Results 91 to 100 of about 90,931 (299)
Mice previously infected with Schistosoma mansoni, and cured by specific treatment (400mg/kg oxamniquine, p. o.) in the chronic phase of the disease, were reinfected 20 days after treatment to assess their capacityfor modulation ofthe granulomatous ...
Paulo Marcos Z. Coelho +3 more
doaj +1 more source
A Zebrafish Model of Mycobacterium leprae Granulomatous Infection. [PDF]
Understanding the pathogenesis of leprosy granulomas has been hindered by a paucity of tractable experimental animal models. Mycobacterium leprae, which causes leprosy, grows optimally at approximately 30°C, so we sought to model granulomatous disease in
Cameron, James +2 more
core +2 more sources
Chronic granulomatous disease is an inherited defect in intracellular killing of ingested microorganisms characterized by recurrent life threatening bacterial and fungal infections including invasive aspergillosis in early childhood.
Ilad Alavi Darazam +5 more
doaj
Chronic granulomatous disease (CGD) is a heterogeneous condition due to defects in NADPH oxidase characterized by granuloma formation and increased susceptibility to invasive infections, in particular moulds.
Ahmed Babiker +9 more
doaj +1 more source
Spontaneous melanotic lesions in axillary seabream, Pagellus acarne (Risso) [PDF]
In this paper, we describe spontaneous melanotic lesions in the skin of axillary seabream, Pagellus acarne (Risso) from a defined area of the Portuguese Coast, located in Cabo da Roca and Foz do Arelho.
Branco, Sandra, Ramos, Paula, Victor, P
core +1 more source
Papulopustular Dermatitis in X-Linked Chronic Granulomatous Disease
Here we describe two term male infants diagnosed with X-linked CGD who present, in addition to frequent infection, with a unique papulopustular skin rash. CGD is caused by a number of genetic defects that impair phagocyte function.
Puja Sood Rajani, Maria A. Slack
doaj +1 more source
Actinomycosis may be presented in unusual organs: A report of two cases [PDF]
Actinomycosis is a chronic granulomatous suppurative disease characterized by direct extension to the contagious tissue with the formation of multiple drainage sinus tracts through which tiny colonies of organisms called sulfur granules are discharged ...
Golsha, R. +5 more
core
Gammaretrovirus-mediated correction of SCID-X1 is associated with skewed vector integration site distribution in vivo [PDF]
We treated 10 children with X-linked SCID (SCID-X1) using gammaretrovirus-mediated gene transfer. Those with sufficient follow-up were found to have recovered substantial immunity in the absence of any serious adverse events up to 5 years after treatment.
Kerstin Schwarzwaelder +53 more
core +2 more sources
This study employed multi‐omics approaches to investigate the regulatory mechanism of Mycobacterium PknG on host cell processes. We found that host lysine‐tRNA ligase (KARS) is a potential substrate of PknG; and PknG can regulate the immune response by catalyzing the phosphorylation of KARS at T592 and T595 sites, affecting the phosphorylation level in
Nana Tian +13 more
wiley +1 more source

