Results 51 to 60 of about 369,640 (388)

Interaction of drug- and granulocyte-mediated killing of Pseudomonas aeruginosa in a murine pneumonia model.

Journal of Infectious Diseases, 2014
BACKGROUND Killing of bacterial pathogens by granulocytes is a saturable process, as previously demonstrated. There is virtually no quantitative information about how granulocytes interact with antimicrobial chemotherapy to kill bacterial cells ...
G. Drusano, Weiguo Liu, Steven Fikes, R. Cirz, Nichole Robbins, Stephanie Kurhanewicz, J. Rodriquez, David Brown, Dodge Baluya, A. Louie   +9 more
semanticscholar   +1 more source

FcγRIIIb Restricts Antibody-Dependent Destruction of Cancer Cells by Human Neutrophils

Frontiers in Immunology, 2019
The function of the low-affinity IgG-receptor FcγRIIIb (CD16b), which is uniquely and abundantly expressed on human granulocytes, is not clear. Unlike the other Fcγ receptors (FcγR), it is a glycophosphatidyl inositol (GPI) -anchored molecule and does ...
Louise W. Treffers, Michel van Houdt, Christine W. Bruggeman, Marieke H. Heineke, Xi Wen Zhao, Joris van der Heijden, Sietse Q. Nagelkerke, Sietse Q. Nagelkerke, Paul J. J. H. Verkuijlen, Judy Geissler, Suzanne Lissenberg-Thunnissen, Thomas Valerius, Matthias Peipp, Katka Franke, Robin van Bruggen, Taco W. Kuijpers, Taco W. Kuijpers, Marjolein van Egmond, Gestur Vidarsson, Hanke L. Matlung, Timo K. van den Berg, Timo K. van den Berg   +21 more
doaj   +1 more source

Secretory Leukocyte Protease Inhibitor Is Present in Circulating and Tissue-Recruited Human Eosinophils and Regulates Their Migratory Function

Frontiers in Immunology, 2022
Eosinophils and secretory leukocyte protease inhibitor (SLPI) are both associated with Th2 immune responses and allergic diseases, but whether the fact that they are both implicated in these conditions is pathophysiologically related remains unknown ...
Oktawia Osiecka, Joanna Skrzeczynska-Moncznik, Agnieszka Morytko, Angelika Mazur, Pawel Majewski, Bernadetta Bilska, Monika Kapinska-Mrowiecka, Joanna Kosalka-Wegiel, Joanna Kosalka-Wegiel, Maciej Pastuszczak, Elzbieta Pyza, Joanna Cichy   +11 more
doaj   +1 more source

Lymphoid/nonlymphoid compartmentalization of donor leukocyte chimerism in rat recipients of heart allografts, with or without adjunct bone marrow [PDF]

, 1998
Background. The role of leukocyte migration and chimerism in organ allograft acceptance has been obscured by the lack of information about the late localization of the donor cells. Methods.
Demetris, AJ, Murase, N, Starzl, TE, Terakura, M, Thomson, AW, Ye, Q   +5 more
core   +1 more source

Mice lacking granulocyte colony-stimulating factor have chronic neutropenia, granulocyte and macrophage progenitor cell deficiency, and impaired neutrophil mobilization.

Blood, 1994
Mice lacking granulocyte colony-stimulating factor (G-CSF) were generated by targeted disruption of the G-CSF gene in embryonal stem cells. G-CSF-deficient mice (genotype G-CSF-/-) are viable, fertile, and superficially healthy, but have a chronic ...
G. Lieschke, D. Grail, G. Hodgson, D. Metcalf, E. Stanley, C. Cheers, K. Fowler, Sunanda Basu, Yi F. Zhan, A. Dunn   +9 more
semanticscholar   +1 more source

Dendritic Cell Activating Receptor 1 (DCAR1) Associates With FcεRIγ and Is Expressed by Myeloid Cell Subsets in the Rat

Frontiers in Immunology, 2019
Dendritic cell activating receptor-1 (DCAR1) is a cell-surface receptor encoded by the Antigen Presenting Lectin-like gene Complex (APLEC). We generated a mouse monoclonal antibody against rat DCAR1, and used this to characterize receptor expression and ...
Michael R. Daws, Britt Nakken, Ana Lobato-Pascual, Régis Josien, Régis Josien, Erik Dissen, Sigbjørn Fossum   +6 more
doaj   +1 more source

Effect of fungicidal contamination on survival, morphology, and cellular immunity of Apis mellifera (Hymenoptera: Apidae)

Frontiers in Physiology, 2023
Pesticide residues have been reported in hive-stored products for long periods. Larvae of honey bees experience oral or contact exposure to these products during their normal growth and development inside the cells.
Gurleen Kaur, Amandeep Singh, Rohit Sharma, Abhinay Thakur, Shushant Tuteja, Shyamli, Randeep Singh   +6 more
doaj   +1 more source

Glucose Homeostasis in Relation to Neutrophil Mobilization in Smokers with COPD

International Journal of COPD, 2022
Nikolaos Pournaras,1,2 Anders Andersson,3,4 Melissa A Kovach,1 Médea Padra,5 Karlhans F Che,1,2 Bettina Brundin,1 Shigemi Yoshihara,6 Steven Bozinovski,7 Sara K Lindén,5 Per-Anders Jansson,8 Magnus C Sköld,2,9 Ingemar Qvarfordt,3,8 Anders Lindén1,2 ...
Pournaras N, Andersson A, Kovach MA, Padra M, Che KF, Brundin B, Yoshihara S, Bozinovski S, Lindén SK, Jansson PA, Sköld MC, Qvarfordt I, Lindén A   +12 more
doaj  

Histone demethylase Lsd1 represses hematopoietic stem and progenitor cell signatures during blood cell maturation

eLife, 2013
Here, we describe that lysine-specific demethylase 1 (Lsd1/KDM1a), which demethylates histone H3 on Lys4 or Lys9 (H3K4/K9), is an indispensible epigenetic governor of hematopoietic differentiation. Integrative genomic analysis, combining global occupancy
Marc A Kerenyi, Zhen Shao, Yu-Jung Hsu, Guoji Guo, Sidinh Luc, Kassandra O'Brien, Yuko Fujiwara, Cong Peng, Minh Nguyen, Stuart H Orkin   +9 more
doaj   +1 more source

CEACAM3—A Prim(at)e Invention for Opsonin-Independent Phagocytosis of Bacteria

Frontiers in Immunology, 2020
Phagocytosis is one of the key innate defense mechanisms executed by specialized cells in multicellular animals. Recent evidence suggests that a particular phagocytic receptor expressed by human polymorphonuclear granulocytes, the carcinoembryonic ...
Patrizia Bonsignore, Johannes W. P. Kuiper, Jonas Adrian, Griseldis Goob, Christof R. Hauck, Christof R. Hauck   +5 more
doaj   +1 more source