐contact organization remains incompletely characterized by traditional binary structural models.
Fatma Senguler Ciftci, Burak Erman
wiley   +1 more source

Hybrid framework for lesion-aware, clinically coherent chest X-ray report generation using contrastive learning and large language models. [PDF]

Sci Rep
Noh WJ, Pi SW, Lee BD.
europepmc   +1 more source

scMetaTraj: A Metabolism‐Centered Framework for Trajectory Inference in Single‐Cell Data

Med Research, EarlyView.
Jinwei Dai, Zhihong Zuo, Xiaoyang Pang, Lixin Ke, Lina Zhang, Zhaoxin Qian   +5 more
wiley   +1 more source

Microbiome‐mediated chemical communication in insects: Implications for pest management

Pest Management Science, EarlyView.
Microbiome–semiochemical interactions involve the following processes: direct microbial synthesis, host gene regulation, precursor biotransformation, microbiome modulation and indirect ecological signaling. Abstract Insects rely on semiochemicals to regulate aggregation, mating, foraging, and host selection. This review synthesizes evidence that insect‐
Ioannis Eleftherianos, Wei Zhang, Amr Mohamed, Rasha K. Al‐Akeel, Abeer M. Alkhaibari, Nemat Keyhani, Guy Smagghe   +6 more
wiley   +1 more source

Body Surface Area Indexing Attenuates Apparent Early eGFR Decline After Sleeve Gastrectomy: A Retrospective Cohort Study. [PDF]

J Clin Med
Cankaya E, Babaoglu H, Bayrakdar Çağlayan F, Karahisar Sirali S, Banli O, Demir ME, Dede F.   +6 more
europepmc   +1 more source

Analysis of C4 Concentrations to Predict Impact of Patient‐Reported Diarrhea Associated With the Ileal Bile Acid Transporter Inhibitor Linerixibat

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 596-605, March 2025.
ABSTRACT Linerixibat, an ileal bile acid transporter (IBAT) inhibitor, is being evaluated for the treatment of pruritus in primary biliary cholangitis (PBC). Diarrhea is commonly reported with this drug class as IBAT inhibition redirects bile acids (BA) to the colon.
Fernando Carreño, Rashmi Mehta, Andrea Ribeiro de Souza, Jon Collins, Brandon Swift   +4 more
wiley   +1 more source