Results 61 to 70 of about 26,886 (233)

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Secondary structure formation of homopolymeric single-stranded nucleic acids including force and loop entropy: implications for DNA hybridization

, 2011
Loops are essential secondary structure elements in folded DNA and RNA molecules and proliferate close to the melting transition. Using a theory for nucleic acid secondary structures that accounts for the logarithmic entropy c ln m for a loop of length m,
Einert, Thomas R., Netz, Roland R., Orland, Henri   +2 more
core   +1 more source

Paramagnetic Rim Lesions Are Associated With Trans‐Synaptic Degeneration of the Visual Pathway in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Retrograde trans‐synaptic degeneration (rTSD) from posterior visual pathway lesions in multiple sclerosis (MS) is characterized by hemi‐macular ganglion cell‐inner plexiform layer (GCIPL) thinning and contralateral visual field loss.
Abdul Jaber Tayem, Angel Liu, Sargis Manukyan, Mustafa Subhi, Elaina Luskin, Bryan Quah, Sreekanth Madhusoodhanan Nair, Arzu C. Has Silemek, Gabriela Zabala, Yujie Cui, Laura Locke, Paula Barreras, Marwa Kaisey, Vinicius Calsavara, Daniel S. Reich, Nancy L. Sicotte, Pascal Sati, Omar Al‐Louzi   +17 more
wiley   +1 more source

Finite size scaling in Ising-like systems with quenched random fields: Evidence of hyperscaling violation

, 2010
In systems belonging to the universality class of the random field Ising model, the standard hyperscaling relation between critical exponents does not hold, but is replaced by a modified hyperscaling relation. As a result, standard formulations of finite
Binder, K., Fischer, T., Vink, R. L. C.
core   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

On the Yang-Lee and Langer singularities in the O(n) loop model

, 2011
We use the method of `coupling to 2d QG' to study the analytic properties of the universal specific free energy of the O(n) loop model in complex magnetic field.
Fonseca P Zamolodchikov A, Ginsparg P H Moore G W, Ivan Kostov, Jean-Emile Bourgine, Kobzarev I Y, Kostov I, Mangazeev V V, Mossa A, Nienhuis B, Voloshin M B, Zamolodchikov A Zamolodchikov Al, Zamolodchikov Al   +11 more
core   +1 more source

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento, Daniela F. Santos, Tuane C. R. G. Vieira, Tiago F. Outeiro   +3 more
wiley   +1 more source

A model for nuclear matter fragmentation: phase diagram and cluster distributions

, 1998
We develop a model in the framework of nuclear fragmentation at thermodynamic equilibrium which can be mapped onto an Ising model with constant magnetization. We work out the thermodynamic properties of the model as well as the properties of the fragment
A. Tarancón, Bondorf, Borderie, Brézin, Campi, Coniglio, Dorso, Falcioni, Ferrenberg, Fisher, Fukugita, Gross, Gross, Gross, Hauger, J. Richert, J.M. Carmona, Kawasaki, Kertész, Lee, Ma, Metropolis, Pan, Pan, Pan, Pochodzalla, Richert, Schüttauf, Sokal, Stauffer, Zheng, Zinn-Justin   +31 more
core   +1 more source

Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro, Shiwen Koay, Gordon T. Ingle, Patricia McNamara, Laura Watson, Fion Bremner, Valeria Iodice   +6 more
wiley   +1 more source

Ferromagnetic phase transition in a Heisenberg fluid: Monte Carlo simulations and Fisher corrections to scaling

, 2000
The magnetic phase transition in a Heisenberg fluid is studied by means of the finite size scaling (FSS) technique. We find that even for larger systems, considered in an ensemble with fixed density, the critical exponents show deviations from the ...
A. L. Ferreira, B. U. Felderhof, B. U. Felderhof, C. Holm, D. Frenkel, E. Lomba, E. Martina, F. Lado, F. Schinagl, G. Orkoulas, H. G. Ballesteros, I. M. Mryglod, I. M. Mryglod, I. Mryglod, I. P. Omelyan, I. P. Omelyan, J. J. Weis, J. Kyriakidis, J. M. Tavares, J. Sak, K. Binder, K. Binder, K. Binder, K. Chen, L. Feijoo, M. E. Fisher, M. E. Fisher, M. J. P. Nijmeijer, M. J. P. Nijmeijer, M. J. P. Nijmeijer, M. Krech, M. N. Barber, P. C. Hemmer, P. de Smedt, R. F. Craknell, R. Folk, R. Folk, T. G. Sokolovska   +37 more
core   +1 more source