Results 41 to 50 of about 92,038 (266)

Improvement of generalized granuloma annulare with adalimumab: A case report

SAGE Open Medical Case Reports
Granuloma annulare is a benign, inflammatory condition of unknown etiology, characterized by erythematous annular plaques, frequently on distal extremities.
Yara Al Horoub, Kirsten Walker
doaj   +1 more source

Atypical Clinical Course of Griscelli Syndrome Type 2 With Primarily Neurologic Presentation and Adult‐Onset in a 46‐Year‐Old Male

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Griscelli Syndrome Type 2 (GS2) is a rare autosomal recessive disorder caused by pathogenic mutations in the RAB27A gene. Typically, it is characterized by cutaneous hypopigmentation, immunodeficiency, with or without neurological abnormalities secondary to hemophagocytic lymphohistiocytosis (HLH). Without treatment, GS2 often results in fatal
Dzhoy Papingi, Michael Kutsche, Helena Lichtenfeld, Fanny Kortüm, Angela Abicht, Laura Herrmann, Theresia Herget   +6 more
wiley   +1 more source

Pregnancy tumor and facial port-wine stain: A case report

Journal of Craniomaxillofacial Research, 2018
Pyogenic granuloma is a common tumor-like growth of the oral cavity that traditionally has been considered to be non-neoplastic in nature. The pyogenic granuloma is a smooth or lobulated mass that is usually pedunculated, although some lesions are ...
Mohsen Barzegar, Adele Pouyafard, Seyed Hosein Tabatabaei, Alireza Navabazam, Hamidreza Ajami, Mehdi Chohedri   +5 more
doaj  

Granuloma annulare and possible relation to purified protein derivative administration: a case report

Journal of Medical Case Reports
Background Granuloma annulare is a noninfectious inflammatory granulomatous skin disease characterized by an erythematous or skin colored annulare plaque. The diagnosis of granuloma annulare may be challenging owing to its diverse morphology.
Ernest C. Lee, Cheryl A. Steffen, Minnerva E. Carroz, Christine L. Lee, Lysette A. Lee   +4 more
doaj   +1 more source

VEGF-A from Granuloma Macrophages Regulates Granulomatous Inflammation by a Non-angiogenic Pathway during Mycobacterial Infection

Cell Reports, 2019
Summary: Many autoimmune and infectious diseases are characterized by the formation of granulomas which are inflammatory lesions that consist of spatially organized immune cells.
Jeffrey S. Harding, Melinda Herbath, Yuli Chen, Aditya Rayasam, Anna Ritter, Balazs Csoka, George Hasko, Iacovos P. Michael, Zsuzsanna Fabry, Andras Nagy, Matyas Sandor   +10 more
doaj   +1 more source

Establishment of a chronic aspiration pneumonia mouse model using oropharyngeal aspiration of food suspension

Animal Models and Experimental Medicine, EarlyView.
Four aspiration methods (UV, IN, IT, and OA) were compared, and OA was identified as the most effective delivery technique. A chronic aspiration pneumonia model was then established through repeated OA of food suspension or gastric contents. Integrated analyses, including micro‐CT, histopathology, cytokine profiling, and RNA sequencing, revealed ...
Qianwen Li, Fansen Lin, Hongzhi Gao, Yun Zhao, Yuqi Liu   +4 more
wiley   +1 more source

Lethal Midline Granuloma

Indian Journal of Dermatology, 1995
Midline granuloma is a term with several synonyms: Stewart’s granuloma, granuloma gangraenescens nasi, lethal granuloma, polymorphous reticulosis 2-4 The conditiin is characterized by localized inflammation, destruction and often ...
Ghosh S.N, Dey S.K, Chatterjee C
doaj  

Engraftment of sheep splenic lymphocytes into NBSGW mice and application in Brucella infection

Animal Models and Experimental Medicine, EarlyView.
A sheep splenocyte‐reconstituted mouse model (Sh‐Spl mice) was established via intravenous injection of sheep splenic lymphocytes into immunodeficient mice to evaluate Brucella infection. Abstract Background The development of immune reconstituted xenograft mouse models has addressed the limitations imposed by interspecies immunological differences in ...
Xiaowei Wang, Shicheng Wan, Yanmin Guo, Hongyu Han, Fei Luo, Dongmei Jiang, Xiaorong Yang, Quanhai Pang, Haisheng Yu, Jinlian Hua   +9 more
wiley   +1 more source

Spatial Cell Death and Oxidative Stress Dynamics in Gas Plasma‐Treated Tumor Tissues

Advanced NanoBiomed Research, EarlyView.
Schematic representation of the four experimental models to study tissue penetration and oxidation. Four tissue models were used. Human pancreatic cancer cells were grown on the chorioallantois membrane of chicken embryos and gas plasma‐treated in ovo, murine colorectal tumor tissue was gas plasma‐exposed ex vivo, murine squamous cell carcinoma cells ...
Anke Schmidt, Shahrzad Rokhsary, Linus Hübner, Lea Miebach, Sander Bekeschus   +4 more
wiley   +1 more source

Case report: Generalized granuloma annulare successfully treated with baricitinib in two cases

Journal of Cutaneous Immunology and Allergy
Treatments are challenging in generalized granuloma annulare. We reported two cases of generalized granuloma annulare without diabetes mellitus; one exhibited non-annular papules and the other did patch/annular lesions.
Marina Yunoki, Shumpei Kondo, Masaki Otsuka, Yoshiki Tokura, Yoshiki Tokura   +4 more
doaj   +1 more source