Macrophage transactivation for chemokine production identified as a negative regulator of granulomatous inflammation using agent-based modeling [PDF]
Cellular activation in trans by interferons, cytokines and chemokines is a commonly recognized mechanism to amplify immune effector function and limit pathogen spread. However, an optimal host response also requires that collateral damage associated with
Andrews, Paul S.+8 more
core +4 more sources
Interferon regulatory factor 8-deficiency determines massive neutrophil recruitment but T cell defect in fast growing granulomas during tuberculosis [PDF]
Following Mycobacterium tuberculosis (Mtb) infection, immune cell recruitment in lungs is pivotal in establishing protective immunity through granuloma formation and neogenesis of lymphoid structures (LS).
A Dorhoi+58 more
core +7 more sources
The sarcoid granuloma: ‘epithelioid’ or ‘lymphocytic-epithelioid’ granuloma? [PDF]
Background: This study aims to analyze the structure and quantities of cellular elements in sarcoid granulomas. Methods: We investigated 34 transbronchial lung biopsy samples obtained from 34 sarcoid patients. The quantity and composition of the cellular elements inside a granuloma were determined by the quantitative stereometry method, employing the ...
Bojan Zaric+5 more
openaire +5 more sources
Generalized granuloma annulare after pneumococcal vaccination, [PDF]
Granuloma annulare may be caused by multiple triggers. Among these are vaccinations, which have been described as an infrequent cause of granuloma annulare.
Miguel Fernando García-Gil+3 more
doaj +1 more source
Usefulness of image guidance in the surgical treatment of petrous apex cholesterol granuloma [PDF]
The petrous apex is a pyramid-shaped structure, located medial to the inner ear and the intrapetrous segment of the internal carotid artery. Lesions of the petrous apex can be surgically treated through different surgical routes. Because of the important
A. Pietrantonio+5 more
core +3 more sources
Pyogenic granuloma of the incisive papilla: A rare case report
Pyogenic granuloma is a non-neoplastic reactive growth commonly found in the oral cavity and skin. It is benign in origin and may arise due to factors like trauma, local minor irritation and an imbalance in the levels of hormones. Oral pyogenic granuloma
Devika S Pıllaı+5 more
doaj +1 more source
Naming and recognition of six foot lesions of sheep using written and pictorial information: a study of 809 English sheep farmers [PDF]
In 2005, 3000 questionnaires were sent to a random sample of English sheep farmers from a list kept by the English Beef and Lamb Executive (EBLEX) to investigate whether farmers could correctly name six common foot lesions in sheep from a characteristic ...
Green, Laura E., Kaler, Jasmeet
core +2 more sources
Are CD68 and Factor VIII-RA Expression Different in Central and Peripheral Giant Cell Granuloma of Jaw: An Immunohistochemical Comparative Study [PDF]
Objective: Central giant cell granuloma and peripheral giant cell granuloma of the jaw and oral cavity are identical in histopathologic features, although they are different in pathogenesis and clinical behavior.
Soudabeh SARGOLZAEİ+2 more
doaj +1 more source
Effects of Mitomycin C in Early Conjunctival Inflammation after Pterygium Surgery [PDF]
Purpose: The purpose of this study was to compare inflammatory events and graft characteristics 1 month and 6 months after conjunctival limbal autograft (CLAU) with and without intraoperative mitomycin C (MMC).
Asaad Ammaar, Mouafk+4 more
core +2 more sources
Differences in reactivation of tuberculosis induced from anti-tnf treatments are based on bioavailability in granulomatous tissue [PDF]
The immune response to Mycobacterium tuberculosis (Mtb) infection is complex. Experimental evidence has revealed that tumor necrosis factor (TNF) plays a major role in host defense against Mtb in both active and latent phases of infection.
Denise E Kirschner+7 more
core +3 more sources