Results 271 to 280 of about 124,984 (329)

High-fidelity PAMless base editing of hematopoietic stem cells to treat chronic granulomatous disease. [PDF]

Sci Transl Med
Bzhilyanskaya V, Ma L, Liu S, Fox LR, Whittaker MN, Meis RJ, Choi U, Lawson A, Ma M, Theobald N, Burkett S, Sweeney CL, Lazzarotto CR, Tsai SQ, Lack JB, Wu X, Dahl GA, Malech HL, Kleinstiver BP, De Ravin SS.   +19 more
europepmc   +1 more source

Equine epiglottitis: Diagnosis, treatment and outcome

Equine Veterinary Journal, EarlyView.
Abstract Background Epiglottitis is an uncommon upper airway pathology manifested endoscopically by mucosal oedema, reddening and thickening of the epiglottic mucosa. Literature on epiglottitis in horses is sparse. Objectives To describe the diagnosis, treatment and outcome of Thoroughbred and Standardbred racehorses diagnosed with epiglottitis at a ...
Carlos Jimenez, Patricia Hogan, Reza Belaghi, Alexandra Curtiss   +3 more
wiley   +1 more source

The potential value of cytokine, cortisol and vitamin D profiles in foals from birth to weaning for respiratory disease prediction on a farm endemic for Rhodococcus equi pneumonia

Equine Veterinary Journal, EarlyView.
Abstract Background Rhodococcus equi causes pneumonia in young foals, but disease susceptibility and severity vary. Cortisol and vitamin D modulate immune responses and cytokine production during bacterial infection, and altered concentrations are associated with sepsis in neonatal foals. We hypothesised an age and disease effect on circulating steroid
Londa J. Berghaus, Monica Venner, Hannah Helbig, Dorothea Hildebrandt, Kelsey Hart   +4 more
wiley   +1 more source

A rare case of lepromatous leprosy in Germany

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Roman Saternus, Gisela Bretzel, Tamaz Tsulaia, Kristin Burckhardt, Krista Yordanova, Sophie Elisabeth Müller, Steffen Jahn, Thomas Vogt, Sophie Schneitler   +8 more
wiley   +1 more source

Lung organoids as a human system for Mycobacteria infection modeling and drug testing

The FEBS Journal, EarlyView.
Mycobacterial infections, including tuberculosis (TB) and infections by nontuberculous mycobacteria (NTM), are still public health issues. In 2023, TB caused 1.25 million deaths, while NTM remain a clinical challenge for patients with cystic fibrosis (CF).
Stephen Adonai Leon‐Icaza, Romain Vergé, Raoul Mazars, Laurence Berry, Céline Cougoule   +4 more
wiley   +1 more source

Single-cell and spatial transcriptomics reveal the pathogenesis of chronic granulomatous disease in a natural model

Yu H, Zhang G, Ma Y, Ding J, Liu J, Zhou Z, Jiao S, Dong G, Cai Z.   +8 more
europepmc   +1 more source

Acneiform type of mogamulizumab‐associated rash

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Inga Hansen‐Abeck, Glenn Geidel, Finn Abeck, Anne Menz, Stefan W. Schneider, Nina Booken   +5 more
wiley   +1 more source

Dendritic Cell‐Depleted Mice Develop the Autoimmune Biliary Disease That Serologically and Pathogenically Models Human Primary Biliary Cholangitis

Hepatology Research, EarlyView.
ABSTRACT Aim Primary biliary cholangitis (PBC) is an autoimmune liver disease marked by progressive bile duct damage, leading to bile retention. Dendritic cells (DCs), as antigen‐presenting cells, are crucial for immune regulation, and their dysfunction is linked to autoimmunity.
Jiaqi Zhang, Ryo Nakagawa, Qingpeng Xu, Ke Hu, Lin Ru, Hayato Nakagawa, Yoshihiro Hirata   +6 more
wiley   +1 more source

Discoid lupus erythematosus associated with chronic granulomatous disease. [PDF]

Dermatol Reports
de Almeida Figueiredo AC, Matos AL, Calvão J, Cardoso JC.   +3 more
europepmc   +1 more source

Pathology reporting of hepatoblastoma resections: recommendations from the international collaboration on cancer reporting

Histopathology, EarlyView.
This is the first international dataset for the reporting of hepatoblastoma resection specimens produced by the International Collaboration on Cancer Reporting (ICCR). The aim is to standardize pathology reports, facilitating international data comparisons and improving management of hepatoblastoma on a global level.
Dolores H López‐Terrada, Fleur Webster, Rita Alaggio, Jonathan W Bush, Soo‐Jin Cho, Ronald R de Krijger, Takeshi Inoue, Allison F O'Neill, Antonio R Perez‐Atayde, Sarangarajan Ranganathan, Jens Stahlschmidt, Yukichi Tanaka, Marta Cohen, Miguel Reyes‐Múgica   +13 more
wiley   +1 more source