Results 41 to 50 of about 176,381 (301)

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Granulocyte Colony-Stimulating Factor-Producing Bladder Cancer

Case Reports in Oncology, 2019
Granulocyte colony-stimulating factor (G-CSF)-producing bladder cancer is rare, with only 75 cases reported in Japan. A 67-year-old woman was referred to our institution for the further examination of gross hematuria.
Ryota Morinaga, Takashi Kawahara, Shinnosuke Kuroda, Yoshiaki Inayama, Hiroji Uemura   +4 more
doaj   +1 more source

Induction of inhibitory central nervous system-derived and stimulatory blood-derived dendritic cells suggests a dual role for granulocyte-macrophage colony-stimulating factor in central nervous system inflammation [PDF]

, 2017
The mononuclear phagocyte system, particularly dendritic cells, plays several pivotal roles in the development of multiple sclerosis and its animal model, experimental autoimmune encephalomyelitis.
Fontana, Adriano, Heikenwalder, Mathias, Hesske, Lysann, Prinz, Marco, Reith, Walter, Suter, Tobias, Vincenzetti, Christine   +6 more
core  

GM-CSF Inhibits c-Kit and SCF Expression by Bone Marrow-Derived Dendritic Cells. [PDF]

, 2017
Stem cell factor (SCF), the ligand of c-kit, is a key cytokine for hematopoiesis. Hematopoietic precursors express c-kit, whereas differentiated cells of hematopoietic lineage are negative for this receptor, with the exception of NK cells, mast cells ...
Adachi, Alloatti, Ashman, Balan, Banchereau, Bar-On, Barnden, Bonetti, Borg, Breton, Broudy, Broz, Burgdorf, Cavanagh, Cebrian, Di Rosa, Dubois, Eash, Filippi, Gallucci, Guilliams, Haniffa, Heinrich, Helft, Hogquist, Hotchkiss, Huang, Inaba, Kassianos, Kingston, Krishnamoorthy, Lacombe, Lennartsson, Li, Liu, Liu, Lundberg, Lundberg, Lutz, Mensen, Merad, Merad, Mildner, Miller, Nagase, Nair, Oriss, Palucka, Parretta, Pastille, Politikos, Ponzetta, Quinci, Reber, Reith, Ricart, Roskoski, Russell, Saft, Sallusto, Sallusto, Sapoznikov, Sathe, Shortman, Sozzani, Sozzani, Szyska, Testa, van de Laar, von Bonin, Vremec, Wang, Waskow, Welham, Welker, Yang, Yen, Zanoni, Zelenay, Zou   +79 more
core   +2 more sources

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Granulocyte-colony stimulating factor producing rectal cancer

World Journal of Surgical Oncology, 2008
Background Granulocyte-colony stimulating factor (G-CSF)-producing cancer has been reported to occur in various organs, especially the lung. However, G-CSF-producing colorectal cancer (CRC) has never been reported in the English literature.
Satoh Mikinori, Sawai Hirozumi, Funahashi Hitoshi, Wakasugi Takehiro, Takayama Satoru, Sakamoto Masaki, Ochi Nubuo, Yasuda Akira, Takahashi Hiroki, Akamo Yoshimi, Takeyama Hiromitsu   +10 more
doaj   +1 more source

Implantation of a poly-L-lactide GCSF-functionalized scaffold in a model of chronic myocardial infarction [PDF]

, 2017
A previously developed poly-l-lactide scaffold releasing granulocyte colony-stimulating factor (PLLA/GCSF) was tested in a rabbit chronic model of myocardial infarction (MI) as a ventricular patch.
Chello, Massimo, Crescenzi, Anna, De Marco, Federico, Gambardella, Ivancarmine, Nappi, Francesco, Nenna, Antonio, Rainer, Alberto, Sedati, Pietro, Spadaccio, Cristiano, Taffon, Chiara, Trombetta, Marcella   +10 more
core   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

Costimulatory molecule-deficient dendritic cell progenitors (MHC class II⁺, CD80(dim), CD86^-) prolong cardiac allograft survival in nonimmunosuppressed recipients [PDF]

, 1996
We have shown previously that granulocyte-macrophage colony-stimulating factor-stimulated mouse bone marrow-derived MHC class II+ dendritic cell (DC) progenitors that are deficient in cell surface expression of the costimulatory molecules B7-1 (CD8O) and
Angus W. Thomson, Azuma, Boussiotis, Boussiotis, Clare-Salzler, Demetris, Frances Chambers, Freeman, Freeman, Fumin Fu, Gimmi, Go, Hathcock, Inaba, Inaba, Inaba, Jenkins, Jenkinson, John J. Fung, Khoury, Kraal, Larsen, Lin, Lina Lu, Linsley, Lu, Lu, Lu, Lu, Matzinger, Pearson, Qian, Rastellini, Reis e Sousa, Sakamoto, Sayegh, Shiguang Qian, Starzl, Starzl, Steinman, Swiggard, Talmor, Taniguchi, Thomas E. Starzl, Thomson, Turka, Van Gool, Woo, Youping Li   +48 more
core   +1 more source

Advanced 3D Platforms for Modeling CNS Neuroinflammation: Cell Integration, Techniques, and Challenges

Advanced Healthcare Materials, EarlyView.
This review summarizes the roles of key central nervous system cell types, the extracellular matrix, and the blood‐brain barrier in neuroinflammation, and their integration into diverse 3D culture systems. It examines major incorporation strategies, including direct co‐culture, hydrogel encapsulation, transwell migration assays, and bioprinting ...
Emmanuelle D. Aiyegbusi, Julia Di Stefano, Dearbhaile Dooley   +2 more
wiley   +1 more source