Results 21 to 30 of about 73,450 (245)

Effect of granulocyte macrophage colony stimulating factor on treatment of acute osteomyelitis

Acta Orthopaedica et Traumatologica Turcica, 2021
Granulocyte macrophage-colony stimulating factor (GM-CSF) is a cytokine which effects the various developmental steps of hematopoietic cells and enhances the phagocytic activity of these cells.
Ahmet Kapukaya, Mehmet Subasi, Halil Kaya, Cumhur Kesemenli, Ibrahim Sari, Engin Kandiya   +5 more
doaj  

Immune Evasion of G-CSF and GM-CSF in Lung Cancer [PDF]

Tuberculosis and Respiratory Diseases
Tumor immune evasion is a complex process that involves various mechanisms, such as antigen recognition restriction, immune system suppression, and T cell exhaustion.
Yeonhee Park, Chaeuk Chung
doaj   +1 more source

Single‐Cell Mechanical Characterization of Human Macrophages

Advanced NanoBiomed Research, 2022
Macrophages remodel their mechanics during differentiation toward different subtypes and drastically adapt their shapes during phagocytosis or entry to inflamed tissues.
Tom M. J. Evers, Vahid Sheikhhassani, Huaqi Tang, Mariëlle C. Haks, Tom H. M. Ottenhoff, Alireza Mashaghi   +5 more
doaj   +1 more source

AIF1+CSF1R+ MSCs, induced by TNF‐α, act to generate an inflammatory microenvironment and promote hepatocarcinogenesis

Hepatology, EarlyView., 2022
Mesenchymal stem cells subset, educated by TNF‐α, are involved to generate inflammatory microenvironment and promote hepatocarcinogenesis Abstract Background and Aims Increasing evidence suggests that mesenchymal stem cells (MSCs) home to injured local tissues and the tumor microenvironment in the liver.
Chen Zong, Yan Meng, Fei Ye, Xue Yang, Rong Li, Jinghua Jiang, Qiudong Zhao, Lu Gao, Zhipeng Han, Lixin Wei   +9 more
wiley   +1 more source

Application of Western Blot for detection of neutrophil apoptosis-related proteins

Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2009
The aim of this study was to evaluate suitability of using Western Blot for detection of neutrophil apo­pto­sis and neutrophil apoptosis-related proteins, respectively. Neutrophils were isolated from blood of healthy adult donors and incubated with G-CSF
Petr Sláma
doaj   +1 more source

Saharan dust induces the lung disease-related cytokines granulocyte–macrophage colony-stimulating factor and granulocyte colony-stimulating factor

Environment International
Desert dust exposure is associated with adverse respiratory health effects. Desert dust is a complex pollutant mixtures that includes respirable crystalline and amorphous particles, metals, and microbial constituents.
Gerrit Bredeck, Jochen Dobner, Andrea Rossi, Roel P.F. Schins   +3 more
doaj   +1 more source

Factores de Crescimento Hematopoiético

Revista Portuguesa de Pneumologia, 1995
SUMÁRIO: Os factores de crescimento hematopoiético (FCH) são glicoproteinas que regulam a proliferação e diferenciação das células sanguíneas.
Maria De Fátima Miguel Rodrigues, Margarida Cristóvão, Agostinho Costa, M.a José Melo   +3 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Granulocyte macrophage colony stimulating factor (GM-CSF) biological actions on human dermal fibroblasts

European Journal of Histochemistry, 2009
Fibroblasts are involved in all pathologies characterized by increased ExtraCellularMatrix synthesis, from wound healing to fibrosis. Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) is a cytokine isolated as an hemopoietic growth factor but ...
S Montagnani, L Postiglione, G Giordano-Lanza, F Di Meglio, C Castaldo, S Sciorio, N Montuori, G Di Spigna, P Ladogana, A Oriente, G Rossi   +10 more
doaj   +1 more source