Results 21 to 30 of about 30,079 (265)

Eosinophilic granulomatosis with polyangiitis – Advances in pathogenesis, diagnosis, and treatment

Frontiers in Medicine, 2023
Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare disease characterized by eosinophil-rich granulomatous inflammation and necrotizing vasculitis, pre-dominantly affecting small-to-medium-sized vessels.
J. Fijołek, E. Radzikowska
semanticscholar   +1 more source

Clinical Characteristics of an Internet-Based Cohort of Patient-Reported Diagnosis of Granulomatosis With Polyangiitis and Microscopic Polyangiitis: Observational Study

Journal of Medical Internet Research, 2020
BackgroundUtilizing the traditional centers of excellence approach to conduct clinical trials involving rare diseases remains challenging.
Springer, Jason Michael, Kermani, Tanaz A, Sreih, Antoine, Shaw, Dianne G, Young, Kalen, Burroughs, Cristina M, Merkel, Peter A   +6 more
doaj   +1 more source

Eosinophilic granulomatosis with polyangiitis: A review.

Autoimmunity Reviews, 2022
Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare, multi-system, inflammatory disease, belonging to the group of anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAV).
White Jpe, S. Dubey
semanticscholar   +1 more source

Penile granulomatosis with polyangiitis [PDF]

JAAD Case Reports, 2019
Granulomatosis with polyangiitis (GPA) is a systemic form of vasculitis that predominantly affects small and medium-sized vessels. The organs often involved are the kidneys and respiratory tract. Diagnosis can be established based on the histologic findings of necrotizing granulomatous inflammation and vasculitis and positive test results for anti ...
Amico, Séverine, Ballan, Guillaume, Charles, Sophie, Marce, Stéphane, Devaux, Suzanne   +4 more
openaire   +2 more sources

Unmet needs and evidence gaps in hypereosinophilic syndrome and eosinophilic granulomatosis with polyangiitis.

Journal of Allergy and Clinical Immunology, 2023
Hypereosinophilic syndrome (HES) and eosinophilic granulomatosis with polyangiitis (EGPA) are rare systemic inflammatory disorders with overlapping symptoms, elevated eosinophil counts, and heterogenous clinical presentations.
M. Wechsler, B. Hellmich, M. Cid, D. Jayne, X. Tian, L. Baylis, F. Roufosse   +6 more
semanticscholar   +1 more source

Eosinophilic granulomatosis with polyangiitis developed after dupilumab administration in patients with eosinophilic chronic rhinosinusitis and asthma: a case report

BMC Pulmonary Medicine, 2023
Background Eosinophilic granulomatosis with polyangiitis (EGPA) is a form of anti-neutrophil cytoplasmic antibody (ANCA) associated vasculitis characterized by eosinophil-rich granulomatous inflammation and small-to-medium vessel vasculitis associated ...
I. Suzaki, A. Tanaka, R. Yanai, Yuki Maruyama, S. Kamimura, K. Hirano, Hitome Kobayashi   +6 more
semanticscholar   +1 more source

Clinical Benefit of Mepolizumab in Eosinophilic Granulomatosis With Polyangiitis for Patients With and Without a Vasculitic Phenotype

ACR Open Rheumatology, 2023
To evaluate mepolizumab's efficacy in eosinophilic granulomatosis with polyangiitis (EGPA) with and without a vasculitic phenotype.
B. Terrier, D. Jayne, B. Hellmich, J. Bentley, J. Steinfeld, S. Yancey, N. Kwon, P. Akuthota, P. Khoury, L. Baylis, M. Wechsler   +10 more
semanticscholar   +1 more source

Oral granulomatosis with polyangiitis a systematic review

Clinical and Experimental Dental Research, 2023
Granulomatosis with polyangiitis is an unusual multisystemic inflammatory disease, with vasculitis of small‐ and medium‐sized vessels, with a predilection for upper lower airways and kidneys.
A. Labrador, Luciano H M Valdez, N. R. G. Marín, K. R. Ibazetta, J. L. Chacon, A. J. Fernandez, M. V. Valencia, Schillin W Marchant, K. Sanchez, Cesar A Villacrez   +9 more
semanticscholar   +1 more source

Score to assess the probability of relapse in granulomatosis with polyangiitis and microscopic polyangiitis

RMD Open, 2023
Objective To develop a score assessing the probability of relapse in granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA). Methods Long-term follow-up data from GPA and MPA patients included in five consecutive randomised controlled ...
M. Samson, H. Devilliers, S. Thietart, P. Charles, C. Pagnoux, P. Cohen, A. Karras, L. Mouthon, B. Terrier, X. Puéchal, L. Guillevin   +10 more
semanticscholar   +1 more source

Response to Treatment With Tofacitinib in 11 Patients With Refractory Granulomatosis With Polyangiitis

Journal of Rheumatology, 2023
Granulomatosis with polyangiitis (GPA) is an antineutrophil cytoplasmic antibody-associated vasculitis that affects mainly small-sized vessels and is characterized by upper and lower respiratory tract, kidney, eye, skin, and neurologic involvement.
L. Linde, M. Faurschou, S. Krintel, B. Baslund   +3 more
semanticscholar   +1 more source