Results 31 to 40 of about 116,398 (264)

Granulocyte Colony-Stimulating Factor-Producing Bladder Cancer

Case Reports in Oncology, 2019
Granulocyte colony-stimulating factor (G-CSF)-producing bladder cancer is rare, with only 75 cases reported in Japan. A 67-year-old woman was referred to our institution for the further examination of gross hematuria.
Ryota Morinaga, Takashi Kawahara, Shinnosuke Kuroda, Yoshiaki Inayama, Hiroji Uemura   +4 more
doaj   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Granulocyte Colony-stimulating Factor Producing Oropharyngeal Squamous Cell Carcinoma

, 2021
CASE REPORT We report on the case of a 47-year old woman with granulocyte colony-stimulating factor (G-CSF)-producing relapsed oropharyngeal squamous cell cancer. Palliative immunotherapy with nivolumab was started.
GREGORY SCHURMANN, TILMAN T. RAU, YOJENA KURIAN, Vinzens, Sarah, ROLAND GIGER, Schurmann, Gregory, Kurian, Yojena, Giger, Roland, MATTHIAS S. DETTMER, Dettmer, Matthias S, Zweifel, Martin, Rau, Tilman T, MARTIN ZWEIFEL, SARAH VINZENS   +13 more
core   +1 more source

Granulocyte-colony stimulating factor producing rectal cancer

World Journal of Surgical Oncology, 2008
Background Granulocyte-colony stimulating factor (G-CSF)-producing cancer has been reported to occur in various organs, especially the lung. However, G-CSF-producing colorectal cancer (CRC) has never been reported in the English literature.
Satoh Mikinori, Sawai Hirozumi, Funahashi Hitoshi, Wakasugi Takehiro, Takayama Satoru, Sakamoto Masaki, Ochi Nubuo, Yasuda Akira, Takahashi Hiroki, Akamo Yoshimi, Takeyama Hiromitsu   +10 more
doaj   +1 more source

A Long‐Lived Human Neurovascular PENTA Culture Model Captures Incomplete Vascular Repair and Glia‐Associated Signaling After Traumatic Brain Injury

Advanced Healthcare Materials, EarlyView.
A long‐lived, five‐cell‐type human neurovascular (PENTA) model recreates vascular disorganization and incomplete repair after traumatic brain injury (TBI). By integrating endothelial, glial, neuronal, and immune components within a 3D scaffold, the platform enables time‐resolved analysis of neurovascular remodeling and provides a human‐relevant system ...
Daniel S. Hinrichsen, Sunghyun Jun, Colleen M. Arrasmith, Charitha C. Anamala, Mitchell D. Thielen, Anapaula Garcia, Volha Liaudanskaya   +6 more
wiley   +1 more source

The novel CXCR4 antagonist POL5551 mobilizes hematopoietic stem and progenitor cells with greater efficiency than Plerixafor

, 2013
Mobilized blood has supplanted bone marrow (BM) as the primary source of hematopoietic stem cells for autologous and allogeneic stem cell transplantation.
Dembowsky, K., Dembowsky, Klaus, Romagnoli, B., G Spohn, Karpova, Darja, Patel, K., Chevalier, E., Levesque, J. P., E Chevalier, D Karpova, Patel, Kalpana, Spohn, Gabriele, Romagnoli, Barbara, Schulz, M., Wiercinska, Eliza, Chevalier, Eric, H Bonig, K Dauber, E Wiercinska, J P Levesque, Schulz, Miriam, Chudziak, D., K Dembowsky, Dauber, Katrin, Karpova, D., B Romagnoli, A R Pettit, Wiercinska, E., D Chudziak, Levesque, Jean-Pierre, Bönig, Halvard-Björn, Spohn, G., Pettit, Allison R., M Schulz, K Patel, Bonig, H., Pettit, A. R., Chudziak, Doreen, Dauber, K.   +38 more
core   +1 more source

Mesenchymal Stromal Cell‐Mediated Intercellular Communication: Mapping the Interactome for Skeletal Muscle Homeostasis and Regeneration

Advanced Science, EarlyView.
Liu et al. define a systems‐level interactome of fibroadipogenic progenitor (FAP)‐mediated signaling in skeletal muscle by integrating single‐cell transcriptomics with FAP depletion‐based perturbation analysis. Functional interrogation using a conditioned media bioassay links predicted signaling to multicellular outcomes, establishing a framework to ...
Xingyu Liu, Edgar E. Perez Carbajal, Yih‐Chii Hwang, Sahil A. Mapkar, Benjamin W. Gilman, Sarah A. Bliss, Lam B. Tran, Kalgi T. Mehta, Jacob O. Banyasz, Ming Yu, Reynold R. Liu, Matthew N. Ly, Christapher S. Morrissey, Michael N. Wosczyna   +13 more
wiley   +1 more source

A study of ovarian cancer patients treated with dose-intensive chemotherapy supported with peripheral blood progenitor cells mobilised by filgrastim and cyclophosphamide

, 1996
Summary We have shown that large numbers of haemopoietic progenitor cells are mobilised into the blood after filgrastim [granulocyte colony-stimulating factor (G-CSF)] alone and filgrastim following cyclophosphamide chemotherapy in previously untreated
Dexter, TM, C Gill, D Crowther, Gill, C, NG Testa, Weaver, A, Testa, NG, A Weaver, B Jenkins, R Pettengell, Collins, CD, Crowther, D, A Watson, Pettengell, R, Wrigley, E, J Chang, TM Dexter, Watson, A, CD Collins, E Wrigley, Chang, J, Jenkins, B   +21 more
core   +1 more source

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng   +17 more
wiley   +1 more source

Impact of constitutional polymorphisms in VCAM1 and CD44 on CD34+ cell collection yield after administration of granulocyte colony-stimulating factor to healthy donors

Haematologica, 2011
Background The number of CD34+ cells mobilized from bone marrow to peripheral blood after administration of granulocyte colony-stimulating factor varies greatly among healthy donors.
Beatriz Martín-Antonio, Magdalena Carmona, Jose Falantes, Encarnación Gil, Alicia Baez, María Suarez, Pedro Marín, Ildefonso Espigado, Álvaro Urbano-Ispizua   +8 more
doaj   +1 more source