Results 61 to 70 of about 6,263,315 (249)

Case Reports A case of chronic granulomatous disease

, 2014
(Key words: Chronic granulomatous disease; phagocyte ...
S Sriranganathan, G N Lucas, S Gunawardene, N R De Silva   +3 more
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Pulmonary Aspergillosis in a Previously Healthy 13-Year-Old Boy

Canadian Respiratory Journal, 2016
Chronic granulomatous disease (CGD) is a rare, polygenic primary immunodeficiency. In this case report, we describe a previously healthy 13-year-old boy who presented with multifocal pulmonary aspergillosis and was subsequently diagnosed with an ...
Jonathan H. Rayment, Indra Narang
doaj   +1 more source

Therapeutic Challenges in Managing Coexisting Hidradenitis Suppurativa and Squamous Cell Carcinoma: A Clinical Case Study

JEADV Clinical Practice, EarlyView.
ABSTRACT Hidradenitis suppurativa (HS) is a chronic inflammatory skin disorder affecting intertriginous areas. Long‐standing HS can undergo malignant transformation into squamous cell carcinoma (SCC), particularly in the perineal and gluteal regions. We report a 54‐year‐old man with severe, treatment‐refractory HS complicated by an aggressive verrucous
Michael Zolotas, Tereza Jakovljevicova, Kamran Ghoreschi, Kerstin Kusch, Marisa Klemp, Robert Sabat, Georgios Kokolakis   +6 more
wiley   +1 more source

Cutaneous Rosai‐Dorfman Disease With MAP2K1 Mutation Treated With Encorafenib and Binimetinib

JEADV Clinical Practice, EarlyView.
ABSTRACT Rosai‐Dorfman disease (RDD) is a rare histiocytic disorder with unifocal to multisystemic involvement. Activating mutations in the MAPK/ERK pathway can occur in up to 50% of RDD cases. We report a case of cutaneous RDD (C‐RDD) with facial and truncal lesions harboring an activating MAP2K1 (MEK1) mutation that showed a complete response to a ...
Melike Ak, Reinhard Dummer, Egle Ramelyte   +2 more
wiley   +1 more source

Colitis as the Sole Initial Presentation of Chronic Granulomatous Disease: Histopathologic Clues to Diagnosis.

, 2016
Chronic granulomatous disease is a rare, inherited immunodeficiency disorder that reduces the superoxide generation ability of phagocytes, leading to recurrent infections and granulomatous inflammation.
Vuppula, Sharon, Rosenbaum, Brooke E, Thomas, Kristen, Shenoy, Rivfka, Moy, Libia, Kaul, Aditya   +5 more
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Surgical Reconstruction of Ulcers in Chronic Granulomatous Disease

Plastic and Reconstructive Surgery, Global Open
Summary:. Chronic granulomatous disease can affect multiple organ systems and is associated with poor wound healing, which may preclude a patient from undergoing a bone marrow transplant.
Lucas A. Dvoracek, MD, Winston R. Owens, BS, Vamsi C. Mohan, MD, Amjed Mohammad Saeed Abu-Ghname, MD, Howard Pryor, MD   +4 more
doaj   +1 more source

Eczema‐Like Amelanotic Melanoma: A Diagnostic Challenge

JEADV Clinical Practice, EarlyView.
ABSTRACT Amelanotic melanoma (AM) is a rare and aggressive variant of cutaneous melanoma characterised by the absence of pigmentation, often leading to delayed diagnosis due to its ability to mimic benign inflammatory or neoplastic conditions. We report the case of a 68‐year‐old woman presenting with a slowly enlarging, erythematous, mildly scaling ...
Agata Janowska, Valerio Ortenzi, Andrea della Maggiora, Nicolò Mori, Cristian Fidanzi, Marco Romanelli, Valentina Dini, Antonio Giuseppe Naccarato, Cristian Scatena   +8 more
wiley   +1 more source

Schistosoma mansoni in mice: modulation of granulomatous response after reinfection and chemotherapeutic treatment

Revista da Sociedade Brasileira de Medicina Tropical, 1994
Mice previously infected with Schistosoma mansoni, and cured by specific treatment (400mg/kg oxamniquine, p. o.) in the chronic phase of the disease, were reinfected 20 days after treatment to assess their capacityfor modulation ofthe granulomatous ...
Paulo Marcos Z. Coelho, Pedro Raso, Rômulo Teixeira de Mello, Nivaldo H. Toppa   +3 more
doaj   +1 more source

Chronic granulomatous disease; Three different clinical presentation [PDF]

, 2017
Chronic granulomatous disease is an inherited disorder of nicotinamide-adenine dinucleotide phosphate oxidase and results in a defect in intracellular killing of ingested microorganisms characterized by recurrent life threatening bacterial and fungal ...
Ceyhan, Meltem, Sensoy, Gulnar, Koker, Mustafa Yavuz, Yildiran, Alisan, Belet, Nursen, Celiksoy, Mehmet Halil   +5 more
core   +1 more source

Pericardial effusions in two boys with chronic granulomatous disease. [PDF]

, 1999
Pediatr Radiol. 1999 Nov;29(11):820-2. Pericardial effusions in two boys with chronic granulomatous disease. Macedo F, McHugh K, Goldblatt D. SourceDepartment of Radiology, Hospital Geral de Santo Antonio, Porto, Portugal.
MCHUGH, K., MACEDO, F., GOLDBLATT, D.
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