Results 51 to 60 of about 26,886 (233)

First-order phase transition and tricritical scaling behavior of the Blume-Capel model: a Wang-Landau sampling approach

, 2015
We investigate the tricritical scaling behavior of the two-dimensional spin-$1$ Blume-Capel model using the Wang-Landau method measuring the joint density of states for lattice sizes up to $48\times 48$ sites.
Jeong, Joohyeok, Kim, Dong-Hee, Kwak, Wooseop, Lee, Juhee   +3 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Coulomb blockade in metallic grains at large conductance

, 2002
We study Coulomb blockade effects in the thermodynamic quantities of a weakly disordered metallic grain coupled to a metallic lead by a tunneling contact with a large conductance $g_T$.
A. Furusaki, A. Kamenev, A. Kamenev, A. Kamenev, A. Kaminski, A. V. Andreev, A.V. Andreev, A.V. Andreev, C. Itzykson, E. Brezin, G. Schön, Harish-Chandra, I. S. Beloborodov, I.L. Aleiner, I.L. Aleiner, I.S. Beloborodov, J. Ambjorn, J.J. Duistermaat, J.J. Duistermaat, K. Flensberg, K.A. Matveev, S.E. Korshunov, S.F. Edwards, S.V. Panyukov, T. Guhr, V. Ambegaokar, V.N. Prigodin, V.N. Prigodin, W. Hofstetter, X. Wang, Y.V. Nazarov   +30 more
core   +1 more source

Exactly Solvable Models: The Road Towards a Rigorous Treatment of Phase Transitions in Finite Systems

, 2005
We discuss exact analytical solutions of a variety of statistical models recently obtained for finite systems by a novel powerful mathematical method, the Laplace-Fourier transform.
A. Chodos, A. Dillmann, C. N. Yang, C. N. Yang, C. S. Kiang, D. A. Liberman, D. H. E. Gross, D. Stauffer, D. Teaney, F. Gulminelli, G. D. Yen, J. P. Bondorf, K. A. Bugaev, K. A. Bugaev, K. A. Bugaev, K. A. Bugaev, K. A. Bugaev, K. A. Bugaev, K. A. Bugaev, K. Huang, L. Beaulieu, L. G. Moretto, L. G. Moretto, M. D’Agostino, M. E. Fisher, M. E. Fisher, M. E. Fisher, M. Gazdzicki, M. Gyulassy, M. I. Gorenstein, M. I. Gorenstein, M. I. Gorenstein, M. L. Gilkes, P. Chomaz, P. T. Reuter, Ph. Chomaz, R. B. Griffiths, R. Guida, R. P. Feynman, S. Gupta Das, T. L. Hill   +40 more
core   +2 more sources

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Dimension-Dependence of the Critical Exponent in Spherically Symmetric Gravitational Collapse

, 2005
We study the critical behaviour of spherically symmetric scalar field collapse to black holes in spacetime dimensions other than four. We obtain reliable values for the scaling exponent in the supercritical region for dimensions in the range $3.5\leq D ...
B Preston, G Kunstatter, Gundlach C, Husain V, Husain V, J Bland, Kunstatter G, Lehner L, M Becker, V Husain   +9 more
core   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Dependence of the BEC transition temperature on interaction strength: a perturbative analysis

, 2000
We compute the critical temperature T_c of a weakly interacting uniform Bose gas in the canonical ensemble, extending the criterion of condensation provided by the counting statistics for the uniform ideal gas. Using ordinary perturbation theory, we find
Arnold P, Baym G, Cruz F F, Fabrizio Illuminati, Fetter A, Grossmann S, Huang K, Illuminati F, Illuminati F, Krämer M, Martin Wilkens, Meret Krämer, Reppy J D, Stoof H, Toyoda T, Weiss C   +15 more
core   +1 more source