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A blog post originally appearing on the Archive Stories WordPress site. The original site was created as a component of a funded pathway of the Andrew W.
Grand Challenges at Hope College, Mellon Foundation
core
The multifaceted roles of lysosomes in cancer
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley +1 more source
A blog post originally appearing on the Archive Stories WordPress site. The original site was created as a component of a funded pathway of the Andrew W.
Grand Challenges at Hope College, Mellon Foundation
core
Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau +9 more
wiley +1 more source
Grand challenges and future oral epidemiology research. [PDF]
Foláyan MO, Starr JR.
europepmc +1 more source
A blog post originally appearing on the Paris Stories WordPress site. The original site was created as a component of a funded pathway of the Andrew W. Mellon Foundation Grand Challenges Initiative of Hope College (Nations, Citizens, and Outsiders: Paris
Grand Challenges at Hope College, Mellon Foundation
core
Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up
This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani +7 more
wiley +1 more source
US-China science collaboration to solve global grand challenges. [PDF]
Beachy RN, Seto KC.
europepmc +1 more source

