Results 71 to 80 of about 552,251 (241)

NEMO‐NDAS: Case Report and Review of the Literature

Pediatric Dermatology, EarlyView.
ABSTRACT NEMO‐deleted exon 5 autoinflammatory syndrome (NEMO‐NDAS) is the result of a gain‐of‐function IKBKG pathogenic variant leading to dysregulated NF‐κB signaling and systemic inflammation. We present a case of NEMO‐NDAS in a 2‐year‐old female presenting with recurrent fevers, subcutaneous nodules, lymphadenopathy, and splenomegaly.
Angela Yang, Kristie Mar, Kimberly A. Morishita, Kevin Meesters, Antonio Torrelo, Joseph M. Lam   +5 more
wiley   +1 more source

Roles of TLR7 in Schistosoma japonicum Infection-Induced Hepatic Pathological Changes in C57BL/6 Mice

Frontiers in Cellular and Infection Microbiology, 2021
S. japonicum infection can induce granulomatous inflammation in the liver of the host. Granulomatous inflammation limits the spread of infection and plays a role in host protection.
Yuanfa Feng, Yuanfa Feng, Hongyan Xie, Feihu Shi, Dianhui Chen, Dianhui Chen, Anqi Xie, Jiajie Li, Chao Fang, Haixia Wei, He Huang, Xingfei Pan, Xiaoping Tang, Jun Huang   +13 more
doaj   +1 more source

NOD2 and inflammation: current insights [PDF]

, 2018
The nucleotide-binding oligomerization domain (NOD) protein, NOD2, belonging to the intracellular NOD-like receptor family, detects conserved motifs in bacterial peptidoglycan and promotes their clearance through activation of a proinflammatory ...
Cucchiara, Salvatore, Negroni, Anna, Pierdomenico, Maria, Stronati, Laura   +3 more
core   +2 more sources

Comparison of Rifampin and Isoniazid for Latent Tuberculosis Infection in Kidney Transplant Candidates: Focus on Tolerability and Treatment Completion

Transplant Infectious Disease, EarlyView.
This study comparing 4‐month rifampin with 9‐month isoniazid for latent tuberculosis in kidney transplant candidates showed higher treatment completion rates and no transaminase elevations in the rifampin group. However, some patients experienced an increase in blood pressure while taking antihypertensive medications known to interact with rifampin ...
Jacques Simkins, Julia Bini Viotti, Yoichiro Natori, Shweta Anjan, Adela Mattiazzi, Mariella Ortigosa‐Goggins, Giselle Guerra, David Roth, Warren Kupin, Javier A. Pagan, Franco Cabeza, Gaetano Ciancio, Mahmoud Morsi, Michele I. Morris   +13 more
wiley   +1 more source

Development and validation of BCG vaccine‐induced novel granulomatous liver injury preclinical animal model

Animal Models and Experimental Medicine
Background Developing a granulomatous liver injury preclinical model may pave the way to understanding hepatic‐TB (tuberculosis) and autoimmune granulomatous liver diseases.
Swati Sharma, Abhishek Moudgil, Jyoti Grewal, Pankaj Khatri, Vishal Sharma, Madhumita Premkumar, Amanjit Bal, Dibyajyoti Banerjee, Amol N. Patil   +8 more
doaj   +1 more source

Localized hepatic tuberculosis presenting as fever of unknown origin

Brazilian Journal of Infectious Diseases
Localized hepatic tuberculosis is a rare clinical form of tuberculosis infection; it has signs and symptoms related only to hepatic injury, with minimal or no extrahepatic involvement.
Teresa Cristina Abreu Ferrari, Carolina Mundim Couto, Tatiane Silva Vilaça, Marcelo Antônio Pascoal Xavier   +3 more
doaj   +1 more source

Application and Challenges of Chimeric Antigen Receptor T Cell Therapy in Systemic Rheumatic Diseases and Autoimmune Disorders

MedComm, Volume 7, Issue 4, April 2026.
CAR‐T cell therapy in systemic rheumatic diseases and autoimmune disorders. (This figure was created using BioRender.com.) ABSTRACT Chimeric antigen receptor T (CAR‐T) cell therapy, originally developed for hematologic malignancies, has emerged as a transformative candidate for systemic rheumatic diseases and autoimmune disorders (AIDs).
Zhidan Fan, Li Zhang, Haiguo Yu
wiley   +1 more source

Chronic Hepatitis with Liver Granulomas in a Patient with Granuloma Annulare: A Case Report and Review of the Literature

Case Reports in Gastrointestinal Medicine, 2017
Granuloma annulare (GA) is a benign granulomatous skin disorder of unknown etiology. GA is rarely associated with liver diseases. We report a unique case of chronic hepatitis with liver granulomas in a patient with GA.
Majid Alsahafi, Mohammed I. AlJasser, Sunil Kalia, H. M. Yang, Alnoor Ramji   +4 more
doaj   +1 more source

Is it Crohn's disease? A severe systemic granulomatous reaction to sulfasalazine in patient with rheumatoid arthritis

BMC Gastroenterology, 2001
Background Sulfasalazine is a widely used anti-inflammatory agent in the treatment of inflammatory bowel disease and several rheumatological disorders.
Haftel Hilary M, Greenson Joel, Quallich Leonard G, Fontana Robert J   +3 more
doaj   +1 more source

[Bacterial granulomatous hepatitis].

Le infezioni in medicina, 2003
The liver may react to different infectious and non- infectious agents, developing granulomatous lesions which characterize granulomatous hepatitis. Granulomas of the liver are circumscribed inflammatory lesions (size from 50 to 300 mm) composed of epithelioid cells, varied numbers of mononuclear cells and eosinophils and multinucleated giant cells ...
PASQUALE, Giuseppe, Scarano F, SAGNELLI, Caterina   +2 more
openaire   +2 more sources