Results 51 to 60 of about 176,381 (301)

A Long‐Lived Human Neurovascular PENTA Culture Model Captures Incomplete Vascular Repair and Glia‐Associated Signaling After Traumatic Brain Injury

open access: yesAdvanced Healthcare Materials, EarlyView.
A long‐lived, five‐cell‐type human neurovascular (PENTA) model recreates vascular disorganization and incomplete repair after traumatic brain injury (TBI). By integrating endothelial, glial, neuronal, and immune components within a 3D scaffold, the platform enables time‐resolved analysis of neurovascular remodeling and provides a human‐relevant system ...
Daniel S. Hinrichsen   +6 more
wiley   +1 more source

Granulocyte Colony-Stimulating Factor [PDF]

open access: yes, 2020
Granulocyte colony-stimulating factor was discovered during attempts to define the normal regulators present in cell supernatants that could induce terminal differentiation of the murine myeloid leukemic cell line WEHI-3B D+. The purification and subsequent cloning of both murine and human G-CSF allowed the normal functions of this molecule to be ...
Andrew W. Roberts, Nicos A. Nicola
openaire   +2 more sources

Impact of constitutional polymorphisms in VCAM1 and CD44 on CD34+ cell collection yield after administration of granulocyte colony-stimulating factor to healthy donors

open access: yesHaematologica, 2011
Background The number of CD34+ cells mobilized from bone marrow to peripheral blood after administration of granulocyte colony-stimulating factor varies greatly among healthy donors.
Beatriz Martín-Antonio   +8 more
doaj   +1 more source

Aggressive Recurrent Pancreatic Cancer Producing Granulocyte Colony-Stimulating Factor

open access: yesCase Reports in Gastroenterology, 2020
Granulocyte colony-stimulating factor (G-CSF) is a glycoprotein which stimulates the proliferation, differentiation, and functional activation of myeloid hematopoietic cells. G-CSF-producing pancreatic cancer is rare and its prognosis is strikingly poor.
Yoshifumi Morita   +10 more
doaj   +1 more source

Granulocyte colony‐stimulating factor is not pathogenic in lupus nephritis

open access: yesImmunity, Inflammation and Disease, 2021
Systemic lupus erythematosus (lupus) is an autoimmune disease characterized by autoantibodies that form immune complexes with self‐antigens, which deposit in various tissues, leading to inflammation and disease.
Timothy A. Gottschalk   +3 more
doaj   +1 more source

Use of recombinant human granulocyte-macrophage colony stimulating factor in an infant with reticular dysgenesis [PDF]

open access: yes, 1995
We present the case of a 2-month-old infant with reticular dysgenesis who was treated with recombinant granulocyte-macrophage colony stimulating factor with the aim of stimulating granulopoiesis while awaiting bone marrow ...
Alzina, V. (Valentín)   +4 more
core  

Manufacturing Dendritic Cells for Immunotherapy: Monocyte Enrichment [PDF]

open access: yes, 2020
Dendritic cells play a key role in activation of the immune system as potent antigen-presenting cells. This pivotal position, along with the ability to generate dendritic cells from monocytes and ready uptake of antigen, makes them an intriguing vehicle ...
Cox, Cheryl, Hopewell, Emily L.
core   +1 more source

Safe and Localized Lentiviral Gene Delivery via Injectable Mesoporous Scaffolds for Potent Antitumor Immunity

open access: yesAdvanced Materials, EarlyView.
This work introduces an injectable mesoporous silica rod scaffold that confines lentiviral vectors to the injection site, enabling localized dendritic cell recruitment and transduction. The platform sustains antigen expression, promotes robust T‐cell activation, and enhances antitumor immunity.
Thanh Loc Nguyen   +12 more
wiley   +1 more source

Double‐ring sign in granulocyte colony‐stimulating factor‐induced vasculitis

open access: yesRespirology Case Reports, 2022
Key message If a double‐ring sign is found in contrast‐enhanced computed tomography, this should raise concern not only for Takayasu arteritis, but also for granulocyte colony‐stimulating factor‐induced vasculitis.
Reimi Mizushima   +5 more
doaj   +1 more source

Effects of EDTA-Induced Hypocalcaemia and Stress on Plasma TNF-α, IL-1-ra, G-CSF, GM-CSF and S-100 in Dairy Cows [PDF]

open access: yes, 2018
The pathophysiology of postparturient paresis is still not completely understood. Knowledge recently acquired in immunology, endocrinology and cell physiology has still to be integrated in order to elucidate the aetiopathogenesis of the disease. For that
Döbeli, M.   +5 more
core  

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