Results 31 to 40 of about 30,079 (265)
Eosinophilic Granulomatosis With Polyangiitis: Dissecting the Pathophysiology
Eosinophilic Granulomatosis with Polyangiitis (EGPA) is a rare multisystemic disease classified both amongst hypereosinophilic disorders and ANCA-associated vasculitis.
F. Fagni, F. Bello, G. Emmi
semanticscholar +1 more source
Mepolizumab proved to be an efficacious treatment for eosinophilic granulomatosis with polyangiitis (EGPA) at a dose of 300 mg every 4 weeks in the randomized, controlled MIRRA trial.
A. Bettiol +54 more
semanticscholar +1 more source
Clinical periodontal diagnosis
Abstract Periodontal diseases include pathological conditions elicited by the presence of bacterial biofilms leading to a host response. In the diagnostic process, clinical signs such as bleeding on probing, development of periodontal pockets and gingival recessions, furcation involvement and presence of radiographic bone loss should be assessed prior ...
Giovanni E. Salvi +5 more
wiley +1 more source
Eosinophil ETosis–Mediated Release of Galectin‐10 in Eosinophilic Granulomatosis With Polyangiitis
Eosinophils are tissue‐dwelling immune cells. Accumulating evidence indicates that a type of cell death termed ETosis is an important cell fate involved in the pathophysiology of inflammatory diseases.
M. Fukuchi +12 more
semanticscholar +1 more source
The role of the host—Neutrophil biology
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
wiley +1 more source
Cocaine-induced granulomatosis with polyangiitis—an under-recognized condition
Objectives Cocaine and cocaine mixed with levamisole are increasingly used in the UK and result in significant direct nasal damage in addition to promoting vasculitis.
C. Gill +11 more
semanticscholar +1 more source
Rituximab vs Cyclophosphamide Induction Therapy for Patients With Granulomatosis With Polyangiitis
Key Points Question Is rituximab more effective than cyclophosphamide for treatment of granulomatosis with polyangiitis (GPA)? Findings In this comparativeness effectiveness study based on clinical data from 194 patients with GPA, rituximab as induction ...
X. Puéchal +19 more
semanticscholar +1 more source
Granulomatosis with Polyangiitis (Wegener's): An alternative name for Wegener's Granulomatosis [PDF]
The Boards of Directors of the American College of Rheumatology, the American Society of Nephrology, and the European League Against Rheumatism recommend a gradual shift from honorific eponyms to disease-descriptive or etiology-based nomenclature.
Falk, R. J. +12 more
openaire +9 more sources
Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare disease associated with vascular inflammation and multisystem organ damage. The literature reporting EGPA incidence or prevalence is limited.
R. Jakes +6 more
semanticscholar +1 more source
Tension Pneumothorax as Initial Manifestation of Granulomatosis with Polyangiitis (GPA)
Granulomatosis with polyangiitis (Wegener’s granulomatosis) is a systemic vasculitis that primarily affects small and medium vessels. Its manifestations are usually confined to the upper airway, lower airway and kidney.
Rúben Reis +5 more
doaj +1 more source

