Results 121 to 130 of about 4,217,946 (332)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
American Recovery and Reinvestment Act of 2009: Grant Application Information, Tips, and Thoughts [PDF]
, 2009 This Special Report identifies some of the key elements for grants under the American Recovery and Reinvestment Act of 2009 ("Act"), offers general tips that likely will be of interest to nonprofits applying for stimulus-fund grants, and highlights some ...
Ann Beltran, Tim Delaney
core
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Exploring Perceptions and Practices in Organizing University Scientific Research [PDF]
Ovidius University Annals: Economic Sciences Serieshe development of transdisciplinary projects, crucial in the context of the complex challenges facing society. The organization of scientific research must prioritize the human factor and involve establishing the departments involved in university ...
Cristian Marius Toma +2 more
doaj
Impact evaluation of business development grants on SME performance
Small Business Economics, 2020 Stjepan Srhoj, Michal Lapinski, J. Walde
semanticscholar +1 more source
Staffing for Adequate Fire and Emergency Response: The SAFER Grant Program [PDF]
, 2008 [Excerpt] In response to concerns over the adequacy of firefighter staffing, the Staffing for Adequate Fire and Emergency Response Act—popularly called the “SAFER Act”—was enacted by the 108th Congress as Section 1057 of the FY2004 National Defense ...
Kruger, Lennard G
core +22 more sources
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
The communication of public aid in the European Union: the case of Next Generation European funds
Communication & Society (Formerly Comunicación y Sociedad)In order to publicize the Next Generation funds (which will provide €806.9 billion in 2020 prices), each EU member state has had to create a portal that brings together all the information related to this instrument in accordance with the reference ...
Maria-J. Vilaplana-Aparicio +2 more
doaj +1 more source
Design for Giving: Understanding What Motivates Corporate Philanthropy [PDF]
, 2003 What motivates corporate philanthropy? Since corporate giving is often fragmented, both in the sense of where grants originate within a company and where they are distributed, corporations typically lack a clear and comprehensive picture of their overall
John Kania, Mindy W. Oakley
core
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source