ABSTRACT Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare and potentially life‐threatening systemic, inflammatory disease with multi‐organ manifestations, variable presentation and complex pathology. Multiple interconnected immunological pathways are implicated in EGPA pathology, including a type‐2 immune response driving predominantly ...
Harold Wilson‐Morkeh +7 more
wiley +1 more source
Cardiac Granulomatous Disease Following Silicone Breast Augmentation: A Rare Cause of Symptomatic Sinus Node Dysfunction. [PDF]
Davidson N +5 more
europepmc +1 more source
Granuloma annulare: not as simple as it seems. [PDF]
Parish, Lawrence Charles +1 more
core +1 more source
The “White line sign”: A novel sonographic soft marker of pelvic endometriosis
The “White line sign” represents thickening of the subperitoneal tissue overlying the anterior pouch of Douglas on transvaginal ultrasound. It demonstrated high specificity for detecting superficial endometriosis and high specificity, sensitivity, and accuracy for deep endometriosis. It was also reproducible and could be a useful soft ultrasound marker
Prubpreet Chaggar +4 more
wiley +1 more source
Interferon-gamma 1b-induced gene expression alters neutrophil function in patients with chronic granulomatous disease. [PDF]
Ambruso DR +8 more
europepmc +1 more source
The Paediatric BCG Vaccine Century: From Historical Success to Future Innovations
ABSTRACT Aim The tuberculosis (TB) vaccine, Bacille‐Calmette‐Guérin (BCG), protects infants against severe forms of primary TB. Yet, it does not protect against pulmonary reactivation TB in adults. Methods A literature review was conducted between 1st January and 28th February 2025 using PubMed, Google Scholar and reports of the World Health ...
Stefan H. E. Kaufmann
wiley +1 more source
Targeted gene editing and near-universal cDNA insertion of CYBA and CYBB as a treatment for chronic granulomatous disease. [PDF]
Wolff JH +14 more
europepmc +1 more source
Bleeding Disorders in Children With Genetic Diseases: A Narrative Review
ABSTRACT Aim The lack of data on bleeding risk assessment in children with genetic diseases is concerning given their increased care needs and risk of haemorrhagic complications compared to the general population. Identification of haemostatic disorders is crucial for implementing preventive measures and mitigating bleeding risk.
Raphaelle Cagol +6 more
wiley +1 more source
Mold infections in chronic granulomatous disease patients-what comes to the rescue? [PDF]
von Bernuth H, Güngör T.
europepmc +1 more source
Mycosis fungoides and Sézary syndrome
Summary Mycosis fungoides (MF) and Sézary syndrome (SS) are the most common cutaneous T‐cell lymphomas, arising from mature CD4+ memory T cells. Diagnosis is complex and relies on clinicopathological correlation, immunophenotyping and molecular clonality testing, while management is stage‐adapted, with potentially curative outcomes achievable only in ...
Francisco Martins, Joana Calvão
wiley +1 more source

