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We present three-dimensional computed tomographic findings of a juvenile granulosa cell tumor of the ovary at FIGO stage IA in a 17-year-old woman. Juvenile granulosa cell tumor is one of the rare sex cord stromal tumors of the ovary. Most tumors at FIGO stage IA have a favorable prognosis, whereas those at higher stages have a less favorable outcome.
Fink D, Kubik-Huch RA, Wildermuth S
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ULTRASTRUCTURE OF A GRANULOSA CELL TUMOUR
Obstetrical & Gynecological Survey, 1970Abstract. The fine structure of a hormonal active granulosa cell tumour is described. The greater part of the tumour consisted of a cell type resembling the granulosa cell of the normal follicle. It contained many Golgi elements but was poor in smooth and rough endoplasmic reticulum.
P H, Pedersen, J F, Larsen
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Granulosa cell tumor in a goat
Journal of the American Veterinary Medical Association, 1986Granulosa cell tumors are rare in the goat. This report deals with the shortened estrous cycles, masculinization, depressed fertility, and the systemic hormone profiles resulting from a granulosa cell tumor in a doe. Data are supported by unique information on the steroid content of the tumor.
R M, Lofstedt, R, Williams
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Pediatric Pathology, 1990
A 2-year-old girl presented with isosexual precocity, and a juvenile granulosa cell tumor of the left ovary was removed. The tumor was unusual in that striated muscle differentiation of the tumor cells was demonstrated. This suggests that the mesenchymal cells retain the potential for divergent differentiation.
F, Raafat, H, Klys, G, Rylance
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A 2-year-old girl presented with isosexual precocity, and a juvenile granulosa cell tumor of the left ovary was removed. The tumor was unusual in that striated muscle differentiation of the tumor cells was demonstrated. This suggests that the mesenchymal cells retain the potential for divergent differentiation.
F, Raafat, H, Klys, G, Rylance
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Bioencapsulation of Oocytes and Granulosa Cells
2023A protocol for the encapsulation in sodium alginate of granulosa cells in primary culture and coculture of oocyte-cumulus complexes is reported. Sodium alginate forms strong gels when jellified with barium ions, allowing the self-organization of cells into a 3D structure.
Faustini, Massimo +4 more
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Molecular and Cellular Endocrinology, 2004
The ovary is a complex endocrine gland responsible for production of sex steroids and is the source of fertilizable ova for reproduction. It also produces various growth factors, transcription factors and cytokines that assist in the complex signaling pathways of folliculogenesis. The ovary possesses two primary steroidogenic cell types.
Jon C, Havelock +2 more
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The ovary is a complex endocrine gland responsible for production of sex steroids and is the source of fertilizable ova for reproduction. It also produces various growth factors, transcription factors and cytokines that assist in the complex signaling pathways of folliculogenesis. The ovary possesses two primary steroidogenic cell types.
Jon C, Havelock +2 more
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Granulosa cell-oocyte interactions
European Journal of Obstetrics & Gynecology and Reproductive Biology, 2004Throughout oogenesis the oocyte and follicle cells establish an intricate system of mutual interactions that ultimately lead to the acquisition of their respective competences. Paracrine factors released by both cell types are believed to stimulate formation of the primordial follicle and support the initial phases of follicle growth. At the same time,
CECCONI, Sandra +4 more
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2018
Culture of granulosa cells has for long provided a useful tool to understand the molecular processes underlying ovarian follicle development. Among all species investigated, cattle have become an excellent model for in vitro studies on follicular biology, both because of their resemblance with humans in terms of follicular biology and the importance of
Bushra T, Mohammed, F Xavier, Donadeu
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Culture of granulosa cells has for long provided a useful tool to understand the molecular processes underlying ovarian follicle development. Among all species investigated, cattle have become an excellent model for in vitro studies on follicular biology, both because of their resemblance with humans in terms of follicular biology and the importance of
Bushra T, Mohammed, F Xavier, Donadeu
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Extraovarian Granulosa Cell Tumor
Gynecologic Oncology, 1999The aim of this study was to report a case of extraovarian granulosa cell tumor and to describe its relevance to the histologic origin of granulosa cell tumors and to clinical practice.The clinical course and histopathology of the case were reviewed, and a literature search for other reported cases was performed.A 67-year-old woman presented with ...
J B, Robinson +4 more
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Ultrastructure of a granulosa cell tumor
American Journal of Obstetrics and Gynecology, 1968Abstract Ultrastructural investigation of an ovarian granulosa cell tumor has revealed structural traits conforming to those of the normal, nonluteinized granulosa cell. Cytoplasmic membranous systems and mitochondria were well developed. Lipid inclusions were numerous. Nuclei demonstrated some degree of pleomorphism, and nucleoli were prominent. The
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