Results 61 to 70 of about 1,850,789 (291)

NeuroSuite for Long‐Term Functional and Structural Studies of Air‐Liquid Interface Cerebral Organoids

Advanced Science, EarlyView.
NeuroSuite provides a modular hardware‐software platform integrating Neuroweb and NeuroMaps to enable long‐term, in situ electrophysiological interrogation of air–liquid interface organoid slices while preserving tissue architecture. Its components can be used together or independently to capture real‐time activity, spatial network dynamics, and ...
Belquis Haider, Sagnik Middya, Daniel J. Lloyd‐Davies‐Sánchez, Nino F. Läubli, Sulay Vora, Jakob Träuble, Rohan N. Krajeski, Yuqing Feng, Daniel Duncko, Josiah S. Riley, Rubén Ruiz‐Mateos Serrano, Ole Paulsen, Madeline A. Lancaster, George G. Malliaras, Gabriele S. Kaminski Schierle   +14 more
wiley   +1 more source

In Situ Genetic Engineering Facilitates MMP‐9‐Responsive TIMP1 Release Through Proteolytic Cleavage to Boost Diabetic Wound Healing

Advanced Science, EarlyView.
This study develops an MMP‐9‐responsive protein release system that transforms resident cells into drug depots through in situ genetic engineering. Anchored to the membrane, the therapeutic protein TIMP1 is selectively released upon MMP‐9 cleavage.
Yuan Zhang, Jiani Deng, Man Yee Cheung, Tingting Fu, Xufeng Qi, Dongqing Cai, Jianmin Sun, Gang Lu, Peng Shi, Wai‐Yee Chan, Xu Li, Hui Zhao   +11 more
wiley   +1 more source

Harmonizing Rigidity and Flexibility: Embedding COF Quantum Dots Into Extracellular Matrix Gel as Carbon Monoxide Depot for Acoustically Triggered Time‐Programmable Anti‐Infective Therapy

Advanced Science, EarlyView.
A rigid‑flexible integrated CO depot is engineered by embedding rigid COFQDs into a flexible ECM gel network. The rigid framework enables high‑capacity CO storage and sonodynamic bacterial killing, while the flexible ECM gel controls sustained CO release, collectively eradicating multidrug‑resistant infection and promoting scarless healing.
Baohong Sun, Fang Han, Chunxiao Zhu, Zhiyuan Yang, Haoru Wang, Jinpei Mei, Jie Chen, Jingwen Zhu, Zihan Bo, Taju Wu, Xiaogang Zhou, Tao Ma, Yutian Su, Youhui Lin   +13 more
wiley   +1 more source

STUDIES ON GRANULATION TISSUE

The Keio Journal of Medicine, 1960
A morphological and biochemical study of granulation tissue in wound healing was reported, using the circular excised wound of the dorsal skin of male adult mice.Argyrophilic fibrils appeared first on the 6th day after the excision. After the 8th and subsequent days, prominent fibrogenesis was marked. Ribonucleic acid was most intensely demonstrated on
openaire   +3 more sources

Microscopic images of granulation tissue.

, 2013
Tissue preparations were obtained on day 7. The thickness of granulation tissue (double-headed arrows) significantly increased in the normoxia group (A) as compared to the hypoxia group (B).
Naomi Sekiya (296855), Hitomi Sano (296853), Shigeru Ichioka (296854)   +2 more
core   +1 more source

Pyrazole‐Derived Antibacterial Compounds Effectively Treat Methicillin‐Resistant Staphylococcus Aureus Infections by Inhibiting Aspartate Transcarbamoylase

Advanced Science, EarlyView.
This study unveils a novel antibacterial mechanism against MRSA, in which the compound Py‐27 selectively targets and inhibits aspartate transcarbamoylase (ATCase), a key enzyme in pyrimidine synthesis. This inhibition disrupts DNA replication, induces oxidative damage, leading to potent bactericidal activity.
Xiaorong Yang, Xinyuan Cao, Lixia Dai, Feng Yang, Jing Wang, Yudong Ma, Tong Bu, Zile Gong, Xueyan Liu, Changcai Bai, Xiaolou Miao, Xiaofei Shang   +11 more
wiley   +1 more source

Study on the pathological diagnostic value of spinal tuberculosis lesions with different submitting methods and tissue types

Journal of Orthopaedic Surgery and Research
Objectives To investigate the pathological diagnostic value of spinal tuberculosis (STB) lesions with different submitting methods and tissue types, provide a reference for accurate submission of STB tissue specimens, and improve the accuracy of ...
HongBao Ma, XueWei Wang, ChaoRan Wang, CaiLi Lou, ZongQiang Yang, Ning Zhang, JianDang Shi, NingKui Niu   +7 more
doaj   +1 more source

Otoendoscope combined with ablation electrodes for treatment of benign tracheal stenosis caused by granulation tissue hyperplasia after tracheotomy

The Pan African Medical Journal, 2020
Benign tracheal stenosis mainly appears due to tracheotomy, tuberculosis, trauma, benign tumor, or ventilation. With the increase in the number of tracheotomies and the prolongation of the life span of patients after incision, the long-term complications
Laina Ndapewa Angula, Yongliang Teng, Le Sun, Xin Wang, Jing Shang, Ning Fang   +5 more
doaj   +1 more source

Combination of Shengji ointment and bromelain in the treatment of exposed tendons in diabetic foot ulcers: study protocol for a non-blind, randomized, positive control clinical trial

BMC Complementary Medicine and Therapies, 2023
Background Diabetic foot ulcers often affect tendon tissue. Consequently, the infection may spread proximally along the tendon, leading to amputation or even the death of patients.
Yang Zhao, Xinyue Dai, Xu Sun, Zhaohui Zhang, Hongyang Gao, Rui Gao   +5 more
doaj   +1 more source

Ultrasound‐Activated Piezoelectric Neuroimmune Hydrogel Orchestrates Neurogenesis‐Macrophage Crosstalk in Diabetic Wound Healing

Advanced Science, EarlyView.
In this work, we design an ultrasound‐activated piezoelectric hydrogel platform (AOEF@AP5+US) that reprograms neurogenesis‐macrophage crosstalk as an integrated strategy to overcome the intertwined barriers of chronic inflammation, peripheral neuropathy, and impaired regeneration in diabetic wounds.
Kai Wang, Shaowen Zhuo, Binyu Song, Jinan Chen, Xin Zhao, Sijia Li, Shuang You, Dong Jiang, Yuedong Chen, Juanli Dang, Tong Wang, Baolin Guo, Zhou Yu, Baoqiang Song   +13 more
wiley   +1 more source