Results 41 to 50 of about 10,530,048 (339)

Noninfectious Manifestations and Complications of Chronic Granulomatous Disease

Journal of the Pediatric Infectious Diseases Society, 2018
Chronic granulomatous disease (CGD), a primary immunodeficiency characterized by a deficient neutrophil oxidative burst and the inadequate killing of microbes, is well known to cause a significantly increased risk of invasive infection.
S. Henrickson, A. Jongco, Kelly F. Thomsen, E. Garabedian, I. Thomsen   +4 more
semanticscholar   +1 more source

TL1A/DR3 axis involvement in the inflammatory cytokine network during pulmonary sarcoidosis [PDF]

, 2015
BACKGROUND: TNF-like ligand 1A (TL1A), a recently recognized member of the TNF superfamily, and its death domain receptor 3 (DR3), firstly identified for their relevant role in T lymphocyte homeostasis, are now well-known mediators of several immune ...
A. Cabrelle, A. Teramo, C Agostini, C Agostini, C Agostini, C Agostini, C Agostini, C Agostini, C. Agostini, F Meylan, F. Calabrese, F. Calzetti, F. Cinetto, G Bamias, G Bamias, G Bamias, G Mautino, G. Semenzato, GW Jones, J Müller-Quernheim, KA Oswald-Richter, KL Wallace, KS Lee, L Li, L Nissinen, M Facco, M Facco, M. A. Cassatella, M. Facco, MA Cassatella, MA Judson, MT Henry, N Kamada, N Kamada, N. Tamassia, R Polverosi, RE Vandenbroucke, S. Carraro, SK Bedoya, TH Schreiber, TS Migone, V. Martini, VY Taraban, X Sun, Y Aiba, YJ Kang   +45 more
core   +1 more source

Treatment of idiopathic granulomatous mastitis and factors related with disease recurrence

Turkish Journal of Medical Sciences, 2020
Background/aim Idiopathic granulomatous mastitis is a rare, benign inflammatory disease of breast. There is no general agreement on the appropriate treatment choice.
Emre Tekgöz, S. Çolak, M. Çınar, S. Yılmaz   +3 more
semanticscholar   +1 more source

Disseminated perforating necrobiosis lipoidica: A case report and literature review

Clinical Case Reports, 2023
Key Clinical Message Necrobiosis lipoidica is a rare cutaneous granulomatous disease that mainly affects diabetic patients. The perforating type of the disease is an uncommon variant that is resistant to therapy and can be easily identified using ...
Mina Saber, Fatemeh Mohaghegh, Parisa Mohammadian   +2 more
doaj   +1 more source

Persistent Inflammation and Nitric Oxide Dysregulation Are Transcriptomic Blueprints of Subglottic Stenosis

Frontiers in Immunology, 2021
Subglottic stenosis (SGS) is a recurrent, obstructive, fibroinflammatory disease of the upper airway resulting in severe dyspnea, dysphonia, as well as other potentially fatal complications.
Hoang C. B. Nguyen, Tiffany N. Chao, Tiffany N. Chao, Noam A. Cohen, Noam A. Cohen, Natasha Mirza, Natasha Mirza   +6 more
doaj   +1 more source

Considerations in the Diagnosis of Chronic Granulomatous Disease

Journal of the Pediatric Infectious Diseases Society, 2018
Chronic granulomatous disease (CGD) is a rare primary immunodeficiency that is caused by defects in the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase complex. The disease presents in most patients initially with infection, especially of the
Joyce E. Yu, A. Azar, H. Chong, A. Jongco, B. Prince   +4 more
semanticscholar   +1 more source

Genetic predisposition to porto‐sinusoidal vascular disorder: A functional genomic‐based, multigenerational family study

Hepatology, EarlyView., 2022
A deleterious variant of FCHSD1 results in mTOR pathway overactivation and may cause porto‐sinusoidal vascular disorder (PSVD). The pedigree of the family demonstrated an autosomal dominant disease with variable expressivity. Whole‐genome sequencing and Sanger sequencing both validated the existence of the FCHSD1 variant and the heterozygosity of c ...
Jingxuan Shan, André Megarbane, Aziz Chouchane, Deepak Karthik, Ramzi Temanni, Atilio Reyes Romero, Huiying Hua, Chun Pan, Xixi Chen, Murugan Subramanian, Chadi Saad, Hamdi Mbarek, Cybel Mehawej, Eliane Chouery, Sirin W. Abuaqel, Alexander Dömling, Sami Remadi, Cesar Yaghi, Pu Li, Lotfi Chouchane   +19 more
wiley   +1 more source

Chronic Granulomatous Disease

Hematology/Oncology Clinics of North America, 2009
Chronic granulomatous disease (CGD) was first described in the 1950s and has become a paradigm for genetic neutrophil diseases. It is characterized by recurrent infections with a narrow spectrum of bacteria and fungi as well as a common set of inflammatory complications most notably including inflammatory bowel disease. Over the last half century major
B H, Segal, L, Romani, P, Puccetti
openaire   +5 more sources

First Case of Systemic Coronavirus Infection in a Domestic Ferret (Mustela putorius furo) in Peru. [PDF]

, 2015
A domestic ferret from Lima, Peru, died after ten days of non-specific clinical signs. Based on pathology, immunohistochemistry and molecular analysis, ferret systemic coronavirus (FRSCV)-associated disease was diagnosed for the first time in South ...
Gonzales-Viera, O, Gregori, F, Keel, MK, Lescano, J, Luna, L, Quevedo, M   +5 more
core   +1 more source

Gastrointestinal Disorders Associated with Common Variable Immune Deficiency (CVID) and Chronic Granulomatous Disease (CGD)

Current Gastroenterology Reports, 2016
Common variable immune deficiency (CVID) and chronic granulomatous disease (CGD) are two of the well-characterized primary immune deficiencies with distinct pathologic defects. While CVID is predominantly a disorder of the adaptive immune system, in CGD,
M. Uzzan, H. Ko, S. Mehandru, C. Cunningham-Rundles   +3 more
semanticscholar   +1 more source