Inflammatory and Immunological Basis of Periodontal Diseases
Journal of Periodontal Research, EarlyView.The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima +3 more
wiley +1 more source
Elevation of Granulocyte Colony Stimulating Factor in Human AMD Donor RPE-Choroid. [PDF]
Invest Ophthalmol Vis SciMulfaul K +10 more
europepmc +1 more source
Macrophage Phenotype Alterations in Treated Periodontitis Patients Suggest a Pro‐Inflammatory Bias
Journal of Periodontal Research, EarlyView.Monocyte‐derived macrophages from successfully treated stage III periodontitis patients show a persistent skewing toward an M1‐like pro‐inflammatory phenotype across polarization conditions, suggesting that immune dysregulation may persist despite clinical periodontal stability.
Mariane Cristina Sloniak +5 more
wiley +1 more source
Granulocyte colony-stimulating factor promotes regeneration of severed facial nerve in rats. [PDF]
Front NeurosciFujimaki Y +4 more
europepmc +1 more source
Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases
Journal of Periodontal Research, EarlyView.This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini +3 more
wiley +1 more source
Acidic pH Restricts Non‐Tuberculous Mycobacteria Replication
Molecular Microbiology, EarlyView.Different nontuberculous mycobacteria (NTM) species display unique replication profiles in acidic pH in vitro which correlates to their replication within human macrophages. Inhibition of the acidic environments within the macrophage enhances bacterial viability emphasising the role of acidic pH during NTM infections.
Parise K. Lockwood +3 more
wiley +1 more source
Combination of 2-Chlorodeoxyadenosine, Cytarabine, and Granulocyte Colony-Stimulating Factor and Venetoclax in a Case of Acute Myelogenous Leukemia. [PDF]
J Med CasesJackert EP +5 more
europepmc +1 more source
Obesity Reviews, EarlyView.ABSTRACT In a scenario with increasing cases of obesity and diabetes worldwide, branched‐chain amino acids (BCAA) metabolism has become an important factor in the understanding of these pathologies. More recently, its chronic high plasma levels have been postulated, alongside glucose, inflammatory factors, and other molecules, as an important ...
Bernardo Starling‐Soares +4 more
wiley +1 more source
Clinical Experience With Preventing Chemotherapy-Induced Neutropenia in Breast Cancer Patients With Different Timings of Pegylated Granulocyte Colony-Stimulating Factor (PEG-G-CSF) Injection: A Case Series. [PDF]
CureusTominaga Y, Furukawa K.
europepmc +1 more source
Toll Like Receptor 4: A Potential Link Between Obesity and Metabolic Diseases
Obesity Reviews, EarlyView.ABSTRACT Epidemiological evidence shows that obesity increases the risk of developing metabolic diseases. Nevertheless, the mechanisms behind this connection remain underappreciated. The substantial impact of these disorders on global health has led to extensive research efforts aimed at identifying the pathophysiological links between them.
Ghadeer Alhamar +4 more
wiley +1 more source