Deciphering a Sleeping Pathogen: Uncovering Novel Transcriptional Regulators of Hypoxia-Induced Dormancy in Mycobacterium Tuberculosis [PDF]
Along the pathogenesis of Mycobacterium Tuberculosis (MTB), hypoxia-induced dormancy is a process involving the oxygen-depleted environment encountered inside the lung granuloma, where bacilli enter a viable, non-replicating state termed as latency. Affecting nearly two billion people, latent TB can linger in the host for indefinite periods of time ...
arxiv
Endoscopic endonasal management of recurrent petrous apex cholesterol granuloma. [PDF]
Petrous apex cholesterol granulomas (PACG) are uncommon lesions. Recurrence following transcranial or endonasal approaches to aerate the cyst occurs in up to 60% of cases. We describe the technical nuances pertinent to the endonasal endoscopic management
Carrau, Ricardo L+5 more
core +1 more source
Eosinophilic ulcer of the tongue - Case report. [PDF]
Eosinophilic ulcer of the oral mucosa is a rare, self-limiting, chronic and benign lesion of unknown pathogenesis that affects the oral mucosa. We present the case of a 65 year-old Caucasian female with a fivemonth history of a painful ulcer on the ...
Calvieri, Stefano+4 more
core +2 more sources
TREATMENT EXPERIENCE OF PATIENTS WITH LARYNGEAL GRANULOMA USING HIGH-ENERGY SURGICAL EQUIPMENT ENT
Contact vocal process granuloma causative factors are gastroesophageal reflux, intubation trauma, and vocal abuse and psychosomatics. Treatment includes proton pump inhibitors, voice therapy, psychotherapy and surgical excision in case of ...
V. M. Svistushkin+2 more
doaj +1 more source
Texture features based microscopic image classification of liver cellular granuloma using artificial neural networks [PDF]
Automated classification of Schistosoma mansoni granulomatous microscopic images of mice liver using Artificial Intelligence (AI) technologies is a key issue for accurate diagnosis and treatment.
Chen, Gaoxiang+6 more
core +1 more source
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
Hepatology, EarlyView.
Robert J. Fontana+6 more
wiley +1 more source
68Ga‐nitroimidazole PET/CT imaging of hypoxia in tuberculosis: A case series
There is increasing application of PET/CT imaging in infectious diseases such as tuberculosis. Imaging potential stressors such as hypoxia, using a novel Ga‐68 labelled hypoxia seeking agent, has the potential to identify patients who may benefit from individualised treatment strategies.
Philippa L Bresser+3 more
wiley +1 more source
Photodynamic Therapy for Granuloma Annulare: More than a Shot in the Dark [PDF]
Granuloma annulare (GA) is a benign granulomatous and inflammatory skin disorder. The pathogenesis remains enigmatic and convincingly effective treatment options are not available.
Berking, Carola+5 more
core +1 more source
Infections with pathogenic mycobacteria are controlled by the formation of a unique structure known as a granuloma. The granuloma represents a host–pathogen interface where bacteria are killed and confined by the host response, but also where bacteria ...
Dominic O. Co+5 more
doaj +1 more source
DNA repair systems and the pathogenesis of Mycobacterium tuberculosis: varying activities at different stages of infection [PDF]
Mycobacteria, including most of all MTB (Mycobacterium tuberculosis), cause pathogenic infections in humans and, during the infectious process, are exposed to a range of environmental insults, including the host's immune response.
Adams+117 more
core +1 more source