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Granulocyte Colony-Stimulating Factors

2004
Granulocyte colony-stimulating factor (G-CSF) is a major regulator of the development of antibacterial neutrophilic granulocytic leukocytes (neutrophils). In keeping with the functions of both G-CSF and neutrophils, the murine molecule was first purified from medium that had bathed the dissected lungs of animals previously treated with a bacterial cell-
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Granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor in the treatment of myeloid leukemia

Current Opinion in Hematology, 1995
Hematopoietic growth factors primarily used in patients with acute myelogenous leukemia after chemotherapy could reduce significantly the neutrophil recovery time in all patients. In high-risk acute myelogenous leukemia, trials also reported a reduction in the incidence of documented infections and early mortality rate.
D, Hoelzer, G, Seipelt
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Granulocyte-Macrophage Colony-stimulating Factor

Biotherapy, 1990
Publisher Summary Granulocyte-macrophage colony-stimulating factor (GM-CSF) is one of the four classical colony-stimulating factors discovered in the 1960s following the introduction of semi-solid bone-marrow culture techniques. The human GM-CSF gene is located on chromosome 5 (q25–q31) within 10 kb of the interleukin-3 (IL-3) gene and in the same ...
S, Devereux, D C, Linch
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Granulocyte colony stimulating factor.

Methods in enzymology, 1986
Granulocyte colony-stimulating factor was discovered during attempts to define the normal regulators present in cell supernatants that could induce terminal differentiation of the murine myeloid leukemic cell line WEHI-3B D+. The purification and subsequent cloning of both murine and human G-CSF allowed the normal functions of this molecule to be ...
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Granulocyte Colony-Stimulating Factor

2020
Granulocyte colony-stimulating factor was discovered during attempts to define the normal regulators present in cell supernatants that could induce terminal differentiation of the murine myeloid leukemic cell line WEHI-3B D+. The purification and subsequent cloning of both murine and human G-CSF allowed the normal functions of this molecule to be ...
Andrew W. Roberts, Nicos A. Nicola
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Granulocyte Colony-Stimulating Factor

2017
Granulocyte colony-stimulating factor (G-CSF) is a potent hematopoietic protein that promotes the development and function of granulocytes and mobilizes stem/progenitor cells from the bone marrow. Recent studies have shown that G-CSF also directly influences the activity of some non-hematopoietic cells, such as cardiomyocytes, endothelial cells, and ...
Yasuyuki Fujita, Atsuhiko Kawamoto
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Granulocyte-Macrophage Colony-Stimulating Factor

Journal of Pediatric Oncology Nursing, 1991
D L, Betcher, N, Burnham
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