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Dermatologic Clinics, 2020
Granulomatous diseases are chronic inflammatory disorders whose pathogenesis is triggered by an array of infectious and noninfectious agents, and may be localized or a manifestation of systemic, disseminated disease. As in the skin, oral manifestations of granulomatous inflammation are often nonspecific in their clinical appearance.
Faizan Alawi +3 more
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Granulomatous diseases are chronic inflammatory disorders whose pathogenesis is triggered by an array of infectious and noninfectious agents, and may be localized or a manifestation of systemic, disseminated disease. As in the skin, oral manifestations of granulomatous inflammation are often nonspecific in their clinical appearance.
Faizan Alawi +3 more
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Internal and Emergency Medicine, 2011
Chronic granulomatous disease (CGD) is a rare primary immunodeficiency due to an abnormal function of the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase; NADPH oxidase is a key enzyme for the cellular "respiratory burst", the cellular process that converts molecular oxygen to the oxygen free-radical superoxide.
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Chronic granulomatous disease (CGD) is a rare primary immunodeficiency due to an abnormal function of the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase; NADPH oxidase is a key enzyme for the cellular "respiratory burst", the cellular process that converts molecular oxygen to the oxygen free-radical superoxide.
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Pediatric Clinics of North America, 1977
Since 1971, significant deviations from the classic pattern of chronic granulomatous disease have been recognized, and the disease appears to be more common that it did formerly. Knowledge of the basic underlying molecular defect has been broadened, and some new concepts of diagnosis and management have been formed. This report summarizes new knowledge
Richard B. Johnston, Simon L. Newman
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Since 1971, significant deviations from the classic pattern of chronic granulomatous disease have been recognized, and the disease appears to be more common that it did formerly. Knowledge of the basic underlying molecular defect has been broadened, and some new concepts of diagnosis and management have been formed. This report summarizes new knowledge
Richard B. Johnston, Simon L. Newman
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Current Gastroenterology Reports, 2009
Hepatic granulomas are often encountered on liver biopsy and may represent a primary hepatic process, a manifestation of a systemic illness, or an innocent finding of no clinical relevance. Hepatic granulomas are a unique inflammatory response that may be idiopathic or may be a response to a bacterial, fungal, viral, or parasitic infection; a ...
Sidharth S. Bhardwaj +2 more
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Hepatic granulomas are often encountered on liver biopsy and may represent a primary hepatic process, a manifestation of a systemic illness, or an innocent finding of no clinical relevance. Hepatic granulomas are a unique inflammatory response that may be idiopathic or may be a response to a bacterial, fungal, viral, or parasitic infection; a ...
Sidharth S. Bhardwaj +2 more
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Current Treatment Options in Gastroenterology, 2000
In the United States, the majority of patients with granulomatous liver disease do not have an identifiable cause. When a specific diagnosis can be made, therapy should be directed at eradicating the cause. A plan of management must recognize the drug history and nationality of the patient, chest radiograph, slit lamp examination of the eyes, skin ...
Hamid Hussain, Martin Black
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In the United States, the majority of patients with granulomatous liver disease do not have an identifiable cause. When a specific diagnosis can be made, therapy should be directed at eradicating the cause. A plan of management must recognize the drug history and nationality of the patient, chest radiograph, slit lamp examination of the eyes, skin ...
Hamid Hussain, Martin Black
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Granulomatous Disease of the Testis
Journal of Urology, 1980Granulomatous disease of the testis may have a specific cause or it may be idiopathic. We found 3 specific agents as the cause of the disease in a retrospective review of 17 cases of granulomatous disease of the testis. Mycobacterium tuberculosis was the most common cause of subsequent granulomatous orchitis.
Robert I. Kahn, Jack W. McAninch
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Granulomatous disease in the head and neck: developing a differential diagnosis.
Radiographics, 2014Granulomatous diseases have a varied etiology that includes autoimmune, infectious, idiopathic, and hereditary causes. The unifying factor in these diseases is the formation of granulomas, which histologically are mononuclear inflammatory cells or ...
O. Kenechi Nwawka +3 more
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The Immunogenetics of Granulomatous Diseases
2022Non-infectious granulomatous skin diseases are a wide category of well-defined reactive inflammatory conditions that share main similarities. While cutaneous sarcoidosis is the prototype of non-infectious (sterile) granulomatous dermatitides, there are several other entities in this group including granuloma annulare and necrobiosis lipoidica.
Gizem Filazi Kök, Ümit Türsen
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Annual Review of Medicine, 1992
Chronic granulomatous disease (CGD) encompasses a group of rare inherited disorders characterized by defects in a phagocyte-specific NADPH-oxidase complex that forms the superoxide radical during the respiratory burst. In this chapter, the protein components and cellular biochemistry of the oxidase are reviewed in light of recent genetic and ...
M C, Dinauer, S H, Orkin
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Chronic granulomatous disease (CGD) encompasses a group of rare inherited disorders characterized by defects in a phagocyte-specific NADPH-oxidase complex that forms the superoxide radical during the respiratory burst. In this chapter, the protein components and cellular biochemistry of the oxidase are reviewed in light of recent genetic and ...
M C, Dinauer, S H, Orkin
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