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Chronic granulomatous disease of childhood

Journal of Pediatric Surgery, 1969
Abstract Chronic granulomatous disease in children is a disease of recurrent sepsis in children which results from a deficiency of a white cell DPNH oxidase. The fatality of the disease has previously been emphasized. However, a spectrum of disease exists with long-term survival possible.
A I, Philippart   +2 more
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Postencephalitic Chronic Granulomatous Disease

Pediatric Neurology, 2006
This report details the evolution of a case of herpes simplex encephalitis to chronic granuloma in a 13-year old female who, at the age of 8, suffered herpes simplex virus type 1 encephalitis. Eight months later, she developed an intracranial hypertension syndrome with the onset of a new lesion in the necrosed zone of her right temporal lobe, with no ...
J M Prats, Viñas   +4 more
openaire   +2 more sources

Chronic Granulomatous Disease in an Adult

Southern Medical Journal, 1987
We have described a 49-year-old man with chronic granulomatous disease. The diagnosis was established by a deficiency of NBT dye reduction by neutrophils, in addition to impairment in 14C-1-glucose utilization, 125I-iodination of zymosan, chemiluminescence, superoxide radical generation, and bactericidal activity toward S aureus.
L S, Nerurkar   +5 more
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The management of chronic granulomatous disease

European Journal of Pediatrics, 1993
Chronic granulomatous disease (CGD) is a primary immunodeficiency disease which results from absence of the NADPH oxidase in the professional phagocytic cells neutrophils, monocytes, macrophages and eosinophils. Deficiency of this oxidase renders the patient liable to infection by bacteria and fungi, and, as the name of the disease suggests, to chronic
A, Fischer   +3 more
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Chronic granulomatous disease in adults

The Lancet, 1996
Chronic granulomatous disease (CGD), an inherited disorder of granulocyte function caused by failure of intracellular superoxide production, normally presents in the first years of life with severe recurrent bacterial and fungal infections.From the files of two children's hospitals we identified 11 CGD patients who were remarkable for an unusually late
J G, Liese   +6 more
openaire   +2 more sources

AMANTADINE IN CHRONIC GRANULOMATOUS DISEASE

Pediatric Hematology and Oncology, 2005
Chronic granulomatous disease (CGD) is a rare genetically determined immunodeficiency. Neutrophils from CGD patients show a defective killing of phagocytosed fungi and bacteria, due not only to an impairment in oxidative burst, but also to absence of normal pH value within phagocytic vacuole following phagocytosis.
GRANZOTTO M   +7 more
openaire   +2 more sources

Prostatitis in chronic granulomatous disease

The American Journal of Medicine, 1989
On rapporte le premier cas d'abces de la prostate (Ps.
T L, Zach, P G, Quie
openaire   +2 more sources

Classification of Chronic Granulomatous Disease

Hematology/Oncology Clinics of North America, 1988
Chronic granulomatous disease is a heterogeneous disorder caused by at least three, and possibly four, types of mutations. Based on recent biochemical and molecular genetic data on this disease, a classification scheme and summary of the various forms of the disease are presented.
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Chronic Granulomatous Disease 1974

JAMA: The Journal of the American Medical Association, 1975
THE office diagnosis of many newly discovered diseases caused by neutrophil dysfunction is now possible with the use of clinical criteria and relatively simple laboratory tests. Through techniques evolved in the course of elucidating rare inborn disorders, it is now feasible to approach commonplace impairments of neutrophil function which occur as ...
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Chronic granulomatous disease

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1994
A J, Thrasher   +3 more
openaire   +2 more sources

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