Results 31 to 40 of about 78,728 (163)

Sacral Myeloid Sarcoma Manifesting as Radiculopathy in a Pediatric Patient: An Unusual Form of Myeloid Leukemia Relapse

open access: yesCase Reports in Radiology, 2018
Myeloid sarcoma (MS), granulocytic sarcoma or chloroma, is defined as a localized extramedullary mass of blasts of granulocytic lineage with or without maturation, occurring outside the bone marrow.
Joana Ruivo Rodrigues   +3 more
doaj   +1 more source

Extra medullar Granulocytic sarcoma: a case report of an exceptional localization

open access: yesJournal of Mind and Medical Sciences, 2020
Granulocytic sarcoma is a rare type of tumor composed of extramedullary immature cells. The breast location is very rare; it accounts for less than 8% of cases.
Bouhani Malek   +5 more
doaj   +1 more source

Granulocytic sarcoma: A case series and review

open access: yesJournal of Applied Hematology, 2021
Granulocytic sarcomas (GSs) are rare, solid, extramedullary tumors composed of immature myeloid cells. They can be seen before, concomitantly with or after a diagnosis of acute myeloid leukemia, chronic myeloid leukemia, or myelodysplastic syndromes.
M .P Rakesh   +3 more
doaj   +1 more source

The Cancer Cell Metabolic Reprogramming Remodels the Tumor Microenvironment: Molecular Mechanisms and Therapeutic Strategies

open access: yesAdvanced Science, EarlyView.
This review elucidates how cancer cell metabolic reprogramming—across glucose, lipid, amino acid, and nucleotide pathways—remodels the tumor microenvironment to suppress anti‐tumor immunity and promote immune escape. Targeting these metabolic axes offers promising strategies to overcome immunotherapy resistance and enhance cancer treatment.
Guoqing Xiang   +5 more
wiley   +1 more source

GRANULOCYTIC SARCOMA OF THE CNS AS A CAUSE OF MEDULLARY COMPRESSION: A CASE REPORT

open access: yesHematology, Transfusion and Cell Therapy, 2021
Case presentation: A 24-year-old man, previously healthy, presented to the hospital emergency in February 2021, complaining of pain in the back region radiating to the flanks and hips for 12 days. He had previously sought care on three occasions, without
HC Custodio   +3 more
doaj   +1 more source

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher   +7 more
wiley   +1 more source

Mediastinal nonleukemic granulocytic sarcoma with cardiac infiltration Sarcoma granulocítico mediastinal não associado à leucemia com infiltração cardíaca

open access: yesRevista Brasileira de Hematologia e Hemoterapia, 2008
We report on a case of mediastinal granulocytic sarcoma with cardiac infiltration in a young man with no evidence of leukemia involving the bone marrow or peripheral blood.
Gabrielle G. Lima   +5 more
doaj   +1 more source

Human biomarker navigator

open access: yesiMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li   +29 more
wiley   +1 more source

Granulocytic sarcoma of the breast without development of bone marrow involvement: a case report

open access: yesDiagnostic Pathology, 2009
A 29-year-old woman presented with a breast tumor with a primary diagnosis of MALT lymphoma. A repeat biopsy revealed a hematological neoplasm with diffuse, Indian file, and targetoid patterns. The cells were intermediate size with eosinophilic granules;
Quintero-Cuadra L Yolanda   +3 more
doaj   +1 more source

Peptide‐directed nanovehicles enabling tumor‐selective ROS amplification and antitumor immunity

open access: yesVIEW, EarlyView.
Cancer cells are vulnerable to oxidative stress, yet exploit immune tolerance to escape destruction. In contrast, their metabolic profile is markedly altered to support rapid proliferation, accompanied by elevated production of reactive oxygen species (ROS).
Manuela Calin   +3 more
wiley   +1 more source

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