Results 211 to 220 of about 64,916 (281)

De novo or Salvage? Nucleotide Availability as a Driver of Bacterial Adaptation and Virulence

open access: yesMicrobiologyOpen, Volume 15, Issue 4, August 2026.
Bacterial pathogens survive in different host environments by switching between making nucleotides by de novo synthesis and scavenging them from the host. This flexibility supports growth and virulence making nucleotide metabolism an attractive therapeutic target.
Riya Joshi   +2 more
wiley   +1 more source

Metabolic Regulation of Macrophages in Health and Disease

open access: yesMedComm, Volume 7, Issue 8, August 2026.
Extracellular metabolites drive metabolic rewiring of glucose, lipid, and amino acid pathways in macrophages, steering their polarization toward pro‐ or anti‐inflammatory phenotypes and shaping a wide range of disease processes. Macrophages from different tissues display distinct metabolic signatures, and therapeutic strategies that target these ...
Shan Huang   +6 more
wiley   +1 more source

Revisiting Controversial Areas in the Management of Premature Ejaculation

open access: yesTrends in Urology &Men's Health, Volume 17, Issue 4, August 2026.
ABSTRACT The cause of premature ejaculation (PE) is often multifactorial in nature, and effective management of PE is complex and should involve multimodal approaches. This narrative review examines the ongoing controversies surrounding key areas in the diagnosis and treatment of PE with an emphasis on future research directions to align clinical care ...
Dong Sup Lee   +6 more
wiley   +1 more source

Chronic Granulomatous Disease of the Upper Airway

open access: yesEar, Nose & Throat Journal
Brad Bradshaw MS   +7 more
doaj   +1 more source

Gingival enlargement and dentition loss associated with disseminated Cryptococcus neoformans infection in a dog

open access: yesVeterinary Record Case Reports, Volume 14, Issue 3, August 2026.
Abstract A 1‐year‐old, female, spayed, mixed‐breed dog was examined by a referring veterinarian for a 1‐week history of sneezing, bilateral mucoid nasal discharge, mild bilateral ocular discharge and stertor. During rhinoscopy, a plant awn foreign body was removed, but upper respiratory signs persisted. Computed tomography of the head revealed findings
Glynn Woods   +4 more
wiley   +1 more source

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