Results 11 to 20 of about 4,628,372 (257)

Granulocyte colony‐stimulating factor and leukemogenesis [PDF]

Mediators of Inflammation, 2004
THE granulocyte colony‐stimulating factor (G‐CSF) plays an important role in normal granulopoiesis. Its functions are mediated by specific receptors on the surface of responsive cells and, upon ligand binding, several cytoplasmic tyrosine kinases are activated.
Lorena Lobo de Figueiredo, Rodrigo Siqueira de Abreu e Lima, Eduardo Magalhães Rego   +2 more
openaire   +3 more sources

Correlation between granulocyte colony-stimulating factor and the Notch signaling pathway in ischemic brain injury

, 2021
Introduction This study aimed to determine the relationship between granulocyte colony-stimulating factor (G-CSF) and the Notch signaling pathway in ischemic brain injury.
Ning Xie, Qin Huang, Wenyuan Xu, Jingting Han   +3 more
core   +1 more source

A randomised trial of granulocyte-macrophage colony-stimulating factor for neonatal sepsis: outcomes at 2 years [PDF]

, 2012
The authors performed a randomised trial in very preterm small-for-gestational age (SGA) babies to determine if prophylaxis with granulocyte-macrophage colony-stimulating factor (GM-CSF) improves outcomes (the PROGRAMS trial).
Carr, R., Robert Carr, Caroline Dore, Redshaw, ME, Petrou, Stavros, Marlow, N, Cowan, Frances M, Marlow, Neil, Nishma Patel, Neil Marlow, Timothy Morris, Dore, C., Carr, Robert, Maggie E Redshaw, Redshaw, M. E., Brocklehurst, P., Modi, N., Redshaw, Margaret, Redshaw, Maggie E., Patel, N., Morris, T., Peter Brocklehurst, Petrou, S, Stavros Petrou, Carr, R, Modi, Neena, Modi, N, Brocklehurst, Peter, Cowan, FM, Patel, Nishma, Morris, Timothy, Neena Modi, Morris, T, Dore, C, Frances M Cowan, Brocklehurst, P, Cowan, F. M., Cowan, Frances M., Patel, N, Dore, Caroline   +39 more
core   +1 more source

Granulocyte colony-stimulating factors for febrile neutropenia prophylaxis following chemotherapy : systematic review and meta-analysis [PDF]

, 2011
Background: Febrile neutropenia (FN) occurs following myelosuppressive chemotherapy and is associated with morbidity, mortality, costs, and chemotherapy reductions and delays.
Akehurst Ron L, Cooper, K. (Katy), Ph. D., Whyte, Sophie, Whyte Sophie, Akehurst, R.L., Madan, Jason, Akehurst, Ron L., Madan, J., Whyte, S., Madan Jason, Katy L Cooper, Cooper, K.L., Jason Madan, Ron L Akehurst, Stevenson Matt D, Sophie Whyte, Stevenson, M. (Matt), Cooper Katy L, Stevenson, M.D., Matt D Stevenson   +19 more
core   +2 more sources

Granulocyte-activating mediators (GRAM) [PDF]

, 1987
In the present study we investigated the capability of human epidermal cells to generate granulocyte-activating mediators (GRAM). It could be shown that human epidermal cells as well as an epidermoid carcinoma cell line (A431) produce an epidermal cell ...
Kapp, A., Zeck-Kapp, G., Möller, A., Putz, Reinhard, A. Kapp, E. Sch�pf, T. A. Luger, C. Hauser, M. Danner   +8 more
core   +1 more source

Granulocyte-Colony Stimulating Factor-Producing Pancreatic Adenosquamous Carcinoma Showing Aggressive Clinical Course [PDF]

, 2009
Herein, we encountered an 89-year-old woman with pancreatic cancer who presented with fever without infective focus, leukocytosis of 45,860/mu L, and elevation of serum granulocyte-colony stimulating factor (G-CSF).
Kamijo, Atsushi, Furuta, Kiyoshi, Joshita, Satoru, Matsubayashi, Kiyoshi, Miyabayashi, Hideharu, Sugiyama, Yukiko, Nakazawa, Koh, Kitano, Kiyoshi, Kawa, Shigeyuki   +8 more
core   +1 more source

The novel CXCR4 antagonist POL5551 mobilizes hematopoietic stem and progenitor cells with greater efficiency than Plerixafor [PDF]

, 2013
Mobilized blood has supplanted bone marrow (BM) as the primary source of hematopoietic stem cells for autologous and allogeneic stem cell transplantation.
Dembowsky, K., Dembowsky, Klaus, Romagnoli, B., G Spohn, Karpova, Darja, Patel, K., Chevalier, E., Levesque, J. P., E Chevalier, D Karpova, Patel, Kalpana, Spohn, Gabriele, Romagnoli, Barbara, Schulz, M., Wiercinska, Eliza, Chevalier, Eric, H Bonig, K Dauber, E Wiercinska, J P Levesque, Schulz, Miriam, Chudziak, D., K Dembowsky, Dauber, Katrin, Karpova, D., B Romagnoli, A R Pettit, Wiercinska, E., D Chudziak, Levesque, Jean-Pierre, Bönig, Halvard-Björn, Spohn, G., Pettit, Allison R., M Schulz, K Patel, Bonig, H., Pettit, A. R., Chudziak, Doreen, Dauber, K.   +38 more
core   +1 more source

A study of ovarian cancer patients treated with dose-intensive chemotherapy supported with peripheral blood progenitor cells mobilised by filgrastim and cyclophosphamide [PDF]

, 1996
Summary We have shown that large numbers of haemopoietic progenitor cells are mobilised into the blood after filgrastim [granulocyte colony-stimulating factor (G-CSF)] alone and filgrastim following cyclophosphamide chemotherapy in previously untreated
Dexter, TM, C Gill, D Crowther, Gill, C, NG Testa, Weaver, A, Testa, NG, A Weaver, B Jenkins, R Pettengell, Collins, CD, Crowther, D, A Watson, Pettengell, R, Wrigley, E, J Chang, TM Dexter, Watson, A, CD Collins, E Wrigley, Chang, J, Jenkins, B   +21 more
core   +1 more source

G-CSF Prevents the Progression of Structural Disintegration of White Matter Tracts in Amyotrophic Lateral Sclerosis: A Pilot Trial [PDF]

, 2011
Background: The hematopoietic protein Granulocyte-colony stimulating factor (G-CSF) has neuroprotective and regenerative properties. The G-CSF receptor is expressed by motoneurons, and G-CSF protects cultured motoneuronal cells from apoptosis.
Tobias Warnecke, Schneider, A, Deppe Michael, Floel, A, Thomas Duning, Harald Kugel, Mohammadi Siawoosh, Katja Kolpatzik, Knecht Stefan, Schiffbauer, H, Wolf Rüdiger Schäbitz, Hagen Schiffbauer, Schäbitz Wolf Rüdiger, Duning Thomas, Kugel Harald, Knecht, S, Warnecke Tobias, Agnes Floel, Kolpatzik, K, Warnecke, T, Floel Agnes, Kugel, H, Schabitz, WR, Deppe, M, Kolpatzik Katja, Armin Schneider, Mohammadi, S, Michael Deppe, Duning, T, Schneider Armin, Stefan Knecht, Siawoosh Mohammadi, Schiffbauer Hagen   +32 more
core   +1 more source

Granulocyte-colony stimulating factor in experimental stroke and its effects on infarct size and functional outcome: a systematic review [PDF]

, 2009
Background Granulocyte-colony stimulating factor (G-CSF) shows promise as a treatment for stroke. This systematic review assesses G-CSF in experimental ischaemic stroke.
Gibson, Claire L., Bath, Philip M.W., England, Timothy J.   +2 more
core   +1 more source