Tutorial for Modeling Delays in Biological Systems in the NONMEM Software
ABSTRACT Delays in biological systems are a common phenomenon. The models for delays require specialized mathematical and numerical techniques such as transit compartments, delay differential equations (DDEs), and distributed DDEs (DDDEs). Because of mathematical complexity, DDEs and particularly DDDEs are infrequently used for modeling.
Robert J. Bauer, Wojciech Krzyzanski
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Granulocyte colony-stimulating factor-associated aortitis in a man with advanced prostate cancer. [PDF]
Ikadai R, Kitano G, Kato M, Kojima T.
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Potential roles of antibodies with different classes in IgG4‐related diseases
This review discussed the common characteristics of different classes of antibodies and their potential corresponding unique mechanisms involved in immunoglobulin G4‐related disease. Abstract Immunoglobulin G4‐related disease (IgG4‐RD), first identified two decades ago, is an immune‐mediated pro‐inflammatory and profibrotic disease entity affecting ...
Ling Li+6 more
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Effects of different granulocyte colony stimulating factor regimens on patients with euploid embryo transfer in recurrent implantation failure. [PDF]
Karaosmanoglu O+6 more
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THE REGULATORY ROLE OF DIVALENT CATIONS IN HUMAN GRANULOCYTE CHEMOTAXIS
John I. Gallin, Alan S. Rosenthal
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Neut‐GI and Re‐Lymp levels correlated with changes in SLEDAl‐2K scores. Specifically, increasing in SLEDAl‐2K scores was associated with decreasing in extended inflammatory parameters. Thus, Neut‐Gland Re‐Lymp might serve as simpler and more cost‐effective alternatives to SLEDAI‐2K scores for monitoring changes in SLE activity.
Galuh Setyorini+5 more
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This review explores the potential of antimicrobial peptides (AMPs) and nanotechnology for the treatment of gastrointestinal infections. It analyzes bacterial resistance mechanisms, the antimicrobial actions of AMPs, and advances in nanocarriers, such as lipid‐based, polymeric, metallic, and mesoporous silica systems, that enhance peptide protection ...
Christian Shleider Carnero Canales+10 more
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Gastric dilatation and volvulus in a capybara (Hydrochoerus hydrochaeris, Linnaeus, 1766)
Abstract Gastric torsion has been described in several species, but this is the first documented case in a capybara. An entire, 6‐year‐old, female capybara was found dead in the indoor enclosure of the zoo in the morning. Pathological examinations revealed a large, bloated stomach upon opening the abdominal cavity.
Anna Linda Nógrádi+3 more
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Propylthiouracil-induced ANCA-associated vasculitis complicated by granulocytopenia and hemophagocytosis: a case report. [PDF]
Zhou H+5 more
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Maternal Immune Activation During Pregnancy and Obstetric Outcomes: A Population‐Based Cohort Study
ABSTRACT Objective Maternal immune activation has been proposed as a mechanism for adverse pregnancy outcomes, yet the mechanisms and effects of timing remain unclear. Immune disruption in early gestation may be particularly detrimental as this is an important period for placental development, which has been associated with the pathology of adverse ...
Frederieke A. J. Gigase+10 more
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