Results 31 to 40 of about 10,530,048 (339)

Topical tacrolimus 0.1% ointment for treatment of cutaneous Crohn's Disease [PDF]

, 2013
Peer reviewedPublisher ...
El-Omar, Emad, Keenan, Ronald A, Ormerod, Anthony D, Rice, Shantini A, Woo, Pick N   +4 more
core   +2 more sources

A homozygous loss-of-function mutation leading to CYBC1 deficiency causes chronic granulomatous disease

Nature Communications, 2018
Mutations in genes encoding subunits of the phagocyte NADPH oxidase complex are recognized to cause chronic granulomatous disease (CGD), a severe primary immunodeficiency.
G. Arnadottir, G. Norddahl, Steinunn Gudmundsdottir, A. Agustsdottir, S. Sigurdsson, B. Jensson, Kristbjorg Bjarnadottir, Fannar Theódórs, S. Benonisdottir, Erna V. Ivarsdottir, A. Oddsson, Ragnar P. Kristjansson, G. Sulem, Kristjan F. Alexandersson, Thorhildur Juliusdottir, Kjartan R. Gudmundsson, J. Saemundsdottir, Adalbjorg Jonasdottir, Á. Jónasdóttir, A. Sigurdsson, P. Manzanillo, S. A. Gudjonsson, Gudmundur A. Thorisson, O. Magnusson, G. Másson, K. Orvar, H. Hólm, Sigurdur Bjornsson, R. Arngrímsson, D. Gudbjartsson, U. Thorsteinsdóttir, I. Jónsdóttir, Á. Haraldsson, P. Sulem, K. Stefánsson   +34 more
semanticscholar   +1 more source

Differential Kinetics of Aspergillus nidulans and Aspergillus fumigatus Phagocytosis [PDF]

, 2017
Acknowledgements: The authors would like to acknowledge Fraser P. Coxon and Ian Ganley for providing LC3-GFP-mCherry BMDMs. M.S.G. was supported by an FEMS research grant and F.L.v.d.V.
Alonso, M Fernanda, Bain, Judith M, Becker, Katharina L, Erwig, Lars P, Gresnigt, Mark S, Leenders, Floris, Meis, Jacques F, van de Veerdonk, Frank L, Wang, Xiaowen   +8 more
core   +2 more sources

Idiopathic Granulomatous Mastitis: A Clinical Puzzle in Breast Lump Cases [PDF]

Journal of Clinical and Diagnostic Research, 2017
Idiopathic granulomatous mastitis (IGM) is a rare benign disease, characterized by chronic inflammation and granulomatous disease process. A middle aged lady with breast lump for six months with equivocal mammographic and ultrasound results underwent ...
Vivek G Nath, Rakesh Sahoo, Avinash Sahoo, Jithendra Kumar Barad, K A Arun   +4 more
doaj   +1 more source

Interferon regulatory factor 8-deficiency determines massive neutrophil recruitment but T cell defect in fast growing granulomas during tuberculosis [PDF]

, 2013
Following Mycobacterium tuberculosis (Mtb) infection, immune cell recruitment in lungs is pivotal in establishing protective immunity through granuloma formation and neogenesis of lymphoid structures (LS).
A Dorhoi, A Fortin, A Kahnert, A Mantovani, AM Becker, Anna Giagu, Antonio Giovanni Anfossi, CY Chen, DM Carragher, DM Lowe, E Corsiero, Elisabetta Antuofermo, F Mattei, Fabrizio Mattei, Filippo Belardelli, G Delogu, G Schiavoni, Giovanna Schiavoni, Giovanni Delogu, Giovanni Fadda, HP Gideon, Ivana Palucci, JF Marquis, JG Egen, JL Flynn, K Turcotte, K Turcotte, KB Urdahl, KK Huynh, L Gabriele, L Guglani, L Ramakrishnan, Laura Abalsamo, Lucia Gabriele, M Behr, M Munder, M Sali, Massimo Sanchez, MC Tsai, ME El Shikh, Michela Sali, MP Berry, NA Giese, Olivier Neyrolles, P Tailor, PJ Maglione, RL Hunter, S Hambleton, S Kunnath-Velayudhan, SA Luther, SS Kashino, Stefano Rocca, SY Foo, T Holtschke, T Ulrichs, TA Day, TD Randall, X Zhou, Y Yoshikai   +58 more
core   +3 more sources

Chronic Granulomatous Disease: Epidemiology, Pathophysiology, and Genetic Basis of Disease

Journal of the Pediatric Infectious Diseases Society, 2018
Chronic Granulomatous Disease is one of the classic primary immunodeficiencies of childhood. While the incidence and severity of bacterial and fungal infections have been greatly reduced in this patient population, much remains to be learned about the ...
N. Rider, M. Jameson, C. B. Creech
semanticscholar   +1 more source

Chronic Granulomatous Disease: the Experience of Diagnosis and Treatment in Children

Zdorovʹe Rebenka, 2013
Chronic granulomatous disease — primary immunodeficiency with X-linked and autosomal recessive inheritance, characterized by impaired bactericidal function of phagocytic immune system.
L.I. Chernyshova, A.P. Volokha, A.V. Bondarenko, A.M. Gilfanova, V.P. Chernyshov   +4 more
doaj   +1 more source

Hydrocephalus as the presenting symptom of sarcoidosis: A case report and review of literature

Clinical Case Reports, 2020
Hydrocephalus is rare in sarcoidosis, especially as the presenting symptom. Neurosarcoidosis as a cause of unexplained communicating hydrocephalus should be considered in cases of abnormal cerebrospinal fluid (CSF) and negative infectious and tumoral ...
Rachel J. Saban, Meaghan M. Berns, Mazen M. Al‐Hakim, Gustavo A. Patino   +3 more
doaj   +1 more source

Nasal manifestations in granulomatosis with polyangiitis: a case report and review of the literature [PDF]

, 2018
Granulomatosis with polyangiitis (GPA) is an anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides of medium and small arteries, characterized by necrotizing granulomatous inflammation of the upper and lower respiratory tract with coexist ...
D'AGUANNO, VITTORIO, DE VINCENTIIS, Marco, FALASCA, VINCENZO, GRECO, Antonio, RALLI, MASSIMO, TURCHETTA, Rosaria   +5 more
core   +1 more source

EROS mutations: decreased NADPH oxidase function and chronic granulomatous disease

Journal of Allergy and Clinical Immunology, 2018
Capsule Summary We demonstrate for the first time that EROS (CYBC1/C17ORF62) regulates abundance of the gp91phox-p22phox heterodimer of the phagocyte NADPH oxidase in human cells and that EROS mutations are a novel cause of chronic granulomatous disease.
D. Thomas, L. Charbonnier, Andrea Schejtman, Hasan Aldhekri, Eve L. Coomber, Elizabeth R. Dufficy, Anne E. Beenken, James C. Lee, S. Clare, A. Speak, A. Thrasher, G. Santilli, H. Al-Mousa, F. Alkuraya, T. Chatila, Kenneth G. C. Smith   +15 more
semanticscholar   +1 more source