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Granulocyte-Macrophage Colony-stimulating Factor
Biotherapy, 1990Publisher Summary Granulocyte-macrophage colony-stimulating factor (GM-CSF) is one of the four classical colony-stimulating factors discovered in the 1960s following the introduction of semi-solid bone-marrow culture techniques. The human GM-CSF gene is located on chromosome 5 (q25–q31) within 10 kb of the interleukin-3 (IL-3) gene and in the same ...
S, Devereux, D C, Linch
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Functions of Granulocyte-Macrophage Colony-Stimulating Factor
Critical Reviews in Immunology, 2005GM-CSF was originally defined by its ability to generate in vitro granulocyte and macrophage colonies from bone marrow precursor cells. Apart from its physiological role in the control of alveolar macrophage development, it now appears more likely that its major role lies in its ability to govern the properties of the more mature myeloid cells of the ...
Andrew J, Fleetwood +2 more
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Granulocyte-Macrophage Colony-Stimulating Factor in Psoriasis
Dermatologica, 2009Granulocyte-macrophage colony-stimulating factor (GM-CSF), a product of activated T lymphocytes, macrophages, endothelial cells, fibroblasts, and keratinocytes, is thought to play an important role in inflammatory reactions by ‘priming’ or enhancing the functions of neutrophils and macrophages.
H, Takematsu, H, Tagami
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Granulocyte-macrophage colony-stimulating factor
International Archives of Allergy and Applied Immunology, 2009Granulocyte-macrophage colony-stimulating factor (GM-CSF) is a well-characterized hematopoietic growth factor. Recently, using purified recombinant-derived material, we have found that GM-CSF is also a potent activator of mature functional macrophages.
Maryann Foote, George Morstyn
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Granulocyte-Macrophage Colony-Stimulating Factor
Journal of Pediatric Oncology Nursing, 1991D L, Betcher, N, Burnham
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The Granulocyte-Macrophage Colony-Stimulating Factors
Science, 1985The granulocyte-macrophage colony-stimulating factors are well-characterized specific glycoproteins that interact to control the production, differentiation, and function of two related white cell populations of the blood, the granulocytes and monocyte-macrophages.
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The Granulocyte-Macrophage Colony-Stimulating Factors
1986Haemopoiesis is the process whereby a small population of multipotential stem cells continuously gives rise to a large number of mature blood cells which comprise eight distinct cellular lineages. In normal health, the circulating levels of mature cells are remarkably invariant, suggesting that their production is tightly regulated.
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