Results 81 to 90 of about 4,905,659 (296)
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Library of America Matching Grant Award to the Library 1985
Photo of the Library of America books awarded to the Roseland Library by matching grant 1985. Plaque from the Andrew Mellon Foundation to the Friends of the Roseland Library showing the matching grant award of the Library of America books ...
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α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
LoCoNOMA: A grant-free resource allocation for massive MTC
Massive machine-type communications (mMTC) represent a significant challenge in the fifth generation of wireless networks (5G) and become increasingly critical in the sixth generation (6G) due to the limited frequency spectrum. Addressing the demands of mMTC requires efficient resource sharing among multiple users.
Oueslati, Ibtissem +3 more
openaire +3 more sources
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Columbus Free Press newsletter
Newsletter sent to Columbus Free Press staff and volunteers, documenting the current financial status of the newspaper and relevant news. The Columbus Free Press began as a bi-weekly publication in Columbus, Ohio, in 1970.
Columbus Free Press (Publisher)
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This is a portrait of Grant Harris, owner of Cowtown Rodeo and Cowtown Flea Market. It was created as a part of the You're U.S. project (http://youreus.com/). Created by Emile Klein, You’re U.S.
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