Results 101 to 110 of about 28,946 (223)
Abstract Objective Early detection of ovarian cancer at stage I is important to improve patients‘ prognosis. The goal of this study was to examine if transvaginal ultrasound (TVU) performed at the same time as cervical cancer screening can facilitate early detection of ovarian cancer.
Hiromasa Fujita +5 more
wiley +1 more source
Juvenile granulosa cell tumor of the testis: prenatal diagnosis and prescrotal approach
Neonatal testicular tumors are rare and should be considered in the differential diagnosis of newborn scrotal masses. Juvenile granulosa cell tumor (JGCT) accounts for about 5% of all prepubertal testis tumors.
Bulotta Anna Lavinia +6 more
doaj +1 more source
The Homeobox Genes: Classification, Regulation, Biological Functions, and Diseases
Overview of the homeobox gene superfamily and its pathophysiological roles. The homeobox superfamily comprises several major classes, including ANTP, PRD, TALE, LIM, POU, and others. Among these, the HOX clusters (A–D) play critical roles in embryonic development specifically in conferring cellular identity, regulating morphogenesis, and guiding axial ...
Maedeh Dadzadi +5 more
wiley +1 more source
Adult-type ovarian granulosa cell tumors are rare low-grade malignancies characterized by late recurrence and atypical clinical manifestations. This study reports two cases of recurrent adult-type ovarian granulosa cell tumor with distinct timelines and ...
Yutao Wang +3 more
doaj +1 more source
Microarray analysis of Foxl2 mediated gene regulation in the mouse ovary derived KK1 granulosa cell line: Over-expression of Foxl2 leads to activation of the gonadotropin releasing hormone receptor gene promoter [PDF]
Background The Foxl2 transcription factor is required for ovarian function during follicular development. The mechanism of Foxl2 regulation of this process has not been elucidated.
Jean M Escudero +3 more
core +1 more source
ABSTRACT Growth differentiation factor 9 (GDF9) plays a key role in enhancing developmental competence and blastocyst yield during in vitro maturation (IVM). This study investigated whether GDF9 could counteract the harmful effects of lipopolysaccharide (LPS), a gram‐negative bacterial component, on bovine in vitro embryo production, while also ...
Dragos Scarlet +4 more
wiley +1 more source
Understanding the dynamics of Toll-like Receptor 5 response to flagellin and its regulation by estradiol [PDF]
© 2017 The Author(s). Toll-like receptors (TLRs) are major players of the innate immune system. Once activated, they trigger a signalling cascade that leads to NF-ΰ B translocation from the cytoplasm to the nucleus. Single cell analysis shows that NF-ΰ
B Calippe +42 more
core +5 more sources
FB23‐2 potentiates cisplatin's antitumor efficacy in head and neck squamous cell carcinoma by disrupting XPF/ERCC1 complex assembly and nuclear translocation, thereby suppressing DNA damage repair machinery and amplifying platinum‐induced tumor cell death.
Yaoqi Jiang +7 more
wiley +1 more source
Ovarian steroid cell tumor with biallelic adenomatous polyposis coli inactivation in a patient with familial adenomatous polyposis [PDF]
Familial adenomatous polyposis (FAP) is an autosomal dominant cancer predisposition syndrome that accounts for approximately 0.5–1% of all colorectal cancer cases.
Abraham +36 more
core +1 more source
Abstract Menopause is the time when a woman transitions from the reproductive stage of life to the non‐reproductive state. It is characterised by significant hormonal changes, which can affect a woman's physical, emotional, mental and social well‐being.
Irene Bretón Lesmes +7 more
wiley +1 more source

