Results 71 to 80 of about 4,628,372 (257)

Macrophage Colony-stimulating Factor in Cooperation with Transforming Growth Factor-β1 Induces the Differentiation of CD34+ Hematopoietic Progenitor Cells Into Langerhans Cells Under Serum-free Conditions Without Granulocyte-macrophage Colony-stimulating Factor [PDF]

, 2003
Macrophage colony-stimulating factor has not been considered as a factor responsible for dendritic cell or Langerhans cell development from hematopoietic progenitor cells.
Manome, Hideaki, Setsuya Aiba, Mizuashi, Masato, Ohtani, Tomoyuki, Hara, Masahiro, Masahiro Hara, Hideaki Manome, Aiba, Setsuya, Nakagawa, Satoshi, Yoshino, Yumiko, Yumiko Yoshino, Tagami, Hachiro, Satoshi Nakagawa, Tomoyuki Ohtani, Mollah, Zia U.A., Hachiro Tagami, Masato Mizuashi, Zia U.A. Mollah   +17 more
core   +1 more source

T cells, the Next Big Target in Axial Spondyloarthritis?

Arthritis &Rheumatology, EarlyView.
Axial spondyloarthritis (axSpA) is a chronic inflammatory disease characterized by complex immune dysregulation, with T cells playing a central role in its pathogenesis. In this review, we synthesize current knowledge on diverse T cell subsets in axSpA, their pathogenic mechanisms, and emerging therapeutic strategies targeting these cells. We highlight
Mansi K. Aparnathi, Nigil Haroon
wiley   +1 more source

Granulocyte-macrophage colony-stimulating factor inhibits HIV-1 replication in monocyte-derived macrophages

, 2000
Granulocyte-macrophage colony-stimulating factor inhibits HIV-1 replication in monocyte-derived ...
H Chan (7732445), S Sonza (13719724), A Maerz (13711384), S Crowe (13428231), T Warby (13726843), K Kedzierska (9863357), A Lopez (7734548), A Jaworowski (9684227), Johnson Mak (13082904)   +8 more
core  

Clozapine-Associated Agranulocytosis Treatment With Granulocyte Colony-Stimulating Factor/Granulocyte-Macrophage Colony-Stimulating Factor [PDF]

, 2017
PURPOSE/BACKGROUND: Clozapine is associated with hematological abnormalities, notably neutropenia, which may progress to agranulocytosis. Granulocyte colony-stimulating factor (G-CSF) and granulocyte-macrophage colony-stimulating factor (GM-CSF) have ...
Eromona Whiskey, Amir Krivoy, Flanagan, Robert J., Lally, John, John Lally, David M. Taylor (4342150), Robert J. Flanagan, James H. MacCabe (7955552), Fiona P. Gaughran (7955543), MacCabe, James H.; id_orcid, Aleksandar Mijovic (7955549), Aleksandar Mijovic, Mijovic, Aleksandar, David M. Taylor, Eromona Whiskey (7955540), Malik, Steffi, Gaughran, Fiona P.; id_orcid, John Lally (7896821), James H. MacCabe, Taylor, David M.; id_orcid, Steffi Malik (7955525), Whiskey, Eromona, Amir Krivoy (6667283), Steffi Malik, Robert J. Flanagan (7955546), Krivoy, Amir, Fiona P. Gaughran   +26 more
core   +1 more source

Deep Immunophenotyping Reveals Distinct Immune Signatures in Axial Spondyloarthritis and Psoriatic Arthritis

Arthritis &Rheumatology, EarlyView.
Objective Axial spondyloarthritis (axSpA) and psoriatic arthritis (PsA) are overlapping yet distinct conditions within the SpA spectrum. As divergent immunophenotypes may influence disease course and therapeutic response, we compared immune cell subsets, cytokine profiles, and inflammatory mediators.
Natalie Frede, Nils Craig‐Müller, Silke Kohrt, Marei‐Theresa Bott, Ulrich Salzer, Ana Cecilia Venhoff, Jens Thiel, Julia Frede, Reinhard E. Voll, Marta Rizzi, Raquel Lorenzetti, Nils Venhoff   +11 more
wiley   +1 more source

Evaluation of a biosimilar granulocyte colony-stimulating factor (filgrastim XM02) for peripheral blood stem cell mobilization and transplantation: a single center experience in Japan

, 2017
Hideaki Yoshimura, Masaaki Hotta, Takahisa Nakanishi, Shinya Fujita, Aya Nakaya, Atsushi Satake, Tomoki Ito, Kazuyoshi Ishii, Shosaku Nomura First Department of Internal Medicine, Kansai Medical University, Hirakata, Osaka ...
Ito T, Hotta M, Fujita S, Ishii K, Nakanishi T, Yoshimura H, Nakaya A, Nomura S, Satake A   +8 more
core  

Efficacy and safety of empagliflozin for treating neutropenia and neutrophil dysfunction in paediatric patients with glycogen storage disease type Ib: A systematic review and meta‐analysis

British Journal of Clinical Pharmacology, EarlyView.
Aims Glycogen storage disease type Ib (GSD‐Ib) is a rare genetic disorder causing neutropenia and neutrophil dysfunction in children. G‐CSF has been the primary treatment, but emerging data support the potential of empagliflozin, an SGLT2 inhibitor, as a promising investigational option.
Elizabeth Iwasyk, Ryan Jin, Fabio Tuzzolino, Giusy Ranucci, Donatella Madonia, Alessio Provenzani   +5 more
wiley   +1 more source

Optimized micro‐sized cell sphere‐matrix niche co‐aggregates promote efficient oral and craniomaxillofacial bone regeneration

BMEMat, EarlyView.
The construct of cell‐niche co‐aggregates (GelMA‐SHED sphere‐DDMPs) promotes cranial and periodontal bone regeneration and ensures angiogenic‐osteogenic coupling by downregulating miR‐34c‐5p to enhance the expression of NOTCH1 and its intracellular domain (NICD).
Xiao‐Hui Zhang, Shi‐Han Mu, Yi‐Han Xiao, Lu‐Fan Yang, Peng‐Fei Wang, Teng‐Fei Hu, Jun‐Xi He, Jiong‐Zhen Piao, Sha Zhang, Jin‐Yu Liu, Yi‐De He, Ying‐Ying Wu, Si‐Qi Ying, Xin‐Yue Cai, Chen‐Han Li, Zi‐Qi Zhang, Xiao Lei, Ji Chen, Jian‐Fei Liang, Yan Jin, Bing‐Dong Sui, Chao Ma, Chen‐Xi Zheng, Fang Jin   +23 more
wiley   +1 more source

Overall Survival Benefit and Long‐Term Safety of Romiplostim in Persistent Chemotherapy‐Induced Thrombocytopenia

American Journal of Hematology, EarlyView.
Andrew B. Song, Gerald A. Soff
wiley   +1 more source

From pathogen to “living drug factory” innovative strategies and clinical translation of bacteria as programmable intelligent vectors for cancer therapy

BMEMat, EarlyView.
Engineered bacteria serve as smart, living therapeutics that target tumors, deliver drugs, and remodel immunosuppressive microenvironments. This review highlights their potential to potentiate immunotherapy, radiotherapy, and chemotherapy, offering a promising paradigm for precise and synergistic cancer treatment. Abstract The dynamic interplay between
Haonan Shen, Weichen Zhang, Gaoli Niu, Li Wang, Ruiyan Li, Yueyue Fan, Feixue Lu, Lingling Xu, Xiaoyuan Ji, Yong Kang   +9 more
wiley   +1 more source