Results 11 to 20 of about 99,140 (146)

Favorable response to pembrolizumab in granulocyte colony‐stimulating factor‐producing upper urinary tract urothelial carcinoma

IJU Case Reports, 2022
Introduction Granulocyte colony‐stimulating factor‐producing upper urinary tract urothelial carcinoma is rare, with a poor prognosis. Advanced urothelial carcinoma is currently treated with immune checkpoint inhibitors, whose efficacy for granulocyte ...
Hiroki Takeda, Ryuji Matsumoto, Emi Takakuwa, Kanta Hori, Takuya Moriguchi, Shuhei Yamada, Hiroshi Kikuchi, Takahiro Osawa, Takashige Abe, Nobuo Shinohara   +9 more
doaj   +1 more source

Granulocyte-macrophage colony-stimulating factor increases tumor growth and angiogenesis directly by promoting endothelial cell function and indirectly by enhancing the mobilization and recruitment of proangiogenic granulocytes

Tumor Biology, 2017
Granulocyte-macrophage colony-stimulating factor has been widely used as an adjuvant therapy for cancer patients exhibiting myelosuppression induced by chemotherapy or radiotherapy. However, the effects of granulocyte-macrophage colony-stimulating factor
Qiaowei Zheng, Xueqian Li, Xiaoliang Cheng, Ting Cui, Yingcheng Zhuo, Wenbin Ma, Xue Zhao, Peipei Zhao, Xuanlin Liu, Weiyi Feng   +9 more
doaj   +1 more source

The Potential Role of Recombinant Hematopoietic Colony-Stimulating Factors in Preventing Infections in the Immunocompromised Host

Canadian Journal of Infectious Diseases, 1991
Hematopoietic colony-stimulating factors coordinate the proliferation and maturation of bone marrow and peripheral blood cells during normal hematopoiesis.
James Rusthoven
doaj   +1 more source

Dexamethasone and granulocyte colony-stimulating factor alter the representation of cellular patterns and neurotisation of regenerative neuroma

Patologìâ, 2023
Aim. To evaluate the changes in the total cellularity (Nuc) of the rat sciatic nerve regenerative neuroma (RegN) and its representation of CD90, CD44, CD146, and CD133 positive cells, as well as its neurotization under the conditions of dexamethasone ...
O. M. Grabovyi, N. M. Nevmerzhytska, O. B. Alyokhin, H. B. Kostynskyi, H. Yu. Kondaurova   +4 more
doaj   +1 more source

Granulocyte Colony-Stimulating Factor [PDF]

, 2020
Granulocyte colony-stimulating factor was discovered during attempts to define the normal regulators present in cell supernatants that could induce terminal differentiation of the murine myeloid leukemic cell line WEHI-3B D+. The purification and subsequent cloning of both murine and human G-CSF allowed the normal functions of this molecule to be ...
Andrew W. Roberts, Nicos A. Nicola
openaire   +2 more sources

Heparan sulfate mimetics can efficiently mobilize long-term hematopoietic stem cells

Haematologica, 2012
Background Although mobilization of hematopoietic stem cells and hematopoietic progenitor cells can be achieved with a combination of granulocyte colony-stimulating factor and plerixafor (AMD3100), improving approaches for hematopoietic progenitor cell ...
Fabio Di Giacomo, Daniel Lewandowski, Eric Cabannes, Vanessa Nancy-Portebois, Maurice Petitou, Serge Fichelson, Paul-Henri Romeo   +6 more
doaj   +1 more source

Follow-up of healthy donors receiving granulocyte colony-stimulating factor for peripheral blood progenitor cell mobilization and collection. Results of the Spanish Donor Registry

Haematologica, 2008
Background Information about the long-term follow-up and safety of granulocyte colony-stimulating factor administration to healthy donors is limited.
Javier de la Rubia, Felipe de Arriba, Cristina Arbona, María J. Pascual, Concha Zamora, Andrés Insunza, Dorleta Martínez, Carmen Paniagua, Miguel A. Díaz, Miguel A. Sanz   +9 more
doaj   +1 more source

Failure of granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor in a patient with Kostmann syndrome

The Turkish Journal of Pediatrics, 1999
We present a seven-month-old boy referred to our hospital with a history of recurrent suppurative infections starting in his neonatal period. Anemia, absolute neutropenia absolute neutrophil count (ANC: 500 cells/pl), pneumonia, purulent otitis media ...
Volkan Hazar, Hakan Ongun, M. Akif Yeşilipek, Olcay Yeğin   +3 more
doaj   +1 more source

G‐CSF/GM‐CSF‐induced hematopoietic dysregulation in the progression of solid tumors

FEBS Open Bio, 2022
There are two types of abnormal hematopoiesis in solid tumor occurrence and treatment: pathological hematopoiesis, and myelosuppression induced by radiotherapy and chemotherapy. In this review we primarily focus on the abnormal pathological hematopoietic
Kai He, Xi Liu, Robert D. Hoffman, Rong‐Zhen Shi, Gui‐Yuan Lv, Jian‐Li Gao   +5 more
doaj   +1 more source

Potentiation of Lupus Activity by Granulocyte Colony-Stimulating Factor

Journal of Clinical Rheumatology and Immunology, 2021
Recombinant human granulocyte colony-stimulating factor (G-CSF) is commonly used to accelerate recovery of neutropenia in patients with marrow suppression.
Tsz Ching Mok, Lok Ping Ng, Eva Tsz Fung Chui, Ho Yin Chung   +3 more
doaj   +1 more source