Results 101 to 110 of about 1,240,530 (301)

Schistosoma mansoni in mice: modulation of granulomatous response after reinfection and chemotherapeutic treatment

Revista da Sociedade Brasileira de Medicina Tropical, 1994
Mice previously infected with Schistosoma mansoni, and cured by specific treatment (400mg/kg oxamniquine, p. o.) in the chronic phase of the disease, were reinfected 20 days after treatment to assess their capacityfor modulation ofthe granulomatous ...
Paulo Marcos Z. Coelho, Pedro Raso, Rômulo Teixeira de Mello, Nivaldo H. Toppa   +3 more
doaj   +1 more source

Elevated MicroRNA-33 in Sarcoidosis and a Carbon Nanotube Model of Chronic Granulomatous Disease.

American Journal of Respiratory Cell and Molecular Biology, 2016
We established a murine model of multiwall carbon nanotube (MWCNT)-induced chronic granulomatous disease, which resembles human sarcoidosis pathology. At 60 days after oropharyngeal MWCNT instillation, bronchoalveolar lavage (BAL) cells from wild-type ...
B. Barna, M. McPeek, A. Malur, M. Fessler, C. Wingard, L. Dobbs, K. Verbanac, M. Bowling, M. Judson, M. Thomassen   +9 more
semanticscholar   +1 more source

Endomyocardial biopsy in the diagnosis of cardiac sarcoidosis

European Journal of Heart Failure, EarlyView.
The diagnostic performance of endomyocardial biopsy (EMB) in 216 patients with cardiac sarcoidosis (CS). The overall sensitivity of the first EMB was 38%, although it varied markedly depending on the extent and severity of the disease. Major complications were rare (<1%) and no deaths or permanent sequels were observed.
Henriikka Mälkönen, Jukka Lehtonen, Pauli Pöyhönen, Valtteri Uusitalo, Mikko I. Mäyränpää, Markku Kupari   +5 more
wiley   +1 more source

Granulomatosis with polyangiitis: Common and uncommon presentations

Journal of Medical Imaging and Radiation Oncology, Volume 66, Issue 8, Page 1089-1096, December 2022., 2022
Summary Granulomatosis with polyangiitis (GPA) is a multisystemic autoimmune small vessel vasculitis predominantly affecting the respiratory and renal systems. Other systems such as the central nervous system, orbital, cardiac and gastrointestinal systems may also be involved to a lesser degree.
Qiao Xin Tee, Aaron Wong, Mithun Nambiar, Kenneth K Lau   +3 more
wiley   +1 more source

Common severe infections in chronic granulomatous disease.

Clinical Infectious Diseases, 2015
BACKGROUND Chronic granulomatous disease (CGD) is due to defective nicotinamide adenine dinucleotide phosphate oxidase activity and characterized by recurrent infections with a limited spectrum of bacteria and fungi as well as inflammatory complications.
Beatriz E. Marciano, C. Spalding, A. Fitzgerald, Daphne Mann, T. Brown, S. Osgood, Lynne Yockey, D. Darnell, L. Barnhart, Janine R. Daub, L. Boris, Amy Rump, V. Anderson, C. Haney, D. Kuhns, S. Rosenzweig, Corin Kelly, A. Zelazny, T. Mason, S. DeRavin, E. Kang, J. Gallin, H. Malech, K. Olivier, G. Uzel, A. Freeman, T. Heller, C. Zerbe, S. Holland   +28 more
semanticscholar   +1 more source

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons, Marc A. Beal, Kerry L. Dearfield, George R. Douglas, Min Gi, B. Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Michelle Kenyon, Alexandra S. Long, David P. Lovell, Anthony M. Lynch, Meagan B. Myers, Stefan Pfuhler, Alisa Vespa, Andreas Zeller, George E. Johnson, Paul A. White   +17 more
wiley   +1 more source

Chinese expert consensus on the multidisciplinary management of pneumonitis associated with immune checkpoint inhibitor

Thoracic Cancer, Volume 13, Issue 23, Page 3420-3430, December 2022., 2022
Chinese expert consensus on the multidisciplinary management of pneumonitis associated with immune checkpoint inhibitor. Abstract Immune checkpoint inhibitors (ICIs) have successfully treated a number of different types of cancer, which is of great significance for cancer treatment.
Wenxian Wang, Qian Wang, Chunwei Xu, Ziming Li, Zhengbo Song, Yongchang Zhang, Xiuyu Cai, Shirong Zhang, Bin Lian, Wen Li, Anwen Liu, Ping Zhan, Hongbing Liu, Tangfeng Lv, Liyun Miao, Lingfeng Min, Yu Chen, Jingping Yuan, Feng Wang, Zhansheng Jiang, Gen Lin, Xingxiang Pu, Chuangzhou Rao, Dongqing Lv, Zongyang Yu, Xiaoyan Li, Chuanhao Tang, Chengzhi Zhou, Congying Xie, Junping Zhang, Hui Guo, Qian Chu, Rui Meng, Jingxun Wu, Rui Zhang, Liping Wang, Youcai Zhu, Xiao Hu, Yanru Xie, Xinqing Lin, Jing Cai, Fen Lan, Huijing Feng, Lin Wang, Wang Yao, Xuefei Shi, Jianhui Huang, Huafei Chen, Yinbin Zhang, Pingli Sun, Bing Wan, Fei Pang, Zanmei Xu, Kai Wang, Yuanli Xia, Mingxiang Ye, Dong Wang, Qing Wei, Shuitu Feng, Jianya Zhou, Jiexia Zhang, Donglai Lv, Wenbin Gao, Jing Kang, Genhua Yu, Xianbin Liang, Chengtao Yu, Lin Shi, Nong Yang, Lin Wu, Zhuan Hong, Wei Hong, Meiyu Fang, Yiping Zhang, Yuanzhi Lu, Guansong Wang, Shenglin Ma, Lu Si, Wenfeng Fang, Yong Song   +79 more
wiley   +1 more source

Nondiagnostic, radial‐probe endobronchial ultrasound‐guided biopsy for peripheral lung lesions: The added value of radiomics from ultrasound imaging for predicting malignancy

Thoracic Cancer, Volume 14, Issue 2, Page 177-185, January 2023., 2023
This study investigated whether radiomic features extracted from radial‐probe endobronchial ultrasound (radial EBUS) images can assist in decision‐making for subsequent clinical management in cases with indeterminate pathologic results. We demonstrated a radiomics‐added, malignancy prediction model that can categorize lesions with nondiagnostic lung ...
Jihwan Choi, Sungmin Zo, Jong Hoon Kim, You Jin Oh, Joong Hyun Ahn, Myoungkyoung Kim, Kyungjong Lee, Ho Yun Lee   +7 more
wiley   +1 more source

Calculation of the mean duration and age of onset of a chronic disease and application to dementia in Germany [PDF]

arXiv, 2011
This paper descibes a new method of calculating the mean duration and mean age of onset of a chronic disease from incidence and mortality rates. It is based on an ordinary differential equation resulting from a simple compartment model. Applicability of the method is demonstrated in data about dementia in Germany.
arxiv  

Chronic Granulomatous Disease: Report on a National Registry of 368 Patients

Medicine, 2000
A registry of United States residents with chronic granulomatous disease (CGD) was established in 1993 in order to estimate the minimum incidence of this uncommon primary immunodeficiency disease and characterize its epidemiologic and clinical features ...
J. Winkelstein, M. Marino, R. Johnston, J. Boyle, J. Curnutte, J. Gallin, H. Malech, S. Holland, H. Ochs, P. Quie, R. Buckley, C. Foster, S. Chanock, H. Dickler   +13 more
semanticscholar   +1 more source